Gene Information

Name : nadC (jhp1273)
Accession : NP_223991.1
Strain : Helicobacter pylori J99
Genome accession: NC_000921
Putative virulence/resistance : Unknown
Product : nicotinate-nucleotide pyrophosphorylase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0157
EC number : 2.4.2.19
Position : 1393792 - 1394613 bp
Length : 822 bp
Strand : -
Note : catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide

DNA sequence :
ATGGAGATAAAAACCTTTTTAGAATGCGCCTTAAAAGAAGATTTAGGGCATGGGGATTTGTTTGAAAGGGTGTTAGAAAA
GGATTTTAAAGCCACAGCCTTTGTGAGGGCTAAACAAGAGGGCGTGTTTTCAGGCGAAAAATACGCTTTAGAGTTGCTTC
AAATGACCGGCATTGAATGCGTTCAAAACATTAAGGATAAAGAGCGTTTCAAGCCTAAAGACACCTTAATGGAGATTAGG
GGGGATTTTAGCATGCTTTTAAAGATTGAACGCACCCTATTAAATCTGTTGCAACACAGCAGCGGGATCGCCACTTTAAC
GAGCCGTTTTGTAGAAGCTTTAAATTCTCCCAAAGTGCGTTTGTTGGACACACGAAAAACCAGACCCCTTTTAAGGATCT
TTGAAAAATATTCCGTGCTTAATGGGGGGGCGAGCAACCACCGCTTAGGGCTAGATGACGCTTTAATGCTTAAAGACACG
CATTTAAAGCATGTGAAAGATCTAAAGAGCTTTTTAACGCATGCCAGAAAAAACTTGCCTTTCACGGCTAAAATTGAAAT
TGAATGTGAGAGCTTTGAAGAGGCCAAAAACGCCATGAGCGCGGGAGCGGATATTGTGATGTGCGATAACATGAGCGTTG
GGGAGACTAAAGAAATTGCCGCTTACAGAGAGGCGCATTACCCCTTTGTCTTATTGGAAGCGAGCGGGAATATCTCGCTA
GAGAGCATCAACGCTTACGCCAAAAGCGGCGTGGATGCCATTAGCGTAGGGGCTTTAATCCATCAAGCCACTTTTATTGA
CATGCACATGAAAATGGCTTAA

Protein sequence :
MEIKTFLECALKEDLGHGDLFERVLEKDFKATAFVRAKQEGVFSGEKYALELLQMTGIECVQNIKDKERFKPKDTLMEIR
GDFSMLLKIERTLLNLLQHSSGIATLTSRFVEALNSPKVRLLDTRKTRPLLRIFEKYSVLNGGASNHRLGLDDALMLKDT
HLKHVKDLKSFLTHARKNLPFTAKIEIECESFEEAKNAMSAGADIVMCDNMSVGETKEIAAYREAHYPFVLLEASGNISL
ESINAYAKSGVDAISVGALIHQATFIDMHMKMA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nadC YP_281534.1 nicotinate-nucleotide pyrophosphorylase Not tested Not named Protein 6e-30 41