Gene Information

Name : kpsU (aq_692)
Accession : NP_213474.1
Strain : Aquifex aeolicus VF5
Genome accession: NC_000918
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 470797 - 471501 bp
Length : 705 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAGAAGAGCTGTAATCATACCTGCAAGACTAGGCTCAACAAGGCTAAAGGAAAAACCTTTAAAAAATTTACTCGGAAA
GCCCCTCATAAGGTGGGTAGTTGAAGGACTCGTAAAAACGGGAGAGAGGGTAATCCTCGCTACGGACAGCGAAAGGGTAA
AGGAAGTGGTTGAGGACCTATGTGAAGTTTTCCTTACCCCCTCGGACCTGCCCTCGGGCAGTGACAGAGTTCTGTACGTC
GTTAGAGATTTGGATGTTGACTTAATTATCAATTATCAGGGAGATGAGCCCTTTGTTTACGAGGAAGATATAAAATTGAT
ATTTAGAGAACTTGAAAAGGGAGAAAGAGTTGTAACCCTTGCAAGGAAGGACAAGGAGGCTTACGAGAGACCTGAAGACG
TGAAGGTGGTTCTGGACAGGGAAGGATACGCCCTTTACTTTTCCCGCTCACCTATCCCATACTTTAGGAAAAATGATACA
TTTTATCCTTTAAAACACGTAGGGATTTACGGCTTCAGAAAGGAAACTTTAATGGAGTTCGGCGCTATGCCTCCCTCAAA
ACTTGAACAAATAGAAGGACTTGAACAGTTAAGGCTTTTAGAGAACGGAATAAAGATAAAGGTTTTAATTACGGAGAATT
ACTACCACGGAGTTGATACGGAGGAGGACTTAAAGATAGTGGAAGAAAAGTTAAAAAATTTATAA

Protein sequence :
MRRAVIIPARLGSTRLKEKPLKNLLGKPLIRWVVEGLVKTGERVILATDSERVKEVVEDLCEVFLTPSDLPSGSDRVLYV
VRDLDVDLIINYQGDEPFVYEEDIKLIFRELEKGERVVTLARKDKEAYERPEDVKVVLDREGYALYFSRSPIPYFRKNDT
FYPLKHVGIYGFRKETLMEFGAMPPSKLEQIEGLEQLRLLENGIKIKVLITENYYHGVDTEEDLKIVEEKLKNL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-25 41
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 8e-26 41