Gene Information

Name : virD4 (jhp0473)
Accession : NP_223191.1
Strain : Helicobacter pylori J99
Genome accession: NC_000921
Putative virulence/resistance : Virulence
Product : cag island protein, DNA transfer protein
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG3505
EC number : -
Position : 514088 - 516334 bp
Length : 2247 bp
Strand : -
Note : similar to H. pylori 26695 gene HP0524

DNA sequence :
ATGGAAGACTTTTTGTATAACACCTTATATTTCATAGAGGATTATAAGTTGGTTGTTATTTTTAGTTTCATAGGGTTAAT
AGCGTTATTTTTCCTCTACAAATTCATAAAAACTCAAAAAAAGGTTTTTAAAGATAAAGCTAACCAGCCTCAAAAGAAAA
AAAGCTTTAAAGAAATCATTATAGATGGGCTGAAAGAAAGGGTTAAAACCTTTGGCTTTTGGTTGCAAGCTATACTATTA
CTATCCTATTCTTTTATCACATCAGGGTTATTTTTCTTGATTCTCTTAGGTAATTTTTATGATGATAATAGATTGCCTGA
GAGCGATGATGATCTTTTTGATATATGGGTCTATGCGATACAAGATTTTCCTGCATACTATTTTAAGGCACTCACTTTTA
GCTCGCTCAAGATTTATGGGTTCAATATATCCTTAGTCGTATATAGTTCTATTTTATGCTCTTATATATTCATTACCTTT
TTTGTGTGGTTCTTAAAATACTTAACTCGGACTAGGGACATAGGAGCGAATAAAAAAGTTGATGATCTCTTTGGTAGCGC
GAGTTGGGAAACTGAAGAGAAAATGATCAAAGCCAAGCTTATCACACCCAACAATAAAAAACGCGCCTTTGACAAACGAG
AGGTTATTGTAGGCAGGCGTGGCTTAGGGGATTTTATCGCTTACGCAGGACAGGCGTTTATTGGCTTGATTGCTCCTACT
AGGAGCGGTAAGGGTGTGGGTTTCATCATGCCCAATATGATCAATTACCCTCAAAATATCGTTGTGTTTGATCCTAAGGC
TGACACTATGGAAACTTGCGGGAAAATCAGAGAAAAACGCTTCAACCAAAAAGTGTTCATCTATGAACCTTTCTCCTTAA
AAACACACCGATTTAATCCTTTCGCTTATGTGGATTTTGGTAATGATGTGGTTTTGACTGAAGACATACTCTCTCAAATT
GACACACGCCTAAAAGGGCATGGCATGGTGGCTAGTGGAGGGGATTTTTCCACTCAAATCTTTGGATTGGCTAAGTTGGT
GTTCCCTGAAAGACCTAATGAAAAAGATCCTTTTTTTAGCAATCAGGCGCGAAACCTTTTTGTCATCAATTGCAATATTT
ATAGGGATCTCATGTGGACTAAAAAGGGGCTTGAGTTTGTCAAAAGAAAAAAAATCATCATGCCTGAAACCCCCACGATG
TTTTTCATAGGTTCTATGGCAAGCGGTATCAACTTGATTGATGAAGACACAAACATGGAAAAAGTCGTGTCTTTAATGGA
ATTTTTTGGAGGTGAAGAAGATAAGAGTGGCGACAATCTAAGAGCGCTTAGTCCTGCCACTAGAAACATGTGGAATAACT
TCAAGACAATGGGTGGCGCTAAAGAAACTTACAGCTCGGTTCAAGGGGTCTATACATCAGCGTTTGCGCCTTACAATAAC
GCCATGATCAGGAATTTCACGAGCGCTAATGATTTTGATTTCAGGCGTTTAAGGATCGATGCAGTGAGTATTGGTGTGAT
CGCTAATCCTAAAGAAAGCACTATTGTTGGACCGATATTAGAGCTGTTTTTCAACGTGATGATTTATAGCAATTTGATTC
TGCCAATCCATGATCCACAATGCAAAAGAAGCTGCTTGATGCTCATGGATGAATTTACGCTCTGTGGCTATTTAGAGACC
TTTGTTAAAGCGGTAGGGATCATGGCAGAATACAACATGCGCCCCGCTTTTGTGTTTCAAAGTAAGGCGCAATTAGAAAA
CGACCCCCCACTTGGTTATGGTAGGAATGGCGCTAAGACTATTTTAGACAACCTTTCTTTGAATATGTATTATGGGATCA
ACAACGATAACTACTATGAACATTTTGAAAAGCTTTCTAAAGTGTTAGGGAAATACACAAGGCAAGATGTGAGCCGGAGC
ATTGATGATAATACGGGTAAGACCAACACTTCTATCAGCAACAAGGAGCGGTTTTTGATGACCCCTGATGAATTGATGAC
TATGGGCGATGAGCTTATCATTTTAGAAAACACGCTCAAACCCATCAAGTGCCACAAGGCGCTTTACTATGATGATCCCT
TCTTCACCGATGAGCTCATTAAGGTGAGTCCAAGCTTGAGCAAGAAATACAAATTGGGGAAAGTGCCTAATCAAGCAACA
TTTTATGATGACTTGCAAGCCGCTAAAACCAGAGGCGAATTGAGCTATGATAAATCTTTAGTGCCTGTGGGTTCAAGCGA
ACTGTGA

Protein sequence :
MEDFLYNTLYFIEDYKLVVIFSFIGLIALFFLYKFIKTQKKVFKDKANQPQKKKSFKEIIIDGLKERVKTFGFWLQAILL
LSYSFITSGLFFLILLGNFYDDNRLPESDDDLFDIWVYAIQDFPAYYFKALTFSSLKIYGFNISLVVYSSILCSYIFITF
FVWFLKYLTRTRDIGANKKVDDLFGSASWETEEKMIKAKLITPNNKKRAFDKREVIVGRRGLGDFIAYAGQAFIGLIAPT
RSGKGVGFIMPNMINYPQNIVVFDPKADTMETCGKIREKRFNQKVFIYEPFSLKTHRFNPFAYVDFGNDVVLTEDILSQI
DTRLKGHGMVASGGDFSTQIFGLAKLVFPERPNEKDPFFSNQARNLFVINCNIYRDLMWTKKGLEFVKRKKIIMPETPTM
FFIGSMASGINLIDEDTNMEKVVSLMEFFGGEEDKSGDNLRALSPATRNMWNNFKTMGGAKETYSSVQGVYTSAFAPYNN
AMIRNFTSANDFDFRRLRIDAVSIGVIANPKESTIVGPILELFFNVMIYSNLILPIHDPQCKRSCLMLMDEFTLCGYLET
FVKAVGIMAEYNMRPAFVFQSKAQLENDPPLGYGRNGAKTILDNLSLNMYYGINNDNYYEHFEKLSKVLGKYTRQDVSRS
IDDNTGKTNTSISNKERFLMTPDELMTMGDELIILENTLKPIKCHKALYYDDPFFTDELIKVSPSLSKKYKLGKVPNQAT
FYDDLQAAKTRGELSYDKSLVPVGSSEL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
virD4 NP_223191.1 cag island protein, DNA transfer protein Virulence cag PAI Protein 0.0 100
HP0524 BAD13995.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13940.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005774545.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13912.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13885.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13803.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag-beta AAF80195.1 Cag-beta Virulence cag PAI Protein 0.0 99
cag5 YP_005779066.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03947.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD13776.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005777268.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03858.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD13830.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 NP_207320.1 cag pathogenicity island protein (cag5) Virulence cag PAI Protein 0.0 99
HP0524 BAD14023.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13967.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_003728740.1 cag pathogenicity island protein beta Virulence cag PAI Protein 0.0 99
cag5 AAR03887.1 Cag5 Virulence cag PAI Protein 0.0 99
cag5 AAR03916.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD14049.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
cag5 YP_005775727.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
HP0524 BAD13857.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
virD4 NP_223191.1 cag island protein, DNA transfer protein VFG0284 Protein 0.0 99