Gene Information

Name : clpB (CPn0144)
Accession : NP_224352.1
Strain : Chlamydophila pneumoniae CWL029
Genome accession: NC_000922
Putative virulence/resistance : Virulence
Product : Clp protease ATPase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 177963 - 180563 bp
Length : 2601 bp
Strand : +
Note : -

DNA sequence :
ATGGAGAAATTTTCCGATGCTGTCTCTGAAGCTTTAGAGAAGGCTTTCGAACTTGCTAAATCTTCGAAACATACCTATGT
CACAGAAAATCACCTATTACTGGCTTTATTAGAAAATACAGAGTCTCTCTTTTATTTGGTAATTAAGGACATTCATGGGA
ACCCTGGTTTGCTCAATACGGCAGTTAAAGATGCGCTCTCACGAGAGCCGACTGTAGTTGAAGGAGAGGTGGATCCTAAA
CCTTCTCCGGGTTTACAAACCCTTCTTAGGGATGCCAAACAAGAGGCAAAGACATTAGGAGATGAATACATTTCTGGAGA
TCATCTGCTGCTTGCTTTTTGGAGTTCAAACAAAGAGCCTTTTAATTCTTGGAAGCAAACAACAAAAGTTAGTTTTAAAG
ATCTTAAGAATCTGATTACTAAAATACGACGAGGAAATCGTATGGATTCGCCAAGCGCTGAAAGTAATTTTCAGGGTTTA
GAAAAGTATTGTAAAAATTTAACAGCATTAGCTCGTGAAGGTAAACTGGATCCTGTGATCGGTAGAGATGAAGAAATTCG
TAGAACCATCCAAGTGCTTTCCCGTAGAACTAAAAATAACCCTATGCTTATTGGTGAGCCGGGTGTAGGGAAAACTGCTA
TAGCAGAAGGATTAGCTCTTAGGCTTATCCAGGGTGATGTTCCTGAATCTCTCAAAGGTAAACAGCTTTATGTCTTAGAT
ATGGGAGCTTTGATTGCAGGAGCTAAGTATCGAGGTGAGTTTGAAGAAAGACTAAAGAGTGTTTTAAAAGATGTAGAATC
TGGAGATGGCGAGCACATTATCTTTATTGATGAGGTGCATACTCTTGTTGGAGCAGGAGCTACTGATGGAGCTATGGATG
CTGCGAATCTTTTAAAGCCTGCATTAGCAAGAGGGACGCTACACTGTATTGGCGCGACGACTTTGAATGAGTATCAGAAG
TATATTGAAAAAGATGCTGCTTTGGAACGTCGATTTCAGCCTATTTTTGTGACAGAGCCTTCTTTGGAGGATGCTGTCTT
TATTCTTCGTGGACTAAGAGAAAAATATGAAATTTTCCATGGAGTCAGGATTACAGAGGGGGCTTTGAATGCCGCAGTCC
TACTTTCCTATCGTTATATCCCAGATCGCTTTCTTCCAGATAAGGCTATCGATTTGATAGATGAAGCGGCAAGTTTAATT
CGCATGCAAATTGGTAGTCTTCCTCTTCCTATTGATGAAAAGGAGAGAGAGCTTGCTGCTTTGATCGTTAAGCAAGAGGC
TATAAAACGCGAGCAATCTCCTTCCTATCAAGAAGAGGCGGATGCTATGCAGAAGTCTATAGATGCTTTGAGAGAGGAAT
TAGCATCTCTACGTTTGGGTTGGGATGAAGAGAAGAAGTTGATTTCGGGGCTCAAGGAAAAAAAGAATTCCTTGGAAAGT
ATGAAATTTTCTGAAGAGGAGGCGGAGCGTGTTGCAGACTATAATCGTGTAGCTGAGCTTCGGTATAGTTTAATTCCCCA
ACTTGAAGAAGAAATCAAACAGGATGAAGCCTCTTTAAATCAAAGAGATAACCGTCTCCTTCAAGAAGAAGTTGACGAGC
GATTGATTGCGCAAGTGGTAGCTAATTGGACAGGGATTCCTGTGCAAAAAATGCTAGAAGGGGAAGCTGAGAAACTGTTA
ATTCTTGAAGAATCCTTAGAAGAACGTGTGGTAGGACAGCCTTTTGCAGTCTCTGCGGTTAGTGATTCTATTCGTGCTGC
ACGTGTAGGTTTAAATGATCCTCAACGTCCCTTAGGAGTCTTTTTATTTTTAGGGCCAACAGGGGTAGGAAAAACCGAGC
TTGCAAAAGCTCTTGCAGATCTTCTTTTCAATAAAGAGGAAGCTATGGTCCGCTTCGATATGTCAGAGTATATGGAAAAG
CATTCCATTTCCAAGCTTATAGGATCTTCTCCAGGGTATGTGGGTTATGAGGAAGGTGGGAGTCTTTCTGAGGCTCTTCG
ACGACGTCCCTATTCAGTAGTTCTCTTTGATGAGATAGAGAAAGCAGATAAGGAAGTTCTAAATATCCTTTTACAGGTTT
TTGATGATGGGATTCTTACGGATGGGAAAAAACGCAAAGTAAATTGTAAAAATGCCTTGTTTATCATGACATCAAATATA
GGTTCTCCAGAACTTGCAGATTATTGTTCAAAAAAAGGAAGTGAGCTTACGAAAGAAGCGATTCTTTCTGTAGTCTCTCC
AGTATTGAAAAGATACTTGAGCCCTGAATTTATGAACCGAATTGATGAGATACTTCCTTTTGTTCCATTAACGAAAGAAG
ATATCGTGAAAATAGTTGGCATTCAAATGCGAAGGATTGCCCAGAGATTAAAGGCACGGCGGATCAATTTATCTTGGGAT
GATTCTGTAATATTATTTCTTAGTGAACAGGGTTATGACAGTGCTTTCGGAGCCCGCCCTTTAAAACGTTTGATCCAACA
AAAAGTTGTGATCTTGCTTTCTAAGGCTTTGCTTAAAGGAGATATTAAACCTGATACATCGATTGAGTTGACGATGGCAA
AAGAGGTGCTCGTATTTAAAAAAGTGGAAACTCCTTCTTAG

Protein sequence :
MEKFSDAVSEALEKAFELAKSSKHTYVTENHLLLALLENTESLFYLVIKDIHGNPGLLNTAVKDALSREPTVVEGEVDPK
PSPGLQTLLRDAKQEAKTLGDEYISGDHLLLAFWSSNKEPFNSWKQTTKVSFKDLKNLITKIRRGNRMDSPSAESNFQGL
EKYCKNLTALAREGKLDPVIGRDEEIRRTIQVLSRRTKNNPMLIGEPGVGKTAIAEGLALRLIQGDVPESLKGKQLYVLD
MGALIAGAKYRGEFEERLKSVLKDVESGDGEHIIFIDEVHTLVGAGATDGAMDAANLLKPALARGTLHCIGATTLNEYQK
YIEKDAALERRFQPIFVTEPSLEDAVFILRGLREKYEIFHGVRITEGALNAAVLLSYRYIPDRFLPDKAIDLIDEAASLI
RMQIGSLPLPIDEKERELAALIVKQEAIKREQSPSYQEEADAMQKSIDALREELASLRLGWDEEKKLISGLKEKKNSLES
MKFSEEEAERVADYNRVAELRYSLIPQLEEEIKQDEASLNQRDNRLLQEEVDERLIAQVVANWTGIPVQKMLEGEAEKLL
ILEESLEERVVGQPFAVSAVSDSIRAARVGLNDPQRPLGVFLFLGPTGVGKTELAKALADLLFNKEEAMVRFDMSEYMEK
HSISKLIGSSPGYVGYEEGGSLSEALRRRPYSVVLFDEIEKADKEVLNILLQVFDDGILTDGKKRKVNCKNALFIMTSNI
GSPELADYCSKKGSELTKEAILSVVSPVLKRYLSPEFMNRIDEILPFVPLTKEDIVKIVGIQMRRIAQRLKARRINLSWD
DSVILFLSEQGYDSAFGARPLKRLIQQKVVILLSKALLKGDIKPDTSIELTMAKEVLVFKKVETPS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 8e-97 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB NP_224352.1 Clp protease ATPase VFG2084 Protein 1e-99 41
clpB NP_224352.1 Clp protease ATPase VFG2076 Protein 9e-114 41