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Name : lysS (jhp0170) Accession : NP_222891.1 Strain : Helicobacter pylori J99 Genome accession: NC_000921 Putative virulence/resistance : Virulence Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 184746 - 186251 bp Length : 1506 bp Strand : + Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA DNA sequence : ATGTTTTCTAACCAATACATCCAACAACGCATCCATAAAGCCAATAGCTTGAGAGAAGAAGGCAAAAATCCTTATAAAAA TGGCTTGAAACGGAGCCTTACCAACGCCGCTTTTTTAGAAAAATACGCTTATGTTAAGGGTTTAGAAGAGCCTAAAGACA AAGAAAAATGCGAGAGCGTTGTAGGGAGGGTCAAGCTCTTGCGTTTAATGGGTAAGGCATGTTTTATTAAAATTGAAGAT GAAAGCGCGATTTTACAAGCTTATGTTTCGCAAAATGAATTGAATGATGAGTTTAAAAGCTTGAAAAAGCATTTAGAAGT GGGCGATATTGTGTTGGTGAAAGGTTTCCCTTTTGCTACCAAAACCGGTGAATTAAGCATTCATGCCCTAGAATTTCACA TTTTAAGCAAAACCATCGTGCCTTTGCCTGAGAAATTTCATGGACTGAGCGATATAGAATTGCGTTACCGCCAGCGCTAC TTGGATTTGATCGTCAATCCTGGCGTTAAAGATGTGTTTAAAAAGCGCAGTTTGATTGTCTCTAGCGTGCGGAAATTCTT TGAAATGGAAGGGTTTTTAGAAGTGGAAACCCCTATGATGCACCCCATTCCTGGCGGGGCGAACGCAAGGCCTTTCATCA CTTATCATAACGCCTTAGAAATTGAAAGGTATTTGAGAATCGCCCCAGAATTATACCTTAAACGCTTGATTGTGGGGGGT TTTGAAGCGGTGTTTGAAATCAATCGTAATTTCAGGAATGAGGGCATGGATCACAGCCATAACCCCGAATTTACGATGAT TGAGTTTTATTGGGCGTATCACACTTATGAAGATTTGATTGAACTCAGTAAGAGGTTGTTTGACTACTTGCTAAAGACTT TAAATTTAGATTCAAAAATCATTTATAACGATATGGAAGTGGATTTCAACCAAACGAGCGTGATTTCCTATTTGGACGCT TTAGAAACAATAGGGGGCATCAGTAAGGGCATTTTAGAAAAAGAAGACAGGCTTTTGGCTTATTTATTAGAGCAGGGCAT TAAAGTAGAGCCAAACCTCACTCATGGCAAATTGCTCGCTGAAGCGTTTGATCATTTTGTAGAGCATAAGCTCATTAACC CCACTTTTGTAACCGAATACCCTATTGAAATTAGCCCCCTAGCCAGACGCAACGATAGTAACCCTAATATTGCTGACAGG TTTGAATTGTTTATTGCAGGTAAAGAAATCGCTAATGGCTTTAGCGAGTTGAATGACCCTTTAGACCAACTAGAGCGCTT TAAAAATCAAGTGGCTGAAAAAGAAAAAGGCGATGAAGAAGCCCAATACATGGATGAAGATTATGTGTGGGCCCTAGCCC ATGAAATGCCCCCCACTGCAGGGCAAGGCATAGGCATTGACCGATTAGTGATGCTACTCACTGGAGCTAAAAGCATTAAA GATGTGATTTTATTCCCAGCGATGCGTCCTGTTAAAAACGATTTTAATGTTGAGGGTGAAGAATAA Protein sequence : MFSNQYIQQRIHKANSLREEGKNPYKNGLKRSLTNAAFLEKYAYVKGLEEPKDKEKCESVVGRVKLLRLMGKACFIKIED ESAILQAYVSQNELNDEFKSLKKHLEVGDIVLVKGFPFATKTGELSIHALEFHILSKTIVPLPEKFHGLSDIELRYRQRY LDLIVNPGVKDVFKKRSLIVSSVRKFFEMEGFLEVETPMMHPIPGGANARPFITYHNALEIERYLRIAPELYLKRLIVGG FEAVFEINRNFRNEGMDHSHNPEFTMIEFYWAYHTYEDLIELSKRLFDYLLKTLNLDSKIIYNDMEVDFNQTSVISYLDA LETIGGISKGILEKEDRLLAYLLEQGIKVEPNLTHGKLLAEAFDHFVEHKLINPTFVTEYPIEISPLARRNDSNPNIADR FELFIAGKEIANGFSELNDPLDQLERFKNQVAEKEKGDEEAQYMDEDYVWALAHEMPPTAGQGIGIDRLVMLLTGAKSIK DVILFPAMRPVKNDFNVEGEE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD66193.1 | putative lysil-tRNA synthetase LysU | Not tested | PAI III 536 | Protein | 7e-105 | 50 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| lysS | NP_222891.1 | lysyl-tRNA synthetase | VFG1668 | Protein | 4e-105 | 50 |
