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Name : TP0071 (TP0071) Accession : NP_218511.1 Strain : Treponema pallidum Nichols Genome accession: NC_000919 Putative virulence/resistance : Virulence Product : ATP-dependent Clp protease subunit B (clpB) Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : - Position : 75906 - 78542 bp Length : 2637 bp Strand : - Note : similar to PID:1163118 SP:P53532 percent identity: 59.57; identified by sequence similarity DNA sequence : ATGAACACAGACAGGTACACAGTCAAAGCAAGCGAAGCGCTCAATGACGCCATATCTCTGGCAGAAGCGGAGAACCACGG TCAAGTTGAGGAGGAACATCTACTCCACGCCCTACTTTCCCAGAAAGACGGGATTATCTCTCCGCTCATTGAAAAAATTG GGGCAAAACCGGACTTCCTGTACGATGAATTACTCCAATGCCTGCGCCGCAAACCACGTGTTACCGGTCCTGCCGCCCAA ACGCGCTGTGCACCAACGCTGAGCAAAGCCTGTGCACGTGCAGAACGCCTCGCGCTCAAGAACCAAGATGAATATGTCTC CTGCGAACATCTCCTGCTTGCCATAAGTGAGACAGATAGCAACACTGCACGTCTCCTTCACAGTCAGGGCATTACCAGTA AAACTATCAGTGCCGCCCTCAAAGATATACGCGGCAGCAAGCGCGTTACGAGCCAGGATCCAGAATCAACATTCCAGTGC TTGGAGAAATACTGCCGAGATCTTACTACCCTCGCCCGAGAAGAAAAAATAGATCCGGTTATTGGACGTGATGAAGAGAT CCGGCGCGTTATGCAGGTACTCTCACGTCGTACAAAAAATAACCCAGTGCTTATTGGAGAACCCGGCGTAGGGAAAACCG CTATTGTCGAGGGACTTGCACGCCGTATCGTTTCAGGAGACGTACCAGAAAGCCTCAAGGGAAAGCGTTTGCTTTCCCTT GACCTCGGCGCATTGGTTGCCGGTGCAAAGTTCCGCGGGGAATTTGAAGAACGACTAAAAGCGGTAATTGAAGCGGTACA GAAAAGCGACGGTGGCGTTATTTTATTCATTGATGAACTACACACGCTCGTAGGCGCCGGCGCAAGTGAGGGATCTATGG ATGCGTCGAACCTTCTGAAACCTGCGCTTGCGCGCGGTGAATTGCGTTCAATCGGCGCAACCACGCTCAACGAATATCGC AAATATATCGAAAAGGACGCAGCGCTCGAACGCCGCTTTCAGCAAGTGTACTGCGTACAGCCTACGGTGGAGGACACCAT TGCTATCCTGCGCGGTTTGCAAGAAAAGTACGAAGTGCATCACGGGGTACGTATCAAAGATGAAGCGCTTGTTGCAGCAA CCGTTTTGTCTGACCGTTACATCACCAACCGCTTTTTACCAGATAAGGCGATTGATCTGGTGGATGAAGCAGCAAGCCGC CTGAAAATGGAAATTGAAAGTCAGCCTGTTGAGCTAGACCAGGTGGAGCGCAAGATATTACAGCTGAATATCGAAAAGGC CTCTCTCCTTAAAGAAAGTGATCCGGCTTCAAAGGAACGTTTGGAAAAGTTAGAAAAAGAGCTCGCAGGCTTCCTAGAGC GCCGTGCTGCAATGCAGGTCCAATGGCAAAATGAGAAAGGGAGGATAGAAGAGTCACGCCGCTACAAAGAGGAGCTTGAG CGTCTCCGCATTGAGGAAACCATGTTTTCACGTGAAGGGGACCTGAACAAGGCTGCAGAACTTCGGTATGGCAAAATTCC AGAACTTGAAAAAAAAATCATGCTTCTTACTGCAGAAGTAGAGAAAAAATCCGGTCTAGAAGGACAGCTCTTGCGCGAGG AAGTGTGTGAAGAGGACATTGCGAAAATTATTTCTATGTGGACCGGAATTCCGGTATCCAAAATGATGGCAAGCGAGCAA CAGAAATATCTGCAGCTTGAGTCAGTACTCATGCAACGTGTGGTAGGGCAGGACGAAGCAGTGCGGGTAATTTCCGACGC GATTCGTCGTAATAAGGCAGGACTTTCTGATACGCGCCGTCCTCTTGGCAGTTTCTTATGTGTCGGTCCCACGGGGGTAG GAAAGACAGAACTTGCACGTACGTTAGCTGATTTTCTTTTCAACGATGAGCGTGCACTGACGCGTATCGATATGAGTGAA TACATGGAAAAACACGCGATCAGCCGACTCATTGGCGCGCCCCCGGGGTATGTGGGCTATGACGAGGGGGGACAATTGAC AGAAGCGGTACGACGTAGACCCTACAGCGTACTTCTTTTTGATGAAGTAGAGAAAGCGCACCAGGATGTGTTTAATATAT TCCTGCAAATACTCGACGATGGGCGCTTGACTGACGGCCAAGGAAGGGTGGTGGATTTCCGCAACACGATCATCATCATG ACCAGCAATATCGGATCAGAGCATATTCTTTCTGCACGCGAGTCGCGCACACACACGTCGGACTTGCCTGTACCCGAGAC ACAATCTACAGAAGAACAAACTCTACCAGAGCAGATACGGGGATTACTGCACACATACTTTCGCCCAGAATTCTTAAACC GGATTGACGAAGTGTTAATTTTTAAGCGTCTCACACGGAAACATATTCGCCTCATCACAGACATCCAACTGCAGATGGTA GTGGAGCGTTTGGAAAGTCGACATATAAAACTTCGTGTGCGTGACGCGGCGAAAGCCTATCTTGCGGAGCGCGGATACGA CGACACTTTCGGAGCACGACCACTGAAGCGTGCAATCCAAACGGAATTGGAAAATGCCCTAGCGCGTGAGATTCTCAGTG GCCGATTCAGAGGCGGCTCAACTATCGTGGTGGATATGTGTAAAGATGCTCTGTGTTTCACTGAACAAACATCCTGA Protein sequence : MNTDRYTVKASEALNDAISLAEAENHGQVEEEHLLHALLSQKDGIISPLIEKIGAKPDFLYDELLQCLRRKPRVTGPAAQ TRCAPTLSKACARAERLALKNQDEYVSCEHLLLAISETDSNTARLLHSQGITSKTISAALKDIRGSKRVTSQDPESTFQC LEKYCRDLTTLAREEKIDPVIGRDEEIRRVMQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVSGDVPESLKGKRLLSL DLGALVAGAKFRGEFEERLKAVIEAVQKSDGGVILFIDELHTLVGAGASEGSMDASNLLKPALARGELRSIGATTLNEYR KYIEKDAALERRFQQVYCVQPTVEDTIAILRGLQEKYEVHHGVRIKDEALVAATVLSDRYITNRFLPDKAIDLVDEAASR LKMEIESQPVELDQVERKILQLNIEKASLLKESDPASKERLEKLEKELAGFLERRAAMQVQWQNEKGRIEESRRYKEELE RLRIEETMFSREGDLNKAAELRYGKIPELEKKIMLLTAEVEKKSGLEGQLLREEVCEEDIAKIISMWTGIPVSKMMASEQ QKYLQLESVLMQRVVGQDEAVRVISDAIRRNKAGLSDTRRPLGSFLCVGPTGVGKTELARTLADFLFNDERALTRIDMSE YMEKHAISRLIGAPPGYVGYDEGGQLTEAVRRRPYSVLLFDEVEKAHQDVFNIFLQILDDGRLTDGQGRVVDFRNTIIIM TSNIGSEHILSARESRTHTSDLPVPETQSTEEQTLPEQIRGLLHTYFRPEFLNRIDEVLIFKRLTRKHIRLITDIQLQMV VERLESRHIKLRVRDAAKAYLAERGYDDTFGARPLKRAIQTELENALAREILSGRFRGGSTIVVDMCKDALCFTEQTS |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| STY0294 | NP_454876.1 | ClpB-like protein | Not tested | SPI-6 | Protein | 4e-106 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| TP0071 | NP_218511.1 | ATP-dependent Clp protease subunit B (clpB) | VFG2084 | Protein | 8e-103 | 43 |
| TP0071 | NP_218511.1 | ATP-dependent Clp protease subunit B (clpB) | VFG2076 | Protein | 7e-112 | 41 |
