Gene Information

Name : TP0164 (TP0164)
Accession : NP_218603.1
Strain : Treponema pallidum Nichols
Genome accession: NC_000919
Putative virulence/resistance : Virulence
Product : ABC transporter, ATP-binding protein (troB)
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1121
EC number : -
Position : 185685 - 186485 bp
Length : 801 bp
Strand : +
Note : similar to GP:1777934 percent identity: 100.00; identified by sequence similarity

DNA sequence : 
ATGGCAGAGATATCAGCAACAGCTTATGCTGTCCAGGTTGACGACCTGACGCTTGCGTATCGGCAGAAGCCGGTGCTTTG
GGACGTGGATGTGCGTATTCCAGAGGGGGTTATCGAGGCCATTATCGGTCCTAATGGGGCGGGCAAGTCGACCCTATTGA
AGGCGATCATGGGTCTTCTGCCTCTCGCTTCCGGAGAGGTGCGTGTCTTTGGGCGTCCTTTTTCAAAAGAGCGGCGACGT
GTTGCGTATGTCCCGCAGCGCAGTGCAGTGGATTGGGATTTCCCTACTACCGTTTTTGATGTGGTGCTCATGGGTTCGTA
CGGTTCGCTCGGTTGGATTCTTCGTCCGGGAAAAAGAGAAAAGGCGCGTGCCCGGGAAGCGATCGAGGAAGTAGGAATGG
GCGCCTTTTTAGACCGACAAATCAGTGAGCTTTCAGGCGGTCAGCAGCAGCGCGTGTTTCTCGCGCGGGCCTTGGTGCAG
GACGCGGATCTTTACTTCATGGATGAGCCATTTCAAGGTGTGGATGCAGCTACTGAACAAGCAATCGTTACTCTTTTAAA
AACGCTGAAAGGGCGTGGGAAAACGTTGCTTGTTGTGCATCATGATTTGCAGACGGTGGCAGAGTATTTTGACCGCGTGC
TGCTTTTAAATGTTCGCGTCATCGCTGAAGGGGCCGTCGTGTCTGCCTTCACCGAAGAATACGTTCAAAGAGCCTATGGC
GGACGGATTAGTTCCACCCTTTTTCCGAGAGGAAATAAGGAGGATGTGCACGATGCACGCGCTCATGCGTCTGTTCTCTG
A

Protein sequence : 
MAEISATAYAVQVDDLTLAYRQKPVLWDVDVRIPEGVIEAIIGPNGAGKSTLLKAIMGLLPLASGEVRVFGRPFSKERRR
VAYVPQRSAVDWDFPTTVFDVVLMGSYGSLGWILRPGKREKARAREAIEEVGMGAFLDRQISELSGGQQQRVFLARALVQ
DADLYFMDEPFQGVDAATEQAIVTLLKTLKGRGKTLLVVHHDLQTVAEYFDRVLLLNVRVIAEGAVVSAFTEEYVQRAYG
GRISSTLFPRGNKEDVHDARAHASVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ef0093 AAM75296.1 EF0093 Not tested Not named Protein 9e-38 46
EF0575 NP_814340.1 cationic ABC transporter ATP-binding protein Not tested Not named Protein 1e-37 46
sitB NP_457256.1 Iron transport protein, ATP-binding component Virulence SPI-1 Protein 2e-39 41
sitB NP_806465.1 iron ABC transporter ATP-binding protein Virulence SPI-1 Protein 2e-39 41
sitB NP_461783.1 ATP-binding protein Virulence SPI-1 Protein 1e-40 41
sitB YP_217782.1 iron transporter: fur regulated Virulence SPI-1 Protein 1e-40 41
sitB AAD41066.1 SitB Virulence centisome 63 pathogenicity island Protein 9e-41 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TP0164 NP_218603.1 ABC transporter, ATP-binding protein (troB) BAC0400 Protein 1e-106 100
TP0164 NP_218603.1 ABC transporter, ATP-binding protein (troB) BAC0440 Protein 5e-38 42
TP0164 NP_218603.1 ABC transporter, ATP-binding protein (troB) BAC0350 Protein 6e-41 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TP0164 NP_218603.1 ABC transporter, ATP-binding protein (troB) VFG0526 Protein 5e-41 41