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Name : metB (jhp0098) Accession : NP_222819.1 Strain : Helicobacter pylori J99 Genome accession: NC_000921 Putative virulence/resistance : Resistance Product : cystathionine gamma-synthase Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG0626 EC number : 2.5.1.48 Position : 109477 - 110619 bp Length : 1143 bp Strand : - Note : catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine and L-cysteine; or Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine DNA sequence : ATGCGCATGCAAACCAAATTAATCCATGGGGGCATTAATGAGGACGCGACAACGGGGGCGGTGAGCGTGCCTATTTATCA AACTTCCACCTACCGCCAAGACGCCATAGGTCGCCACAAAGGCTATGAATACTCTCGCTCAGGCAACCCCACACGCTTTG CTTTAGAAGAACTCATCGCCGATTTAGAAGGGGGGGTTAAGGGGTTCGCTTTCGCTTCTGGTTTAGCCGGAATCCACGCC GTTTTTTCCCTCTTGCAATCAGGCGATCATGTGTTATTGGGCGATGATGTTTATGGGGGGAATTTCCGCTTGTTTAATAA GGTGCTTGTCAAAAACGGGCTTTCTTGCACCATTATAGACACTAGCGATCTATCCCAAATTAAAAAGGCTATCAAGCCCA ACACCAAAGCCCTTTATTTAGAAACCCCTAGTAACCCCTTGCTTAAAATCACGGATTTAGCGCAATGCGCTAGTGTCGCT AAAGAACATAATTTGCTCACTATCGTGGATAACACCTTTGCCACCCCCTATTGCCAAAACCCGCTTCTTTTGGGAACGGA CATTGTGGCGCATAACGGCACAAAATACTTAGGCGGGCATAGCGATGTGGTTGCTGGGCTTGTAACCACCAATAATGAAG CGCTAGCCCAAGAGTTCGATTTTTTCCAAAACGCTATCGGTGGGGTGTTAGGCCTTCAAGACAGCTGGCTGTTGCAAAGA GGGATTAAAACGCTGGGATTGCGCATGGAGGCCCATCAAAAAAACGCCCTTTGCGTGGCTGAGTTTTTAGAAAAACACCC TAAAGTGGAAAGGGTTTATTACCCAGGCCTACCCACCCACCCTAACCACGAACTGGCCAAAGCCCAAATGCGTGGCTTTA GCGGGATGTTTTCTTTCACCCTCAAAAATGACAGCGAAGCGGTTGCTTTTGTAGAAAGCCTTAAATTATTCATTTTAGGC GAGAGTTTGGGCGGAGTGGAAAGCTTGGTAGGGATTCCAGCGCTAATGACCCATGCGTGTATCCCTAAAGCGCAACGAGA AGCCGCCGGAATCAGAGATGGTTTGGTGCGCTTGTCTGTGGGGATTGAGCATGAACAGGATCTGTTAGAAGATTTAGATC AAGCGTTCGCTAAAATAAGCTAA Protein sequence : MRMQTKLIHGGINEDATTGAVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHA VFSLLQSGDHVLLGDDVYGGNFRLFNKVLVKNGLSCTIIDTSDLSQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVA KEHNLLTIVDNTFATPYCQNPLLLGTDIVAHNGTKYLGGHSDVVAGLVTTNNEALAQEFDFFQNAIGGVLGLQDSWLLQR GIKTLGLRMEAHQKNALCVAEFLEKHPKVERVYYPGLPTHPNHELAKAQMRGFSGMFSFTLKNDSEAVAFVESLKLFILG ESLGGVESLVGIPALMTHACIPKAQREAAGIRDGLVRLSVGIEHEQDLLEDLDQAFAKIS |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAR0460 | YP_039909.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 6e-99 | 54 |
| SAS0418 | YP_042545.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 4e-100 | 54 |
| metB | YP_281510.1 | cystathionine beta-lyase | Not tested | Not named | Protein | 3e-75 | 47 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| metB | NP_222819.1 | cystathionine gamma-synthase | BAC0207 | Protein | 3e-62 | 42 |
