Gene Information

Name : yscN (CPn0707)
Accession : NP_224903.1
Strain : Chlamydophila pneumoniae CWL029
Genome accession: NC_000922
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 793701 - 795029 bp
Length : 1329 bp
Strand : -
Note : -

DNA sequence :
ATGGATCAGTTAACAACGGATTTCGACACTCTCATGTCACAACTTGGTGATGTGAATCTTACGACTGTAGTAGGCCGCAT
TACAGAAGTGGTCGGCATGTTAATCAAAGCCGTAGTTCCTAATGTGCGTGTTGGAGAAGTATGCTTAGTGAAACGTAACG
GCATGGAACCTCTCGTAACAGAAGTCGTTGGTTTTACCCAGAGTTTTGCCTTTCTCTCTCCTTTAGGAGAGTTATCAGGA
GTGAGTCCTTCTTCCGAAGTCATCCCTACAGGACTCCCCTTACACATTCGAGCAGGAAACGGCCTCTTAGGTCGTGTTCT
CAATGGGTTGGGAGAACCCATAGATGTAGAAACTAAAGGTCCATTACAAAATGTGGATCAAACATTTCCTATTTTTCGTG
CACCCCCAGATCCCCTGCATAGGGCGAAATTACGACAGATCCTGTCTACGGGTGTGCGTTGTATAGACGGTATGCTCACG
GTCGCTAGGGGGCAGCGTATTGGAATTTTTGCTGGTGCTGGAGTGGGAAAATCTTCGCTCTTAGGTATGATCGCAAGAAA
CGCTGAAGAAGCCGACGTTAATGTAATCGCGCTTATTGGAGAAAGGGGGCGTGAAGTACGTGAGTTTATAGAGGGGGATT
TGGGAGAAGAAGGAATGAAACGTTCCGTAATTGTCGTTTCTACTTCTGACCAATCGTCGCAATTGCGACTTAATGCCGCC
TATGTAGGGACTGCAATTGCAGAGTATTTTCGTGATCAAGGGAAAACTGTCGTACTTATGATGGATTCCGTGACACGATT
TGCTCGTGCATTGCGGGAAGTGGGGTTAGCCGCTGGAGAGCCTCCTGCTAGAGCAGGATACACTCCATCGGTTTTTTCCA
CTCTACCCCGTCTATTGGAAAGATCAGGAGCCTCCGATAAAGGAACCATTACAGCATTTTATACCGTCTTGGTAGCAGGA
GATGATATGAACGAGCCTGTTGCTGACGAAGTCAAATCGATTCTTGACGGGCATATTGTTCTCTCCAATGCACTAGCTCA
AGCATACCATTATCCTGCAATTGACGTACTTGCTTCGATTAGCCGACTCCTGACTGCTATTGTTCCTGAAGAACAACGAC
GGATCATAGGGAAAGCAAGAGAAGTTTTAGCTAAATATAAAGCCAACGAGATGTTGATCCGTATTGGAGAATACCGACGA
GGTTCTGATCGTGAGATAGATTTTGCTATCGACCATATTGACAAATTGAACCGGTTTTTAAAGCAAGATATCCACGAAAA
GACAAACTATGAGGAAGCAGCACAACAACTGCGCGCCATTTTCCGGTAA

Protein sequence :
MDQLTTDFDTLMSQLGDVNLTTVVGRITEVVGMLIKAVVPNVRVGEVCLVKRNGMEPLVTEVVGFTQSFAFLSPLGELSG
VSPSSEVIPTGLPLHIRAGNGLLGRVLNGLGEPIDVETKGPLQNVDQTFPIFRAPPDPLHRAKLRQILSTGVRCIDGMLT
VARGQRIGIFAGAGVGKSSLLGMIARNAEEADVNVIALIGERGREVREFIEGDLGEEGMKRSVIVVSTSDQSSQLRLNAA
YVGTAIAEYFRDQGKTVVLMMDSVTRFARALREVGLAAGEPPARAGYTPSVFSTLPRLLERSGASDKGTITAFYTVLVAG
DDMNEPVADEVKSILDGHIVLSNALAQAYHYPAIDVLASISRLLTAIVPEEQRRIIGKAREVLAKYKANEMLIRIGEYRR
GSDREIDFAIDHIDKLNRFLKQDIHEKTNYEEAAQQLRAIFR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 9e-105 56
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-94 53
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-94 53
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-95 53
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 3e-94 53
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-95 53
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-95 53
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 9e-96 53
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-94 53
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-94 53
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-81 52
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 5e-79 49
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-79 49
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-79 49
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-79 49
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-79 49
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-78 48
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-78 48
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 1e-75 47
escN AAC38383.1 EscN Virulence LEE Protein 4e-81 47
escN YP_003236088.1 translocator EscN Virulence LEE Protein 4e-81 47
escN AAK26715.1 EscN Virulence LEE Protein 4e-81 47
escN YP_003223475.1 translocator EscN Virulence LEE Protein 3e-81 47
escN AAL57542.1 EscN Virulence LEE Protein 4e-81 47
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-81 47
escN AAC31513.1 L0034 Virulence LEE Protein 3e-81 47
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 3e-81 47
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-78 47
escN CAI43874.1 EscN protein Virulence LEE Protein 2e-81 47
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-81 47
escN NP_290268.1 hypothetical protein Virulence LEE Protein 4e-81 47
ECs4568 NP_312595.1 EscN Virulence LEE Protein 4e-81 47
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 9e-78 46
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-78 46
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-78 46
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 4e-84 46
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 1e-82 46
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 4e-72 45
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 3e-68 45
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 3e-78 45
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-78 45
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 3e-78 45
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 3e-72 45
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 3e-72 45
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-68 44
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-64 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 3e-64 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-64 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-64 43
invC AAS66861.1 InvC Not tested SSR-2 Protein 1e-67 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yscN NP_224903.1 type III secretion system ATPase VFG2144 Protein 0.0 93
yscN NP_224903.1 type III secretion system ATPase VFG0192 Protein 7e-109 57
yscN NP_224903.1 type III secretion system ATPase VFG0048 Protein 4e-105 55
yscN NP_224903.1 type III secretion system ATPase VFG0390 Protein 1e-103 55
yscN NP_224903.1 type III secretion system ATPase VFG0515 Protein 1e-79 49
yscN NP_224903.1 type III secretion system ATPase VFG0812 Protein 2e-81 47
yscN NP_224903.1 type III secretion system ATPase VFG0730 Protein 3e-81 47
yscN NP_224903.1 type III secretion system ATPase VFG2459 Protein 4e-69 45
yscN NP_224903.1 type III secretion system ATPase VFG2331 Protein 8e-77 44
yscN NP_224903.1 type III secretion system ATPase VFG1254 Protein 1e-80 44
yscN NP_224903.1 type III secretion system ATPase VFG1778 Protein 2e-70 44
yscN NP_224903.1 type III secretion system ATPase VFG2499 Protein 2e-77 44
yscN NP_224903.1 type III secretion system ATPase VFG0555 Protein 1e-64 43
yscN NP_224903.1 type III secretion system ATPase VFG1008 Protein 2e-62 42