Gene Information

Name : thiC (aq_1204)
Accession : NP_213823.1
Strain : Aquifex aeolicus VF5
Genome accession: NC_000918
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 846533 - 847906 bp
Length : 1374 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGCTAAGAGCTGAGTGGGTAGAGAAGAGGAAGAGGTTCAAAAATAAAACACAGATGCACTTAGCCCGTCAGGGAATAAT
CACCGAAGAAATGGAATACGTCGCAAAGAGAGAAGGACTTCACCCTGAATTCGTAAGGCAGGAAGTCGCAAGGGGAAGGA
TGATAATCCCTGCAAACATAAATCACCTTCACCTTGAACCTATGTGTATAGGTATAAACTCTAAAGTTAAGGTAAACGCA
AACATAGGAAATTCCGGACTTGCTTCGGACATACCCACGGAAGTTGAAAAGGCAAAAGTTGCTATAAAGTACGGTGCAGA
CACGATAATGGACCTCTCCACGGGAGAAGCTATAAAGGAAACGAGGGAAGCCATAATAAACGTCAGCACCGTTCCAGTGG
GAACAGTTCCCATATACGAGGCTTGGAAGATAGCAAAGGGAAACGTAAAGGAACTCACCGTTGACCTCATACTGGACGTA
ATAGAGGAACAGGCAAGACAGGGTGTTTCTTACATGACAATACACGCGGGTATTTTGAGGGAACACCTCCCTCTTGTTCA
GCACAGAGTTATGGGAATAGTCTCAAGGGGAGGAGCTATCTTAGCCCAGTGGATGGCAGAGCACGGCAAACAAAACCCCT
TATACGAGCACTTTGACAAGATATGTGAAATATTTAAGAAGTACGACGTCTCCTTCTCCTTGGGAGACGCACTGAGACCC
GGTTGTATAGAAGACGCAACGGACGACGCACAACTCGCAGAGCTAAAGGTTCTCGGTGAGCTCGTAGAAAAGGCCTGGAA
GCACGACGTCCAGGCTATGGTGGAAGGACCCGGACACGTCCCCCTTCATCAGGTAGAGTTCAACATGAAGATACAGCAGG
AGTGGTGTCACGAAGCCCCCTTCTACGTACTTGGACCATTAGTTCTCGACGTAGCACCCGGATACGACCACATAGGTAGT
GCTATAGGCGGAGCACTTGCAGGATGGGCAGGAGCTGCAATGCTCTGTTACATAACTCCTAAGGAACACCTCGGGCTACC
AAACGTTGAAGACGTAAAACAGGGCGTTATAGCTTACAAGATTGCCGCACACGCCGCGGACATAGCAAAGCACTGGCCCG
GAGCAAGAGACTGGGATCTCGCCATGTCCATAGCAAGGTATAACTTTGACTGGAACAAACAGTTTGAACTCGCTATGGAC
CCAGAAACCGCGAGGGCGTACCACGACGAGACACTGCCTCAGGAAGGATACAAAACCGCTAAATTCTGTTCTATGTGCGG
ACCGGAGTTCTGCTCTTACAAGATATCCCAGAAGGTTCAGGAAAAAGTTTCTCCTGAAGAATTAATAGAAAACGGGAACT
GGGTAGCCCCTTAA

Protein sequence :
MLRAEWVEKRKRFKNKTQMHLARQGIITEEMEYVAKREGLHPEFVRQEVARGRMIIPANINHLHLEPMCIGINSKVKVNA
NIGNSGLASDIPTEVEKAKVAIKYGADTIMDLSTGEAIKETREAIINVSTVPVGTVPIYEAWKIAKGNVKELTVDLILDV
IEEQARQGVSYMTIHAGILREHLPLVQHRVMGIVSRGGAILAQWMAEHGKQNPLYEHFDKICEIFKKYDVSFSLGDALRP
GCIEDATDDAQLAELKVLGELVEKAWKHDVQAMVEGPGHVPLHQVEFNMKIQQEWCHEAPFYVLGPLVLDVAPGYDHIGS
AIGGALAGWAGAAMLCYITPKEHLGLPNVEDVKQGVIAYKIAAHAADIAKHWPGARDWDLAMSIARYNFDWNKQFELAMD
PETARAYHDETLPQEGYKTAKFCSMCGPEFCSYKISQKVQEKVSPEELIENGNWVAP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 2e-109 62
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 2e-109 62
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 4e-107 59