Gene Information

Name : tktA (jhp0337)
Accession : NP_223056.1
Strain : Helicobacter pylori J99
Genome accession: NC_000921
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 367766 - 369691 bp
Length : 1926 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGCAATTGAGTAACGCTGATTTAGAACGATTAAAAAGCATGGCGAACACGCTTCGCTTTTTGTGTGCGGACATGATAGA
TAAGGCTAATAGCGGGCATCCAGGCGTGTGTTTAGGGCTAGCTGATGTGATGGTGGTTTTAAGCTTGCACCTCAACCTAA
ACCCCACCAACCCTAAATGGCTCAATAGGGACAGGTTGGTTTTTAGCGGAGGGCATGCGAGCGCGTTAGTGTATAGTTTG
TTGCATTTGTGGGGCTTTGATTTGAGTTTAGACGATTTAAAGCGTTTCAGGCAATTACACTCTAAAACCCCAGGACACCC
TGAATTACACCACACCGAAGGCATTGAAATCACCACAGGCCCTTTAGGGCAAGGTTTTGCTAACGCTGTAGGCTTTAGCA
TGGCGAGCCAATACGCTCAAACCCTTTTAGATAAAGAGGCGATTTCTCATAAAGTCTATTGCTTGTGTGGGGATGGGGAT
TTGCAAGAAGGCATTAGTTATGAGAGCACTTCTTTAGCCGGGCACCTTCGCCTTGATAATCTCATTGTGATTTATGACAG
CAACCAGATCAGCATTGAAGGCGCTATTAATATTAGTTTTAGCGAACAGGTTAAAACACGCTTTTTAGCGCAAAATTGGG
AAGTGCTAGAATGCGATGGGCATGACTATCAAGCGATTCATAACGCTTTAGAAGAAGCCAAAAAATCCCATAAACCCACG
CTTTTAATCGCTCATACGATCATTGGTAAGGGGGCTATTGGCTTAGAGGGGAGTGAAAAAACGCATGGCTCGCCTTTAAG
TAAAGAAGTGTTGAAACAATCCAAAGAAAACGCTCAAATCAATCCTAACGAAAGCTTTATAATTAGCCCAAAAAACAAAA
TGCATTTTGAAGAAGTGAAAGTTAGGGGTATTAGTTTAGAAGCCTTATGGGAAAAGTCCTTAAGCCCTAAAACAAAAGAA
AAGATCCATGCGTTAAAGAATTTTGATTTTAACGCCATTAATTACCCCGCCTTTAAAAAAGGCGAATCTCTAGCCACGAG
AGTGAGTAACGGCATGATTTTAAACGCTATCGCTAAAGAATGCGAGGGCTTTTTAGGAGGGAGTGCGGATTTAGCCCCAT
CCAATAACACGCATTTGAAACACTCTGGCGATTTCCCTTTAGGGCAAAACCTGCATTTTGGGATCAGGGAGCATGCCATG
GGGGCTATCACTAACGCTTTAGCGGCGTATGGCTTGTTTGTGCCTTTTTGCGCGACCTTTTTTGTGTTTAGCGATTATTT
AATGCCTAGCATTCGTTTGAGCGCTTTAATGAAATTAAAAGCCCTTTTTATCTTCACGCATGACAGCATTGGGGTGGGCG
AAGACGGGGCGACGCACCAGCCCATAGAGCAATTGAGCCATTTACGAGCCTTGCCGCATTTCTATGCTTTCAGGCCTAGC
GATGCTTTTGAAAATAAGGCTTGCATGCAAGTGGCATTAAGTTTGAACGCCCCTAGCGCTCTTATTTTATCGCGCCAGAA
TTTGTCCGTGCTTGATGAGGTTTCTAAAGAGCAGGTTCTAAAAGGGGCGTATGTTAAACACCACTCTAAAGATCCCATTA
TCACGCTTGTTGCGAGCGGGAGCGAAGTCTCTTTAGCTTTAGAGAGCGCTAAGATTTTAGAGCGAGAAAATATTCCCACT
CAAGTAGTGAGCGCGCCATGCTTTGACTTGTTGGTAGAGCAAGATGAAAGCTATTTTAAAGAACTCTTTAAGGGTAAAGT
CTTAGTGATTGAAGCGAGCCGCGCGATAGAGTGGTATCGTTTTGCGGATAAAATCATTGGCATGGATTCTTTTGGGAGCT
CAGCAAAGGGCGATAAACTCTTTGAAAAATTTGGCTTTAGCGTTGAAAACATTACCGCTCAAGCGAAAAGGTTACTCAAC
GCATGA

Protein sequence :
MQLSNADLERLKSMANTLRFLCADMIDKANSGHPGVCLGLADVMVVLSLHLNLNPTNPKWLNRDRLVFSGGHASALVYSL
LHLWGFDLSLDDLKRFRQLHSKTPGHPELHHTEGIEITTGPLGQGFANAVGFSMASQYAQTLLDKEAISHKVYCLCGDGD
LQEGISYESTSLAGHLRLDNLIVIYDSNQISIEGAINISFSEQVKTRFLAQNWEVLECDGHDYQAIHNALEEAKKSHKPT
LLIAHTIIGKGAIGLEGSEKTHGSPLSKEVLKQSKENAQINPNESFIISPKNKMHFEEVKVRGISLEALWEKSLSPKTKE
KIHALKNFDFNAINYPAFKKGESLATRVSNGMILNAIAKECEGFLGGSADLAPSNNTHLKHSGDFPLGQNLHFGIREHAM
GAITNALAAYGLFVPFCATFFVFSDYLMPSIRLSALMKLKALFIFTHDSIGVGEDGATHQPIEQLSHLRALPHFYAFRPS
DAFENKACMQVALSLNAPSALILSRQNLSVLDEVSKEQVLKGAYVKHHSKDPIITLVASGSEVSLALESAKILERENIPT
QVVSAPCFDLLVEQDESYFKELFKGKVLVIEASRAIEWYRFADKIIGMDSFGSSAKGDKLFEKFGFSVENITAQAKRLLN
A

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 2e-106 42
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 2e-95 41