Gene Information

Name : orf8 (jhp0471)
Accession : NP_223189.1
Strain : Helicobacter pylori J99
Genome accession: NC_000921
Putative virulence/resistance : Virulence
Product : cag island protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 511642 - 513087 bp
Length : 1446 bp
Strand : +
Note : similar to H. pylori 26695 gene HP0522

DNA sequence : 
ATGTTTAGAAAACTAGCAACCTCTGTATCGCTCATAAGCCTACTAATCTCCAACGCTCTTTATGCTAAAGAAATAAGTGA
AGCCGATAAGGTCATTAAGGCCACTAAAGAAACTAAAGAGACCAAGAAAGAGGCTAAACGCCTCAAAAAAGAAGCTAAAC
AGCGCCAACAGATCCCTGATAATAAGAAACCTCAATATGTCTCTGTTGATGACACAAAAACTCAAGCGCTTTTTGATATA
TATGACACTTTGAATGTGAATGACAAAAGCTTTGGGGATTGGTTTGGTAATAGCGCTTTGAAAAACAAAACTTATCTCTA
CGCTATGGATCTATTGGATTATAACAACTACTTATCCATAGAAAACCCTATTATCAAAACAAGAGCGATGGGAACTTATG
CAGATCTGATTATCATCACAGGTTCGTTAGAACAAGTCAATGGGTATTACAATATTCTAAAAGCGCTCAACAAACGCAAC
GCTAAGTTTGTGTTAAAAATCAATGACAAAATACCTTATGCCCAAGCGACTTTTTTGAGAGTGCCAAAAAGAAGCGATCC
CAACGCCCACACGCTTGATAAGGGAGCGTCAATTGATGAAAGCAAGCTTTTTGAACAACAAAAGAAAATGTATTTCAACT
ACGCCAACGATGTGATCTGCAGACCCAACGATGAAGTGTGTTCGCCCCTAAGAGATGAAATGGTAGCTATGCCCACTAAC
GATAGCGTTACTCAAAAACCCAATATCATTGCTCCTTATAGCCTGTATAGACTAAAAGAGACAAATAACGCCAATGAAGC
CCAACCATCACCTTATGCCACTCAAACCGCTCCTGAAAACAGCAAAGAGAAGCTCATAGAAGAGCTAATCGCCAACTCCC
AACTCATAGCCAATGAAGAAGAGAGGGAAAAGAAACTCTTAGCAGAAAAAGAAAAACAAGAGACTGAATTGGCTAAATAC
AAGCTCAAAGATTTAGAAAATCAAAAGAAACTAAAAGCTTTAGAAGCAGAGTTGAAAAAGAAAAACACTAAGAAACCTAG
AGTAGTGGAAGTGCCTATTCCTCCTAAAACAAGTGATTCTGATGAAACAATGAGAGTTATCAAAGAAAAAGAAAACTATA
ATGGGTTATTAGTGGATAAAGAGACCACGATCAAAAGAAGCTATAAGGGGACTTTGATCAGTGAAAATTCTTACAGCAAA
AAAACACCCATCAACCTTGAGGACTTGAGAAGCTTAGAAGAAGAAATTAAGAGCTACTATGTCAAGTCTAATGGCTTGTG
TTACGCTAATGGCATTAACCTCTATGTAAAAATCAAAAACGATCCCTACAAAGAGGGAATGCTGTGTGGTTATGAGAGCG
TTCAAAAACTGCTTTCACCACTAAGGGACAAGCTCAAATACGACAAGCAGAAGTTACAAAAAGCGTTACTGAAAGATTTA
AAGTAA

Protein sequence : 
MFRKLATSVSLISLLISNALYAKEISEADKVIKATKETKETKKEAKRLKKEAKQRQQIPDNKKPQYVSVDDTKTQALFDI
YDTLNVNDKSFGDWFGNSALKNKTYLYAMDLLDYNNYLSIENPIIKTRAMGTYADLIIITGSLEQVNGYYNILKALNKRN
AKFVLKINDKIPYAQATFLRVPKRSDPNAHTLDKGASIDESKLFEQQKKMYFNYANDVICRPNDEVCSPLRDEMVAMPTN
DSVTQKPNIIAPYSLYRLKETNNANEAQPSPYATQTAPENSKEKLIEELIANSQLIANEEEREKKLLAEKEKQETELAKY
KLKDLENQKKLKALEAELKKKNTKKPRVVEVPIPPKTSDSDETMRVIKEKENYNGLLVDKETTIKRSYKGTLISENSYSK
KTPINLEDLRSLEEEIKSYYVKSNGLCYANGINLYVKIKNDPYKEGMLCGYESVQKLLSPLRDKLKYDKQKLQKALLKDL
K

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
orf8 NP_223189.1 cag island protein Virulence cag PAI Protein 4e-173 100
HP0522 BAD13910.1 cag pathogenicity island protein Virulence cag PAI Protein 4e-167 95
HP0522 NP_207318.1 cag pathogenicity island protein (cag3) Virulence cag PAI Protein 1e-167 95
cag3 AAR03914.1 Cag3 Virulence cag PAI Protein 1e-167 95
cag3 AAR03854.1 Cag3 Virulence cag PAI Protein 1e-167 95
cag3 YP_003728744.1 cag pathogenicity island protein delta Virulence cag PAI Protein 5e-167 94
cag3 AGC69793.1 cag pathogenicity island protein 3 Virulence cag PAI Protein 3e-167 94
cag-delta AAF80193.1 Cag-delta Virulence cag PAI Protein 4e-166 94
cag3 YP_005779068.1 cag pathogenicity island protein Virulence cag PAI Protein 5e-167 94
HP0522 BAD13774.1 cag pathogenicity island protein Virulence cag PAI Protein 3e-167 94
HP0522 BAD13938.1 cag pathogenicity island protein Virulence cag PAI Protein 3e-166 94
HP0522 BAD13801.1 cag pathogenicity island protein Virulence cag PAI Protein 2e-166 94
HP0522 BAD13883.1 cag pathogenicity island protein Virulence cag PAI Protein 1e-166 94
HP0522 BAD14047.1 cag pathogenicity island protein Virulence cag PAI Protein 1e-166 94
cag3 YP_005775725.1 cag pathogenicity island protein Virulence cag PAI Protein 4e-165 94
HP0522 BAD13828.1 cag pathogenicity island protein Virulence cag PAI Protein 7e-167 94
cag3 YP_005777266.1 cag pathogenicity island protein Virulence cag PAI Protein 4e-166 94
HP0522 BAD14021.1 cag pathogenicity island protein Virulence cag PAI Protein 5e-167 94
HP0522 BAD13855.1 cag pathogenicity island protein Virulence cag PAI Protein 3e-165 94
cag3 AAR03945.1 Cag3 Virulence cag PAI Protein 5e-166 94
HP0521 BAD13993.1 cag pathogenicity island protein Virulence cag PAI Protein 4e-164 94
HP0521 BAD13965.1 cag pathogenicity island protein Virulence cag PAI Protein 7e-164 94
cag3 YP_005774547.1 cag pathogenicity island protein Virulence cag PAI Protein 3e-166 93
cag3 AAR03885.1 Cag3 Virulence cag PAI Protein 2e-163 93

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
orf8 NP_223189.1 cag island protein VFG0282 Protein 5e-168 95