Gene Information

Name : clpB (jhp0249)
Accession : NP_222970.1
Strain : Helicobacter pylori J99
Genome accession: NC_000921
Putative virulence/resistance : Virulence
Product : heat shock protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 269487 - 272057 bp
Length : 2571 bp
Strand : +
Note : similar to H. pylori 26695 gene HP0264

DNA sequence :
ATGAATTTATTTGAAAAAATGACTGACCAATTGCATGAAACTTTAGACAGCGCGATCGCTTTAGCCTTACACCATAAAAA
CGCTGAAGTAACGCCCATGCACATGCTTTTTGCCATGCTCAATAACTCCCAAGGCATTCTCATTCAAGCCTTACAAAAAA
TGCCTGTGGATATTGAAGCTTTAAAACTTAGCGTTCAAAGCGAGTTGAATAAGTTCGCTAAAGTTTCACAAATCAGCAAG
CAAAACATCCAATTAAACCAAGCTCTAATCCAAAGTTTAGAAAACGCTCAAGGCTTGATGGCTAAAAGGGGCGATTCTTT
CATCGCTACCGATGCGTATCTTTTGGCGAATATGAATCTTTTTGAAAGCGTTCTAAAGCCTTATTTAGACACTAAGGAAT
TGCAAAAAACTTTAGAATCTTTAAGAAAAGGCAGGACTATCCAGGATAAAAACGACGATTCCAACTTGGAAAGTTTGGAA
AAATTTGGCATTGATTTGACGCAAAAAGCCCTAGAAAATAAGCTGGATCCCGTGATTGGAAGGGATGAAGAAATCATTCG
CATGATGCAAATTTTGATCAGAAAAACAAAAAATAACCCTATTTTACTGGGCGAGCCTGGAGTGGGGAAAACGGCTGTTG
TGGAAGGGTTAGCCCAACGCATTGTGAATAAGGAAGTGCCTAAAACGCTTTTAAACAAACGGGTTGTCGCTTTAGATTTG
AGCTTATTGGTGGCTGGGGCGAAATACAGAGGCGAGTTTGAAGAGCGCCTGAAAAAGGTGATTGAAGAAGTTAAAAAAAG
CGCGAATGTGATTTTATTCATTGATGAAATCCACACGATTGTGGGGGCTGGGGCTAGTGAGGGGGGCATGGATGCGGCCA
ATATTTTAAAACCCGCGCTCGCTAGGGGGGAATTGCACACGATTGGAGCGACCACTCTAAAAGAATACCGCAAGTATTTT
GAAAAAGACATGGCGCTACAAAGGCGTTTCCAACCCATTTTACTCAATGAGCCTAGCATCAATGAAGCTTTACAGATTTT
AAGGGGGTTGAAAGAAACTTTAGAAACGCACCATAATATCACTATCAATGACTCCGCGCTCATAGCGAGCGCTAAACTCT
CTAGCCGTTATATCACCGATAGGTTTTTACCCGATAAAGCGATTGATTTGATTGATGAGGGAGCGGCCCAATTAAAAATG
CAAATGGAATCAGAGCCGGCCAAACTCTCTAGCGTGAAGCGCTCCATTCAAAGACTAGAAATGGAAAAACAAGCCCTTGA
AATGGAAAACAAAGAGAGCAACCACAAACGCATGCAAGAAATCCTTAAAGAATTGAGCGATTTGAAAGAGGAAAAAATCC
AATTAGAAGCGCAATTTGAAAACGAAAAAGAAGTGTTTAAGGAAATTTCACGCTTGAAAATGGAAATGGAGGGCTTGAAA
AAAGAAGCCGAAAGGTTTAAACGCAATGGGGATTACCAGCAAGCGGCTGAAATTGAATACTCTAAAATCCCTGAAAAGGA
AAAGAAAGAAAAAGAATTGCAGCATAAATGGGAAACGATGCAACAAAACGGGGCGTTGTTGCAAAACGCTTTAACCGAAA
ACAACATCGCTGAGATCGTGAGCCAATGGACGCACATCCCGGTCCAAAAAATGCTCCAAAGCGAAAAAAATAGGGTTTTA
AACATTGAAAGCGAATTGCAAAAAAGGGTGGTGGGGCAAGAAAAAGCGCTCAAAGCGATCGCTAAAGCGATTAAAAGGAA
TAAGGCTGGGCTTAGCGATAGCAACAAGCCCATAGGGAGTTTCCTCTTTTTAGGGCCAACAGGCGTGGGTAAAACCGAGA
GCGCTAAAGCTTTGGCGCAATTCTTGTTTGATAGCGATAAAAATCTTATACGAATTGACATGAGCGAATACATGGAAAAG
CACGCTATCAGCCGTCTTATTGGGGCCGCTCCTGGGTATGTGGGCTATGAAGAAGGCGGGCAATTGACCGAAGCGGTGCG
CAGAAAACCTTATAGCGTAGTGTTATTAGATGAAGTGGAAAAAGCCCATCCGGATGTGTTTAACCTCTTGTTACAGGTTT
TAGATGAGGGGCATTTAACCGATAGTAAGGGCGTGAGGGTGGATTTCAAAAACACGATTTTGATTTTAACCAGCAATGTG
GCTAGCGGCGCGCTTTTAGAAGAGGATTTGAGTGAAGCCGATAAACAAAAAGCGATCAAAGAGAGCCTGAGACAATTCTT
CAAGCCGGAATTTTTAAACCGCTTAGATGAAATCATCTCCTTTAACGCCCTAGATAGTCATGCTATCATCAATATCGTGG
GGATACTCTTTGAAAACGTTCAAAAAAAAGCGCTTGAAAGGGGCATTAATATAACCCTAGACGAAAAAGCAAAAGAATTG
ATCGCCGAAGCGGGGTTTGACAGATTTTATGGCGCTAGACCCCTAAAACGCGCGCTCTATGAAATGGTAGAAGACAAGCT
CGCTGAACTCATTTTAGAGGATAAAATTAAAGAGAATGACAGCGTGGCGTTTGTGGTAGAAAATAACGAGATTGTGCCTA
AGATTAAGTGA

Protein sequence :
MNLFEKMTDQLHETLDSAIALALHHKNAEVTPMHMLFAMLNNSQGILIQALQKMPVDIEALKLSVQSELNKFAKVSQISK
QNIQLNQALIQSLENAQGLMAKRGDSFIATDAYLLANMNLFESVLKPYLDTKELQKTLESLRKGRTIQDKNDDSNLESLE
KFGIDLTQKALENKLDPVIGRDEEIIRMMQILIRKTKNNPILLGEPGVGKTAVVEGLAQRIVNKEVPKTLLNKRVVALDL
SLLVAGAKYRGEFEERLKKVIEEVKKSANVILFIDEIHTIVGAGASEGGMDAANILKPALARGELHTIGATTLKEYRKYF
EKDMALQRRFQPILLNEPSINEALQILRGLKETLETHHNITINDSALIASAKLSSRYITDRFLPDKAIDLIDEGAAQLKM
QMESEPAKLSSVKRSIQRLEMEKQALEMENKESNHKRMQEILKELSDLKEEKIQLEAQFENEKEVFKEISRLKMEMEGLK
KEAERFKRNGDYQQAAEIEYSKIPEKEKKEKELQHKWETMQQNGALLQNALTENNIAEIVSQWTHIPVQKMLQSEKNRVL
NIESELQKRVVGQEKALKAIAKAIKRNKAGLSDSNKPIGSFLFLGPTGVGKTESAKALAQFLFDSDKNLIRIDMSEYMEK
HAISRLIGAAPGYVGYEEGGQLTEAVRRKPYSVVLLDEVEKAHPDVFNLLLQVLDEGHLTDSKGVRVDFKNTILILTSNV
ASGALLEEDLSEADKQKAIKESLRQFFKPEFLNRLDEIISFNALDSHAIINIVGILFENVQKKALERGINITLDEKAKEL
IAEAGFDRFYGARPLKRALYEMVEDKLAELILEDKIKENDSVAFVVENNEIVPKIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 4e-99 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB NP_222970.1 heat shock protein VFG2076 Protein 3e-108 41