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Name : orf13/14 (jhp0476) Accession : NP_223194.1 Strain : Helicobacter pylori J99 Genome accession: NC_000921 Putative virulence/resistance : Virulence Product : cag island protein Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG2948 EC number : - Position : 518074 - 523533 bp Length : 5460 bp Strand : - Note : similar to H. pylori 26695 gene HP0527 DNA sequence : ATGAATGAAGAAAACGATAAACTTGAAACTTCTAAAAAAGCCCAACAAGATTCACCCCAAGATCTATCTAATGAAGAAGC AACAGAAGCCAATCATTTTGAAGATCTTTTAAAAGAATCCACAGAAAGCTCAGACAATCATCTTGACAACCCCACAGAAA CTAAAACCCATTTTGATGAAGACAAGCTAGAAGAAACCCAAACTCAAATGGATTCTGGAGGTAATGAAACTTCAGAATCT AGCAATGGCAGTCTAGCAGACAAGTTATTCAAGAAAGCCAGAAAATTAGTTGATGATAAAAGACCTTTCACTCAGCAAAA GAGTTTAGATGAAGAAACCCAAAAACTGAACGAAGAAGACGATCAAGAAAATAATGAGCATCAAGAAGAAACTCAAACGG ACTTGATTGATGATGAAACTTCTGAAAAAACCCAACAAGATTCACCCCAAGATCTATCTAATGAAGAAGCAACAGAAGCC AATCATTTTGAAGATCTTTTAAAAGAATCCACAGAAAGTTCAGATAATCATCTTGACAACCCCACAGAAAGCTCAGACAA TCATCTTGACAACCCCACAGAAACTAAAACCCAAGAAACTAAAACCCATTTTGATGAAGACAAGCCAGAAGAAATAACTG ACGACTCTAACGATCAAGAGATTATCAAAGGAAGCAAAAAGAAATACATTATTGGCGGCATTGTAGTCGCTGTTCTTATC GTGATTATTTTATTTTCTAGAAGCATTTTTCACTACTTTGTACCTTTGGAAGATAAAAGCTCTCGTTTTAGCAAAGACAG GAATCTTTATGTCAATGATGAAATCCAAATAAGGCAAGAGTATAACCGATTGCTGAAAGAACGGAATGAAAAAGGCAATA TGATCGATAAGAATCTTTTCTTCAATGACGATCCCAATAGAACCTTATACAACTATTTGAATATTGCAGAAATTGAGGAC AAAAACCCATTGAGAGCCTTTTATGAATGTATTAGTAATGGTGGCAACTATGAAGAATGTTTGAAGCTTATCAAAGACAA AAAACTTCAAGATCAGATGAAAAAGACTCTAGAGGCTTATAATGACTGCATCAAAAATGCCAAAACTGAAGAAGAAAGGA TCAAGTGTTTAGATTTAATCAAAGATGAAAACCTGAAAAAAAGCTTACTGAACCAACAAAAAGTTCAAGTGGCTCTAGAT TGTTTGAAAAACGCTAAAACCGATGAAGAACGGAAAGAGTGCCTAAAACTCATAAATGACCCTGAGATTAGAGAGAAATT CCGTAAGGAATTAGAGCTTCAAAAAGAGCTTCAAGAGTATAAGGATTGTATCAAAAACGCCAAAACAGAAGCTGAGAAAA ACGAATGCTTGAAAGGCTTGTCTAAAGAAGCCATAGAAAGATTGAAACAACAAGCGCTAGATTGTTTGAAAAACGCTAAA ACCGATGAAGAACGGAAAGAGTGCTTAAAAAATATTCCCCAAGACTTGCAAAAAGAACTACTAGCTGATATGAGCGTTAA GGCTTACAAAGACTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAACAAGAATGCGAGAAATTACTCACGCCTGAAGCGA AAAAACTATTAGAGAATCAAGCGCTAGATTGTTTGAAAAACGCTAAAACCGATGAAGAACGGAAAGAGTGCTTGAAAAAT CTCCCTAAAGACTTACAAAGCGATATTTTAGCTAAAGAGAGCCTGAAAGCTTATAAAGACTGCGCATCTCAAGCCAAAAC TGAAGCTGAAAAAAAAGAATGCGAGAAATTACTCACGCCTGAAGCGAAAAAACTTTTAGAAGAAGAAGCCAAAGAGAGCG TTAAGGCTTATTTGGATTGCGTATCTCAGGCCAAAACTGAAGCTGAAAAAAAAGAATGCGAGAAATTGCTCACACCTGAA GCGAAAAAAAAGTTAGAAGAAGCCAAAAAGAGCGTTAGAGCTTATTTGGATTGCGTATCAAAAGCCAAAAACGAAGCTGA AAGAAAAGAATGCGAGAAATTACTCACGCCTGAAGCGAAAAAACTATTAGAGAATCAAGCGCTAGATTGTTTGAAAAACG CTAAAACCGATGAAGAACGGAAAGAGTGCTTGAAAGATCTCCCTAAAGACTTACAGAAAAAGGTTTTAGCCAAAGAGAGT GTTAGGGTTTATTTGGATTGCGTATCAAAAGCCAAAAACGAAGCTGAAAGAAAAGAATGCGAGAAATTGCTCACCCCTGA AGCGAGAAAGCTATTAGAAGAAGCTAAGAAGAGCGTTAAGGCTTACAAAGACTGCGTTTTAAGAGCTAGGAATGAAAAAG AGAAACAAGAATGCGAGAAATTACTCACGCCTGAAGCGAGGAAACTATTAGAAGAATCTAAAAAAAGCGTTAAGGCTTAT TTGGATTGCGTATCAAAAGCCAAAAACGAAGCTGAAAGAAAAGAATGCGAGAAATTGCTCACCCCTGAAGCGAGAAAGCT ATTAGAAGAAGCTAAAGAGAGTGTTAAGGCTTACAAAGACTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAACAAGAAT GCGAGAAATTACTCACGCCTGAAGCGAGGAAACTATTAGAAGAATCTAAAAAAAGCGTTAAGGCTTATTTGGATTGCGTA TCAAAAGCCAAAAACGAAGCTGAAAGAAAAGAATGCGAGAAATTGCTCACCCCTGAAGCGAGAAAGCTATTAGAAGAAGC TAAAGAGAGTGTTAAGGCTTACAAAGACTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAACAAGAATGCGAGAAATTAC TCACGCCTGAAGCGAAAAAACTATTAGAGAATCAAGCGCTAGATTGTTTGAAAAACGCTAAAACCGAAGCTGAGAAAAAA AGGTGTGTCAAAGATCTCCCTAAAGACTTACAGAAAAAGGTTTTAGCCAAAGAGAGTGTTAGGGTTTATTTGGATTGCGT ATCAAAAGCCAAAAACGAAGCTGAAAGAAAAGAATGCGAGAAATTGCTCACCCCTGAAGCGAGAAAGCTATTAGAAGAAG CTAAAGAGAGTGTTAAGGCTTACAAAGACTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAACAAGAATGCGAGAAATTA CTCACCCCTGAAGCTAGGAAACTATTAGAGCAAGAAGTTAAAAAGAGCGTTAAGGCTTATTTAGACTGCGTTTCAAGAGC TAGGAATGAAAAAGAGAAACAAGAATGCGAGAAATTACTCACGCCTGAAGCGAGGAAACTTTTAGAGAATCAAGCGCTAG ATTGTTTGAAAAACGCTAAAACCGAAGCTGAGAAAAAAAGGTGTGTCAAAGATCTCCCTAAAGACTTGCAGAAAAAGGTT TTAGCTAAAGAGAGCGTTAAGGCTTATTTAGACTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAA GTTGCTCACGCCTGAAGCGAGAAAACTATTAGAAGAATCTAAAAAAAGCGTTAAGGCTTATTTGGATTGCGTATCAAAAG CCAAAAACGAAGCTGAAAAAAAAGAATGCGAGAAATTGCTCACACCTGAAGCGAGAAAGCTATTAGAAGAAGCTAAAGAG AGTGTTAAGGCTTACAAAGACTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAACAAGAATGCGAGAAACTACTCACCCC TGAAGCGAGGAAACTATTAGAGCAAGAAGTTAAAAAGAGCGTTAAGGCTTATTTAGACTGTGTATCAAGAGCTAGGAATG AAAAAGAGAAACAAGAATGCGAGAAATTACTCACCCCTGAAGCGAGGAAATTTTTAGAGAAACAGCGCCAACAAAAAGAT AAAGCGATAAAGGATTGCTTGAAAAACGCCGATCCTAACGACAGAGCGGCTATCATGAAGTGTTTGGATGGTTTGAGCGA TGAAGAGAAGCTCAAATACCTGCAAGAAGCCAGAGAAAAGGCTGTCTTGGATTGTTTGAAAACGGCTAGGACCGATGAAG AAAAAAGGAAATGCCAAAACCTTTATAGCGATTTGATCCAAGAAATCCAAAATAAAAAGGCACAGAACAAACAAAATCAA TTGAGTAAAACAGAAAGGTTGCATCAAGCAAGCGAGTGCTTGGATAACTTAGATGACCCTACTGATCAAGAAGCCATAGA GCAATGTTTAGAGGGATTGAGCGATAGCGAAAGGGCGCTAATTCTAGGAATCAAACGACAAGCTGATGAAGTGGATCGGA TTTATAGCGATCTAAGAAGCCGCAAAACCTTTGATAACATGGCGGCTAAAGGTTATCCATTGTTACCAATGGATTTTAAA AATGGTGGCGATATTGCTACTATTAACGCCACTAATGTTGATGCGGACAAAATAGCTAGCGATAATCCTATTTATGCTTC CATAGAGCCTGATATTACTAAGCAATACGAAACAGAGAAAACCATTAAGGATAAGAGTTTAGAAGCTAAATTAGCTAAGG CTTTAGGTGGCGATAAGAAAGATGACGATAAAGAAAAAGGTAAAAAACCCACAGCAGAAACTAAAGCAGAAAGCAATAAG ATAGACAAAGATGTCGCAGAAACTGCCAAAAATATCAGCGAAATCGCTCTTAAGAACAAAAAAGAAAAGAGTGGGGATTT TGTAGATGAAAATGGTAATCCCATTGATGATAAAAAGAAAGAAGAAAAACAAGATGAAACAAGCCCTGTCAAACAGGCCT TTATAGGCAAGAGTGATCCCACATTTGTTTTAGCACAATACACTCCCATTGAAATCACTCTGACTTCTAAAGTAGATGCC ACTCTCACGGGTATAGTGAGTGGGGTTGTAGCCAAAGATGTATGGAACATGAACGGCACTATGATCTTATTAGACAAAGG CACTAAGGTGTATGGGAATTATCAAAGCGTGAAAGGTGGCACGCCTATTATGACTCGTTTAATGATAGTCTTTACTAAAG CTATTACGCCTGATGGGGTGATTATACCTCTAGCAAACGCTCAAGCAGCAGGCATGCTGGGTGAAGCAGGGGTAGATGGC TATGTGAATAATCACTTCATGAAGCGCATAGGCTTTGCTGTGATAGCAAGCGTGGTTAATAGCTTCTTGCAAACTGCGCC TATCATAGCCCTAGATAAACTCATAGGTCTTGGCAAAGGCAGAAGTGAAAGGACACCTGAATTTAATTACGCTTTGGGTC AAGCTATCAATGGCAGTATGCAAAGTTCAGCTCAGATGTCTAATCAAATTCTAGGGCAACTGATGAATATCCCCCCAAGT TTTTACAAAAATGAGGGCGATAGCATTAAGATTCTCACCATGGACGATATTGATTTTAGTGGCGTGTATGATGTTAAAAT TACCAACAAATCTGTGGTAGATGAAATTATCAAACAAAGCACCAAAACTTTGTCTAGAGAACATGAAGAAATCACCACAA GCCCCAAAGGTGGCAATTGA Protein sequence : MNEENDKLETSKKAQQDSPQDLSNEEATEANHFEDLLKESTESSDNHLDNPTETKTHFDEDKLEETQTQMDSGGNETSES SNGSLADKLFKKARKLVDDKRPFTQQKSLDEETQKLNEEDDQENNEHQEETQTDLIDDETSEKTQQDSPQDLSNEEATEA NHFEDLLKESTESSDNHLDNPTESSDNHLDNPTETKTQETKTHFDEDKPEEITDDSNDQEIIKGSKKKYIIGGIVVAVLI VIILFSRSIFHYFVPLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIAEIED KNPLRAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTEEERIKCLDLIKDENLKKSLLNQQKVQVALD CLKNAKTDEERKECLKLINDPEIREKFRKELELQKELQEYKDCIKNAKTEAEKNECLKGLSKEAIERLKQQALDCLKNAK TDEERKECLKNIPQDLQKELLADMSVKAYKDCVSRARNEKEKQECEKLLTPEAKKLLENQALDCLKNAKTDEERKECLKN LPKDLQSDILAKESLKAYKDCASQAKTEAEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQAKTEAEKKECEKLLTPE AKKKLEEAKKSVRAYLDCVSKAKNEAERKECEKLLTPEAKKLLENQALDCLKNAKTDEERKECLKDLPKDLQKKVLAKES VRVYLDCVSKAKNEAERKECEKLLTPEARKLLEEAKKSVKAYKDCVLRARNEKEKQECEKLLTPEARKLLEESKKSVKAY LDCVSKAKNEAERKECEKLLTPEARKLLEEAKESVKAYKDCVSRARNEKEKQECEKLLTPEARKLLEESKKSVKAYLDCV SKAKNEAERKECEKLLTPEARKLLEEAKESVKAYKDCVSRARNEKEKQECEKLLTPEAKKLLENQALDCLKNAKTEAEKK RCVKDLPKDLQKKVLAKESVRVYLDCVSKAKNEAERKECEKLLTPEARKLLEEAKESVKAYKDCVSRARNEKEKQECEKL LTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKQECEKLLTPEARKLLENQALDCLKNAKTEAEKKRCVKDLPKDLQKKV LAKESVKAYLDCVSRARNEKEKKECEKLLTPEARKLLEESKKSVKAYLDCVSKAKNEAEKKECEKLLTPEARKLLEEAKE SVKAYKDCVSRARNEKEKQECEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKQECEKLLTPEARKFLEKQRQQKD KAIKDCLKNADPNDRAAIMKCLDGLSDEEKLKYLQEAREKAVLDCLKTARTDEEKRKCQNLYSDLIQEIQNKKAQNKQNQ LSKTERLHQASECLDNLDDPTDQEAIEQCLEGLSDSERALILGIKRQADEVDRIYSDLRSRKTFDNMAAKGYPLLPMDFK NGGDIATINATNVDADKIASDNPIYASIEPDITKQYETEKTIKDKSLEAKLAKALGGDKKDDDKEKGKKPTAETKAESNK IDKDVAETAKNISEIALKNKKEKSGDFVDENGNPIDDKKKEEKQDETSPVKQAFIGKSDPTFVLAQYTPIEITLTSKVDA TLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQSVKGGTPIMTRLMIVFTKAITPDGVIIPLANAQAAGMLGEAGVDG YVNNHFMKRIGFAVIASVVNSFLQTAPIIALDKLIGLGKGRSERTPEFNYALGQAINGSMQSSAQMSNQILGQLMNIPPS FYKNEGDSIKILTMDDIDFSGVYDVKITNKSVVDEIIKQSTKTLSREHEEITTSPKGGN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| orf13/14 | NP_223194.1 | cag island protein | Virulence | cag PAI | Protein | 0.0 | 100 |
| HP0527 | BAD13915.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 86 |
| HP0527 | BAD13860.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 84 |
| cagY | YP_005775730.1 | cag pathogenicity island protein Y VirB10-like protein | Virulence | cag PAI | Protein | 0.0 | 84 |
| HP0527 | BAD13888.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 82 |
| HP0527 | BAD13998.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 81 |
| HP0527 | BAD13970.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 78 |
| cagY | YP_003728737.1 | cag pathogenicity island protein Y | Virulence | cag PAI | Protein | 0.0 | 78 |
| HP0527 | BAD14052.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 78 |
| HP0527 | NP_207323.1 | cag pathogenicity island protein (cag7) | Virulence | cag PAI | Protein | 0.0 | 78 |
| HP0527 | BAD13833.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 77 |
| cagY | YP_005777271.1 | cag pathogenicity island protein Y VirB10-like protein | Virulence | cag PAI | Protein | 0.0 | 77 |
| HP0527 | BAD14026.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 77 |
| cag-Y | AAF80198.1 | Cag-Y | Virulence | cag PAI | Protein | 0.0 | 77 |
| cagY | YP_005774542.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 77 |
| HP0527 | BAD13779.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 76 |
| cagY | YP_005779063.1 | cag island protein | Virulence | cag PAI | Protein | 0.0 | 76 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| orf13/14 | NP_223194.1 | cag island protein | VFG0287 | Protein | 0.0 | 78 |
