Gene Information

Name : orf15 (jhp0477)
Accession : NP_223195.1
Strain : Helicobacter pylori J99
Genome accession: NC_000921
Putative virulence/resistance : Virulence
Product : cag island protein
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG3504
EC number : -
Position : 523548 - 525116 bp
Length : 1569 bp
Strand : -
Note : similar to H. pylori 26695 gene HP0528

DNA sequence :
ATGGGGCAGGCATTTTTTAAAAAAATTGTTGGCTGTTTCTGTCTTGGTTATTTATTTTTATCTAGCGCAATAGAAGCAGT
AGCACTTGACATTAAGAATTTTAATCGTGGTAGGGTGAAAGTGGTGAATAAGAAGATTGCTTATTTGGGAGATGAAAAAC
CTATTACGATTTGGACTTCATTAGACAATGTTACCGTGATCCAACTTGAAAAAGATGAAACTATTTCTTACATCACAACA
GGTTTCAATAAAGGTTGGAGTATTGTGCCTAATTCTAATCATATATTCATTCAACCTAAATCGGTAAAAAGTAATCTCAT
GTTTGAAAAAGAAGCAGTGAATTTTGCCCTAATGACAAGAGATTACCAAGAATTTTTAAAGACAAAAAAACTTATCGTAG
ATGCGCCTGACCCTAAAGAATTAGAAGAACAAAAAAAAGCTCTAGAAAAAGAAAAAGAAGCTAAAGAACAGGCGCAAAAG
GCACAAAAAGATAAAAGAGAAAAAAGAAAGGAGGAGCGTGCAAAAAATAGAGCCAATTTAGAAAATCTCACTAACGCTAT
GAGTAACCCACAAAATTTGAGCAATAACAAAAATCTTAGCGAATTGATCAAGCAACAGAGAGAAAATGAATTAGACCAAA
TGGAACGACTAGAGGACATGCAAGAGCAGGCTCAAGCTAACGCACTCAAACAAATTGAAGAGCTCAACAAGAAACAAGCT
GAAGAGGCAGTTAGGCAAAGAGCCAAGGATAAAATCAGTATTAAGACAGATAAATCTCAAAAAAGCCCCGAGGATAACTC
CATAGAATTATCTCCTAGCGATAGCGCTTGGAGGACTAATCTTGTTGTGCGGACCAATAAAGCCTTGTATCAATTCATTT
TGAGGATAGCCCAAAAAGACAATTTTGCTTCAGCGTATCTAACAGTCAAATTAGAATACCCACAAAGACACGAAGTCTCT
AGCGTTATTGAAGAGGAATTAAAAAAGAGAGAAGAAGCAAAGAGGCAGAGAGAATTGATCAAGCAAGAAAATCTCAACAC
CACAGCCTACATCAATAGAGTAATGATGGCGAGCAATGAACAGATTATCAACAAAGAAAAAATAAGAGAAGAAAAACAAA
AAATTATACTAGATCAAGCAAAGGCGCTAGAGACCCAATATGTGCATAATGCGTTAAAAAGAAACCCTGTGCCTAGAAAC
TACAATTACTACCAAGCGCCTGAAAAACGCTCTAAACATATTATGCCCTCTGAAATTTTTGATGATGGCACATTCACTTA
TTTTGGTTTCAAAAACATCACTCTCCAACCTGCTATTTTTGTGGTTCAACCTGATGGGAAATTGAGCATGACTGATGCCG
CCATTGATCCTAACATGACTAATTCAGGATTGAGATGGTATAGAGTTAATGAAATTGCAGAGAAGTTTAAGCTCATTAAA
GACAAAGCCCTTGTAACAGTGATCAATAAAGGCTATGGGAAAAATCCATTGACAAAAAATTACAATATCAAAAACTATGG
TGAATTGGAGCGTGTGATTAAAAAGCTCCCTCTTGTCAGAGATAAATAA

Protein sequence :
MGQAFFKKIVGCFCLGYLFLSSAIEAVALDIKNFNRGRVKVVNKKIAYLGDEKPITIWTSLDNVTVIQLEKDETISYITT
GFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTRDYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQK
AQKDKREKRKEERAKNRANLENLTNAMSNPQNLSNNKNLSELIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQA
EEAVRQRAKDKISIKTDKSQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKDNFASAYLTVKLEYPQRHEVS
SVIEEELKKREEAKRQRELIKQENLNTTAYINRVMMASNEQIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRN
YNYYQAPEKRSKHIMPSEIFDDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIK
DKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
orf15 NP_223195.1 cag island protein Virulence cag PAI Protein 0.0 100
HP0528 BAD13807.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD13889.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD13834.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cagX YP_005774541.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 NP_207324.1 cag pathogenicity island protein (cag8) Virulence cag PAI Protein 0.0 99
cagX AGC69795.1 cag pathogenicity island protein X Virulence cag PAI Protein 0.0 99
cag8 AAR03891.1 Cag8 Virulence cag PAI Protein 0.0 99
HP0528 BAD13999.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD14027.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD13916.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag8 AAR03863.1 Cag8 Virulence cag PAI Protein 0.0 99
HP0528 BAD14053.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag8 AAR03952.1 Cag8 Virulence cag PAI Protein 0.0 99
cagX YP_005777272.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag8 AAR03921.1 Cag8 Virulence cag PAI Protein 0.0 99
cagX YP_003728736.1 cag pathogenicity island protein X Virulence cag PAI Protein 0.0 99
cag-X AAF80199.1 Cag-X Virulence cag PAI Protein 0.0 99
HP0528 BAD13780.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
HP0528 BAD13861.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
cagX YP_005779062.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
HP0528 BAD13944.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
cagX YP_005775731.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
HP0528 BAD13971.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
orf15 NP_223195.1 cag island protein VFG0288 Protein 0.0 99