Gene Information

Name : TP0939 (TP0939)
Accession : NP_219375.1
Strain : Treponema pallidum Nichols
Genome accession: NC_000919
Putative virulence/resistance : Virulence
Product : pyruvate oxidoreductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG0674
EC number : -
Position : 1020376 - 1023930 bp
Length : 3555 bp
Strand : -
Note : similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity

DNA sequence :
ATGTCTGAGAAGAACCTCGTCATGATGGATGGTAACACCGCAGTGGGGCACGTTGCTCACGCGCTTAGTGAGGTCATTGC
TATCTTCCCTATCACTCCCTCCAGTCCTATGGGAGAAATCGCAGACGAATATTCCGCACGGGGGCGCACAAATATCTGGG
GTACCGTTCCCACCGTTGTAGAACTTCAGTCTGAGGCAGGCGCTTCGGGAGCTGTTCATGGCGCACTGACGACGGGGGCG
CTCTCTTCTACTTTTACTGCTTCTCAGGGATTGCTGCTTATGATCCCGAATATGTATAAGATCGCAGGGGAGCTTACGAG
CGCTGTTTTTCACGTTGCTGCACGCGCTGTCGCCACAAGTTCTCTTTCTATCTTTGGTGATCATCAAGACGTGATGGCGT
GCCGCCAGACAGGTTGGGCGCTCCTTGCTTCCAACAGTGTTCAGGAGGCCATGGACACCGCAGTTATTGCTCATGCTGCG
ACGCTCGAGGCGCGCGTGCCTTTTGTTCATTTTTTTGACGGTTTTAGGACTTCTCATGAGATTCAGAAAATTGAAGAAGT
CTCTTATGACGTCATGCGTGCTATGATCGACGACGAACTTGTCCATGCGCACCGCATGCGTGGACTGACTCCCGAAAAGC
CAGTGGTCCGCGGCACAGCACAGAATCCTGATGTGTATTTTCAGGTCCGCGAATCAGTGAATAGGTACTATGCGGTTGCG
CCCTCCATTGTCCAAAAAGCTATGGACCGCTACGCGGCGCTTACCGGACGCCAGTACCGTCTTTTCGATTACTACGGTGC
ACCCGATGCAGAGAAGGTGATTGTCATGATTGGCTCCGGCTCTGAGGCCGTTGAAGAGACAGTTGATGTGCTCAATGCTC
AGGGAGGAAAGTGTGGTCTAGTCAAGGTGCGCTTGTATCGCCCGTTCAGCGCAGAGTGTTTTGTCAATGCATTGCCCAAA
ACGGTGCAGGCGATTGCAGTGCTCGATCGAACGAAAGAGCCAGGTTCTCTGGGCGAACCTCTCTATGAGGATGTGCGCAC
CGCTATCGGCCAGATGCAGAGCCAGAAGAAGTGTCCGTTTACGCATTACCCTCTCGTGCTCGGTGGTCGCTATGGCCTGG
GTTCTAAGGAGTTTACGCCCGCGATGGCCAAAGGAGTGTTTGATAACCTCAGTGGGAAGAAGATCCCGAACTTCTCGGTC
GGTATAGAGGATGATGTTACGTTCAGCAGCGTAGACTTTGATCCGAACTTTCAGCTTGATGATCAAGATGTGTGTCAGGC
GGTGTTCTATGGTCTGGGCTCGGACGGTACAGTAGGCGCGAATAAAAATTCAATTAAGATTATTGGTGAGGCGACGGATA
ATAACGCGCAGGCTTACTTTGCCTACGATAGCAAGAAGTCTGGTGGTTTTACTATTTCTCATTTGCGTTTTGGAAAGCAG
AAGATCCGTAAGCCCTACCTCATTACGCAGGCGGATTTTGTAGCGTGTCATAAGTTTACGTACCTTGAAACCTTTGACAT
GCTCAAAACGCTCAAGCGTGGAGGGACCTTTTTGCTGAATGCGCCGTACAGTGAGCATGAGGTGTGGCATCACATACCCA
TAGAAGTCCAGCGTCAGATCATTGAAAAGGAGGTGAAGTTTTACGTCATCGATGCGATTTCTATCGCTCAGAAGGCGGGG
ATGGGCACACGTATCAATGTGGTGATGCAAACGGCTTTTTTCAAAATTTTTGGTATCTTGCCGGAAGCTGAGGCGATTGA
CCTGATTAAGAAATTTATACAGAAGGCCTACGGCAAAAAGGGTGGGGAGGTTGTACAGAGGAACATCACCACTATCGATA
TGGCGCTCGCTGGGGTGGGATTGGTGGAGTATCCGGGAGTTGCCGGTAGTTTGGTGACGCGTCGTCCTGCGATGAGTTCC
GATGCTCCGGAGTTTGTGCAAAGCGTGTTAGGTACTATTGCGCTCAATCAGGGGGATAGTCTTGGGGTGAGCGCACTACC
AGAGGATGGTACCTATCCTACTGGTACCACGCAGTACGAGAAGCGCTGTATAGCCGAGACTATACCCATTTGGGATCCGT
CTGTTTGTATCCAGTGTGGTCAGTGCGCTATGGTGTGTCCTCACGCAGTTATCCGCATGAAAGCGTACGATGGTAAGGAG
CTCGAGCATGCGCCTTCTAAGTTTGCTTCCTGTGACTACAAAGGCAAGGAATTTGGGGAGGCGAAGTTTACGATTCAGGT
TTCCCCAGAGGACTGCACAGGTTGTGGCCTGTGCGTGCAGCAATGTCCGGCAAAAAATAAGGCTGATCCTACGCGTAAGG
CTATCAACATGGAAAGTTTTTCCAAGCACCGTGCGGTGGAGTCTGAGAACTGGGCCTTCTTTGTTAAACTGCCCGATCCT
GAGGCGAAGAAGCTCAATTTGAGTCTGCCAAAAGGGGCGTCCATGAAAAGACCTCTTTTTGAGTTCTCTGGTGCCTGCCC
AGGCTGCGGGGAGACCCCCTACATCCGCTTGATGACGCAGATTGTTGGGGATCGCGCCATTATCGCGAATGCAACCGGAT
GTTCTTCGATATATGGGGGAAATTTGCCTACAACCCCCTATACGACGCGTCCTGATGGTCGCGGCCCCGCTTGGTCAAAT
TCTCTTTTCGAAGACGCAGCAGAGTTTGGCTTCGGAATGCGCGTGACTAGTGACAAACTTGCAGAGTATGCCCGCGAGGT
TGGACGCAAGTTGCAGGAAAAAGGGGTGGCGGCTGATCTGTTTGCGAGTATTTTTTCTAACCAGCAGGCGGACGATGTTG
CAGTGGAAGAGCAGCGTGCCTACGTTAATCAGCTTAAGAAAGTGCTCAGTGAGAGTACTGAACCCCTTGCAAAGGAAATG
CTTTCTCTCGTTGACCACCTTATCAAACGCTCGGTGTGGATTTTTGGGGGAGACGGCTGGGCCTATGATATTGGCTACGG
TGGTCTAGATCACGTGTTGGCCTCTGGGCGCAATATTACCGTCCTTGTTATGGATACGGAGGTGTATTCCAACACCGGTG
GTCAGATGTCGAAGGCCACGCCTATCGGGGCCGTCGCAAAGTTTGCCGCGGCGGGGAAGGAGATCAGTAAAAAGGATATT
GGTTTGATGGCCATGAGCTATGGGTATGTGTACGTGGCACGTGTCGCGATGGGAGCGAACATGAGTCAAGTGGTCAAGGC
GTTTAGAGAGGCTGAAAGTTATGATGGTCCATCGCTTATTGTCGCCTACAGCCACTGTATTAGCCACGGGATTGATATGT
CCAAGGGCATGATTAATCAGAAAGAGGCCGTCGCGTGTGGTTTGTGGCCGTTGTACCGCTACGATCCCCGTCGCATTGCG
GAAGGAAAAAATCCATTTCAGCTTGACAGTAAGGAACCTGATTTTAAGCTTGCGGATTTCATGTACAAAGAAGTTCGGTT
CAAGACGCTTAAGAATGCAAATCCCGAGCGAGCTGAAATGCTGCTCAAGCGCGCAGAAGAGAAGGCGCGGAGACAGTGGC
AAGAGTACAAGTACCTTGCGGACCGTCCGTTCTAG

Protein sequence :
MSEKNLVMMDGNTAVGHVAHALSEVIAIFPITPSSPMGEIADEYSARGRTNIWGTVPTVVELQSEAGASGAVHGALTTGA
LSSTFTASQGLLLMIPNMYKIAGELTSAVFHVAARAVATSSLSIFGDHQDVMACRQTGWALLASNSVQEAMDTAVIAHAA
TLEARVPFVHFFDGFRTSHEIQKIEEVSYDVMRAMIDDELVHAHRMRGLTPEKPVVRGTAQNPDVYFQVRESVNRYYAVA
PSIVQKAMDRYAALTGRQYRLFDYYGAPDAEKVIVMIGSGSEAVEETVDVLNAQGGKCGLVKVRLYRPFSAECFVNALPK
TVQAIAVLDRTKEPGSLGEPLYEDVRTAIGQMQSQKKCPFTHYPLVLGGRYGLGSKEFTPAMAKGVFDNLSGKKIPNFSV
GIEDDVTFSSVDFDPNFQLDDQDVCQAVFYGLGSDGTVGANKNSIKIIGEATDNNAQAYFAYDSKKSGGFTISHLRFGKQ
KIRKPYLITQADFVACHKFTYLETFDMLKTLKRGGTFLLNAPYSEHEVWHHIPIEVQRQIIEKEVKFYVIDAISIAQKAG
MGTRINVVMQTAFFKIFGILPEAEAIDLIKKFIQKAYGKKGGEVVQRNITTIDMALAGVGLVEYPGVAGSLVTRRPAMSS
DAPEFVQSVLGTIALNQGDSLGVSALPEDGTYPTGTTQYEKRCIAETIPIWDPSVCIQCGQCAMVCPHAVIRMKAYDGKE
LEHAPSKFASCDYKGKEFGEAKFTIQVSPEDCTGCGLCVQQCPAKNKADPTRKAINMESFSKHRAVESENWAFFVKLPDP
EAKKLNLSLPKGASMKRPLFEFSGACPGCGETPYIRLMTQIVGDRAIIANATGCSSIYGGNLPTTPYTTRPDGRGPAWSN
SLFEDAAEFGFGMRVTSDKLAEYAREVGRKLQEKGVAADLFASIFSNQQADDVAVEEQRAYVNQLKKVLSESTEPLAKEM
LSLVDHLIKRSVWIFGGDGWAYDIGYGGLDHVLASGRNITVLVMDTEVYSNTGGQMSKATPIGAVAKFAAAGKEISKKDI
GLMAMSYGYVYVARVAMGANMSQVVKAFREAESYDGPSLIVAYSHCISHGIDMSKGMINQKEAVACGLWPLYRYDPRRIA
EGKNPFQLDSKEPDFKLADFMYKEVRFKTLKNANPERAEMLLKRAEEKARRQWQEYKYLADRPF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AFJ97267.1 pyruvate ferredoxin Virulence Not named Protein 0.0 48