Gene Information

Name : hemC (jhp0222)
Accession : NP_222943.1
Strain : Helicobacter pylori J99
Genome accession: NC_000921
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 243536 - 244456 bp
Length : 921 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGGAAAAATTAGTGATTGGCTCTAGGGGGAGCGAATTGGCCTTATGGCAAGCGAATCACATTAAAGAACGCTTGAAAAA
AGAATGCTCTATGGAAAGCGAAATTCGAATCGTTAAAACCACAGGCGATAAGATTTTAGATGCACCTTTAAATAAGATTG
GCGGTAAGGGGCTATTCACTAAGGAATTAGAAGAATTGCTTTTAAAAGGCGCAATTGATTTGGCGGTGCATTCTTTAAAA
GATGTGCCGGTCGTGTTTGAAAAGGGGTTAGACTTGGCATGCATCACCAAAAGGGCTGATGTGAGGGACACTTTTTTGAG
CGTGAAATTCCCTGATTTGATGAGCTTACCTAAAGGGGCCAAGGTTGGCACGACTTCTTTAAGGCGCTCCATGCAGATCA
AATTCAAACGAAAAGATCTAGACACAGAAAGTTTAAGGGGGAATGTCCAAACCCGTTTGAAAAAGCTTGAATGCGGTGAA
TTTGACGCTATCATTTTGGCTGAAGCGGGGTTGTGCCGCTTAAACGTTCAAGGGGCGAAATACCGCAAGGCTTTTAGCGT
AAAAGAAATGATTCCTAGCATGGGTCAGGGGGCTTTAGGGGTAGAAATGCTCAAAAACCACAAGCATTTTATTACGCTTC
AAAAACTCAACAATGAAGAAAGCGCGTTTTGTTGCCATTTAGAAAGGGAATTTATCAAAGGGCTTAATGGGGGGTGTCAG
ATCCCTATTGGCGTGCATGCGAATTTAATGGGCGATGAGGTTAAAATCCGGGCGGTTTTGGGCTTGCCTAATGGGAAAGA
AGTCATTGCTAAAGAAAAGCAAGGGGATAAAACTAAAGCGTTTGATTTGGTTCAAGAGCTTTTAGAAGAATTTTTACAAA
GTGGGGCGAAAGAGATTTTAGAAAAGGCGCAGTTGTTTTAA

Protein sequence : 
MEKLVIGSRGSELALWQANHIKERLKKECSMESEIRIVKTTGDKILDAPLNKIGGKGLFTKELEELLLKGAIDLAVHSLK
DVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGAKVGTTSLRRSMQIKFKRKDLDTESLRGNVQTRLKKLECGE
FDAIILAEAGLCRLNVQGAKYRKAFSVKEMIPSMGQGALGVEMLKNHKHFITLQKLNNEESAFCCHLEREFIKGLNGGCQ
IPIGVHANLMGDEVKIRAVLGLPNGKEVIAKEKQGDKTKAFDLVQELLEEFLQSGAKEILEKAQLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-42 46
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-42 46