Gene Information

Name : serS (jhp1373)
Accession : NP_224091.1
Strain : Helicobacter pylori J99
Genome accession: NC_000921
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1505939 - 1507186 bp
Length : 1248 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATTGATAGAAAACTTTTATTGCAAGATTTTGACAAGGTGGCTCTTTCTTTAAAAAAGCGTAACCATGCGATGGACGA
TGAATTAGAGCGTTTGCGCGAAGCCATCGCACATTATAAAAAGCAACTCATTGAATTAGAAGGCTTGCAGGCCTTTCAAA
ACAAGGTTTCTAAAGAGTTTGGTATTAAAATGGCTCAAAAAATGGATACAAGCGATCTCAAAAAAGAGCTAGAAAACAAT
AAAATCAAACTGAATGAGCTTTCCAAAAGCGTGGGCGAAGCAGAACAGGAAATGGATTTAAAGCTTTCCATAATCCCTAA
TTTAGTGGATGAAAAAACCCCTTTAGGCGCTAGCGAAGAAGACAATATAGAAATTAAAAAAATCTTAACCCCAAGAAATT
TTACTTTCAAACCCAAAGAGCATTTTGAACTCGCTCAACAAAACGGTTGGATTGATTTTGAAAGCGGCGTGAAACTCGCC
AAAAGCCGTTTTTCGGTCATTAGGGGTTTTGGGGCGAAAATTTATCGCGCGCTCATTCATTTAATGTTAGATTTTAATGA
AAAAAATGGCTTTGAAATCATTTACACGCCGGCGTTAGTGAATGAAAAAATGCTTTTTGGGACCGGGCAATTACCCAAAT
TCAAAGAAGATGTTTTCAAAATAGAAAATGAAAATTTGTATCTGATCCCCACCGCTGAAGTAACGCTCACCAATTTATAC
AACGACACCATTATTAGCGTTGAAAACCTCCCCATTAAAATGACCGCACACACGCCTTGTTTCAGGAGCGAAGCAGGGAG
CGCTGGAAAGGATACAAGGGGGATGATAAGACAGCACCAGTTTGATAAAGTAGAGCTTGTGGCTATCACGCACCCTAAAG
AAAGCGATGCGATGCAAGAGCATATGCTAGAGAGCGCGAGCGAAATTTTAAAGGCTTTGGAATTACCGCACCGGTTCGTG
CAATTGTGCAGCGGGGATTTAGGCTTTAGCGCGAGCAACACGATAGACATTGAAGTGTGGCTGCCTGGGCAAAATTGTTA
CAGAGAAATCAGCTCCGTGTCTAACACGAGGGATTTTCAGGCTAGGCGCGCCAAAATCCGCTTCAAAGAAAATCAAAAAA
ACCAATTAGTACACACCTTAAACGGCTCTTCTTTAGCGGTAGGAAGGACGATGGTCGCTTTAATGGAAAACCACCAGCAA
GCGGATGGGAGCATCCACATTCCTAAGGCGTTAGAAAAATACCTTTAA

Protein sequence :
MIDRKLLLQDFDKVALSLKKRNHAMDDELERLREAIAHYKKQLIELEGLQAFQNKVSKEFGIKMAQKMDTSDLKKELENN
KIKLNELSKSVGEAEQEMDLKLSIIPNLVDEKTPLGASEEDNIEIKKILTPRNFTFKPKEHFELAQQNGWIDFESGVKLA
KSRFSVIRGFGAKIYRALIHLMLDFNEKNGFEIIYTPALVNEKMLFGTGQLPKFKEDVFKIENENLYLIPTAEVTLTNLY
NDTIISVENLPIKMTAHTPCFRSEAGSAGKDTRGMIRQHQFDKVELVAITHPKESDAMQEHMLESASEILKALELPHRFV
QLCSGDLGFSASNTIDIEVWLPGQNCYREISSVSNTRDFQARRAKIRFKENQKNQLVHTLNGSSLAVGRTMVALMENHQQ
ADGSIHIPKALEKYL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-77 46