Gene Information

Name : clpC (aq_1296)
Accession : NP_213889.1
Strain : Aquifex aeolicus VF5
Genome accession: NC_000918
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 918003 - 920435 bp
Length : 2433 bp
Strand : +
Note : -

DNA sequence :
ATGTTTGAGAAGTTCACAGAAAGGGCAAGACAAGTTATCTTGAGGGCGAGGGAAGAAGCCCTCGAGCTGGGACACAGCTA
CTTGGGAAGTGAACATATTTTGCTTGCTCTGATAAAGGATGAGGACATACCCGTCCTCGTCCTCAGCAAGCTGGGTGTCT
CTCCTGAGAAGATAAGAAAGGCCATAATGGGCCAAATAACTAAGGGAAGCCACTCGGGAGAGGTACTCTTCGCACCCGAC
GCAAAAAGGGTAATAGAGTTTGCAGTTGAAGAAGCGAGAATTCTTCACCACCAGTTCGTAGGTCCCGAACACCTACTTAT
CGGAGTGGTTAGAGAAAAGACGGGACTCGGTGGAAGAATTTTAAGGAGCTTTGGACTGGACGAGTACTCCGTAAGGAGAG
AGGTACTTCAACTACTCGGAGAACTTCCCCCTCAAGAAAGCCAGAGGTACGTATCCACTCCTAACCTTGACAGGTTCTCA
AGGGACCTCACCCAAATGGCAAGGGAAGGAAAGCTCGACCCAGTAATAGGCAGGGAAAAGGAAATAGAGAGAGTTATCCA
GATACTCGTAAGAAGAAGGAAGAACAACCCTGTCTTGCTCGGAGACCCCGGAGTTGGTAAGACGGCGATAGTAGAAGGGC
TGGCTCAAAGGATAGCAAATAAGGAAGTTCCCGAACCGCTACTCAATAAGAGGGTAGTGGCTTTAGACCTTGCGGCACTA
GTTGCGGGAACCAAGTACAGAGGACAGTTCGAAGAAAGGCTTAAGAACATCTTAAAAGAACTTGAGAAGGCTAACAACGT
AATACTCTTCATAGACGAACTTCACACACTCGTTGGAGCGGGTTCTGCGGAAGGCTCGATAGACGCATCCAATATGCTAA
AACCCGCCCTCGCGAGAGGTGAAATTCAGGTAATAGGAGCTACCACCGTAGACGAGTACAGGAAGTACATAGAAAAGGAC
GGAGCACTGGAGAGAAGGTTCCAGCCCGTTTACGTAGAACAGCCATCACCCGAGGATACGATCCAGATACTTTACGGACT
CAAACCCAAGTTTGAAGAGTTCCACAAGGTAGAGTACACACCCGAGGCAATAGAAAAGGCTGTGGAACTCTCCGTCAAGT
ACATAACCGACAGAAACCTGCCAGATAAGGCTATAGACGTTATGGACGAGGCGGGAGCACTCGTAAAGCTGAAGGCAACT
CAACTCCCTCCTGAACTCAAGGAGATAGAGGAAAAGATTAAGGAACTCGAGAAGGAAAAGGAAAAGGCTGTAAAGGAACA
GGACTACGAGAAGGCTGCAAAGATAAGGGACGAAGAGTTGAGACTCAGGGCTAAGTTCGAAACGATGAAGGCTAAGTGGA
AGGAAGAAATGGAAAAGAACAGACCCAAAGTTACGGACGAGGACGTTGCAGAAGTAGTCGCAAGGTGGACGGGCGTTCCC
GTGAAGAGGGTACACGAAAGTGATGCGGAGAAACTCCTCCACATAGAAGAAGAATTGAAGAAGAGGGTTGTAGGTCAGGA
CGAGGCTATAAAGGCAGTAGCGAAGGCGATAAGACGTTCAAGAGTCGGACTGAAAGGAAAACACAGACCCATAGGCGTAT
TCATGTTCCTAGGACCTACTGGTGTGGGTAAGACCGAAACCGCGAAGGCACTTGCGGAATACCTATTCGGAACGGAAGAC
GCACTCATCAGGTTTGATATGTCCGAGTACATGGAAAAGCACACCGTTTCAAGACTAATCGGTGCACCTCCCGGATACGT
TGGATACGAAGAAGGTGGACAGCTCACAGAGGCGGTAAGGAGAAGACCTTACAGCGTTCTCCTATTTGACGAAATAGAGA
AGGCCCACCCAGACGTATTCAACATCTTCCTCCAGATATTCGACGACGGAAGACTAACGGACGGACTCGGAAGGACCGTT
GACTTCTCCAACACCATAATAATCATGACCTCAAACCTCGGAGCTAGACTCATCACAGGCGGAACGATGGGATTCGAAAA
GAAACAGGGACTCCTTAACTTCGAAGAGATGAGGAAAAACGTCCTTGATCAGGTAAAGAGAACCTTCAGCCCTGAATTCC
TAAACAGACTGGACGAAATTATAGTGTTCAGGCCTCTCGAGAAGAAAGACATAGAACAGATACTCGAACTACAACTAAAA
GAGATAAACGAAAAACTAAAAGACTGGAACGTGAGAGTAAAACTCCACAAGTCCTTCGTAAACTGGATCATAGAAAAAGA
GTACAAGCCCGAATTCGGAGCAAGGAGCTTGAAGAGGGCTCTCCAAAGACACGTTGAAGATCTGCTCGCTGAAGAACTCA
TAAAGGGAACGCTCAAAGGCGTAGAAGAAGTAGAAATAAGGGTAAGGAACGACAAGCCCTACCTCAAACCCGTAAAGAAG
AAGGAAAAAGTAGAAGCCCTTCTCGAAAAGTAA

Protein sequence :
MFEKFTERARQVILRAREEALELGHSYLGSEHILLALIKDEDIPVLVLSKLGVSPEKIRKAIMGQITKGSHSGEVLFAPD
AKRVIEFAVEEARILHHQFVGPEHLLIGVVREKTGLGGRILRSFGLDEYSVRREVLQLLGELPPQESQRYVSTPNLDRFS
RDLTQMAREGKLDPVIGREKEIERVIQILVRRRKNNPVLLGDPGVGKTAIVEGLAQRIANKEVPEPLLNKRVVALDLAAL
VAGTKYRGQFEERLKNILKELEKANNVILFIDELHTLVGAGSAEGSIDASNMLKPALARGEIQVIGATTVDEYRKYIEKD
GALERRFQPVYVEQPSPEDTIQILYGLKPKFEEFHKVEYTPEAIEKAVELSVKYITDRNLPDKAIDVMDEAGALVKLKAT
QLPPELKEIEEKIKELEKEKEKAVKEQDYEKAAKIRDEELRLRAKFETMKAKWKEEMEKNRPKVTDEDVAEVVARWTGVP
VKRVHESDAEKLLHIEEELKKRVVGQDEAIKAVAKAIRRSRVGLKGKHRPIGVFMFLGPTGVGKTETAKALAEYLFGTED
ALIRFDMSEYMEKHTVSRLIGAPPGYVGYEEGGQLTEAVRRRPYSVLLFDEIEKAHPDVFNIFLQIFDDGRLTDGLGRTV
DFSNTIIIMTSNLGARLITGGTMGFEKKQGLLNFEEMRKNVLDQVKRTFSPEFLNRLDEIIVFRPLEKKDIEQILELQLK
EINEKLKDWNVRVKLHKSFVNWIIEKEYKPEFGARSLKRALQRHVEDLLAEELIKGTLKGVEEVEIRVRNDKPYLKPVKK
KEKVEALLEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 5e-177 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC NP_213889.1 ATP-dependent Clp protease VFG0080 Protein 9e-157 56
clpC NP_213889.1 ATP-dependent Clp protease VFG0079 Protein 0.0 55