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Name : TP0549 (TP0549) Accession : NP_218988.1 Strain : Treponema pallidum Nichols Genome accession: NC_000919 Putative virulence/resistance : Virulence Product : ATPase (clpC) Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : - Position : 593081 - 595525 bp Length : 2445 bp Strand : + Note : similar to GB:D26185 SP:P37571 GB:U02604 GB:X75930 PID:442360 percent identity: 44.35; identified by sequence similarity DNA sequence : GTGTTACAGGACCTATCCGCAAATGCCCGTAAGGTACTGCTCGAGCTCGGTCAGACCGTTGCGCGTGAGGCTCGCGCCTC GCTCCTTCAGCCAGAGCACATTCTGCTCGCCCTCATTCAGCACAAAGTAGGCCGCGGCTACAAGCTCATCGAAAAACTCA TTGAAGATGTCGCTACCGTCCGCCTCATCCTCGAGCAACACGTCCTTACCAATGAGGGAGACGTCGCCAGTCCCCAGGAC CTGCCCGTCTCAGGACGCGTCAAACACTTGCTCGACATCGCAGCAATGGAAGCACGCTCCCTGCGGTGCGCTTACATCGG TACCGAACACCTCGTTATCGCCTTTGCCCGAGAGGAGCAAAATCCTCTCTTCCAAAGCCTCATCCGAGAAGGACTCTCGC TCGATGACCTGCGAAACGCGAGCATTATATCCTCACCTCATTCTGATACCACCCGCACCCGGCTCGAGCGGAAAGTTGCA AGTGTCCTTGACGAATACGGCACCGACCTTACCGAACGCGCGCGCGCCGGCGCCCTCAATCCGGTCATCGGACGAAACAA AGAAATTACCCGCGTCATTCAAATCCTGTGCCGGAGAGGAAAAAATAACCCGGTGCTCATCGGAGAGCCAGGTGTCGGGA AAACTTCCATCGTTGAGGGGCTCGCGTACGCCATCGTTCGGGAGGAGGTCCCGCACATCCTGCTGCACACCCGCGTCGTT TCCCTAGACCTTGCCGCCGTCATAGCAGGAACAAAGTACCGCGGCCAGTTTGAGGAGCGGCTCAAACGCATTATTAAGGA GGTGGAAGAAACTGAAAAAGTCATCCTTTTCATCGATGAGCTGCACACACTCATCGGAGCAGGAGGCACGCAGGGGTCTT TGGACGCCGCCAACATGCTCAAGCCGGCCCTTGCACGCGGACAAATCCAGTGCATTGGGGCAACAACCCTGGCAGAGTAT CGCCGTTACTTTGAAAAAGACGCAGCTCTCACCCGCCGATTCCGATCGGTGCTCGTGCGTGAACCGAGCTTTGAAGAAAC CTGCACTATTTTACGCAAAATAAAATCACACTACGAACGACATCACCAGGTGATATACCAAAGCGATGCGCTTGAAAAAA TTGTTGAGCTTTCACGGCGCTACATCCCTGAGCGGTTCTTTCCAGATAAGGCAATTGATCTTATGGATGAAGTAGGAGCC ATGAAACGGGTACAACAGCGCGCGGATACGCAGGTATTGCGTTCCTTTTCCATAAAAGTTGCTAATCTTACCACAGAGAC TGAGCGCGCCATTGCGCTTGAAGATTGGGCGCGCGCGCGTTCCTTACACACCGATGTGGTGCAGCTGCGCAGACGGCTCC ACGCGCTGAAGGTAGAGTGGAGCGCGCGCGAAGCGCTGTCTATCTTTGCAGAAGATGTTGCACAGGCTGTCTCTCTCATG ACCGATATCCCGGTACATTCGCTCGAAGGGGATGAGCTGTGCCGCTTTACCAATATCGAACGGGATCTTTGTGCCACCGT GCGTGGGCAGCGCGAGGCCATTGCAACGCTCGCGCGCGCTATCGTACGCGCGCGTGTCGGCATCTCTTCAGACACGCGCC CCATTGGCTCCTTCCTGTTTCTTGGACCGACCGGTGTAGGCAAAACGCTCTTGGCAAAGACACTCGCGGAATTTCTTTTC GGTTCAGCAGACGCGCTCATCCGCATTGACATGAGCGACTACATGGAACGCTACAACACCTCACGCCTCATGGGAGCACC GCCTGGATACGTGGGATTTGAAAATGGCGGTCTACTTACCGAGCGCGTACGGCACCGCCCTTTTTCTGTCATCCTTCTGG ATGAAATTGAAAAGGCGCATCCAGATGTCTTCAATGTTCTCCTCCAGGTGTTAGAAGAAGGAGAGCTGCAAGACAACCTG GGGCACACGGTGAACTTCCGCAACACTATCATCATCATGACCAGCAATGCAGGCACACGCGGCCTGGGGGAAAACGTTCC TGGCTTTCAAACCGCACGCGCGCGAAACATCGAGTACCGTCAGCTGCGCGTACAGGCCCTCCGGGAAATAAAACGCATCT TCTCTCCGGAGTTTCTCAATCGCGTTGACGAGTGCGTAGTGTTTGCTCCGCTTGAGCGAGAGACCCTGCAGGAAATTTTA GAATGCGAACTGAAGAAGCTCGCAGAACGCCTACGCGGTAAAGATATTGTGCTGCGCTACAGCGCGGCTGCAAAGGCCTA CTGTCTTGAACACGGCTTTGACCCATTCTTGGGCGCACGCCCCCTGCGCCGCGTATTGCAGCAAGAAATTGAAAATGAGC TTGCGCTGCGCATGATTCACGGAACGTTGCGCGCAGGATCGTGCGTGCACATAGACTCAGACGGCGCGCGCCTCCACCTT TCTACCGAAAAAAGTTACCTGACGCTGCATCCCCAAGAAATATAA Protein sequence : MLQDLSANARKVLLELGQTVAREARASLLQPEHILLALIQHKVGRGYKLIEKLIEDVATVRLILEQHVLTNEGDVASPQD LPVSGRVKHLLDIAAMEARSLRCAYIGTEHLVIAFAREEQNPLFQSLIREGLSLDDLRNASIISSPHSDTTRTRLERKVA SVLDEYGTDLTERARAGALNPVIGRNKEITRVIQILCRRGKNNPVLIGEPGVGKTSIVEGLAYAIVREEVPHILLHTRVV SLDLAAVIAGTKYRGQFEERLKRIIKEVEETEKVILFIDELHTLIGAGGTQGSLDAANMLKPALARGQIQCIGATTLAEY RRYFEKDAALTRRFRSVLVREPSFEETCTILRKIKSHYERHHQVIYQSDALEKIVELSRRYIPERFFPDKAIDLMDEVGA MKRVQQRADTQVLRSFSIKVANLTTETERAIALEDWARARSLHTDVVQLRRRLHALKVEWSAREALSIFAEDVAQAVSLM TDIPVHSLEGDELCRFTNIERDLCATVRGQREAIATLARAIVRARVGISSDTRPIGSFLFLGPTGVGKTLLAKTLAEFLF GSADALIRIDMSDYMERYNTSRLMGAPPGYVGFENGGLLTERVRHRPFSVILLDEIEKAHPDVFNVLLQVLEEGELQDNL GHTVNFRNTIIIMTSNAGTRGLGENVPGFQTARARNIEYRQLRVQALREIKRIFSPEFLNRVDECVVFAPLERETLQEIL ECELKKLAERLRGKDIVLRYSAAAKAYCLEHGFDPFLGARPLRRVLQQEIENELALRMIHGTLRAGSCVHIDSDGARLHL STEKSYLTLHPQEI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| clpC | YP_005163377.1 | ATP-dependent Clp protease ATP-binding subunit | Not tested | Not named | Protein | 2e-148 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| TP0549 | NP_218988.1 | ATPase (clpC) | VFG0080 | Protein | 1e-133 | 50 |
| TP0549 | NP_218988.1 | ATPase (clpC) | VFG0079 | Protein | 4e-163 | 44 |
