Gene Information

Name : serS (aq_298)
Accession : NP_213207.1
Strain : Aquifex aeolicus VF5
Genome accession: NC_000918
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 193284 - 194561 bp
Length : 1278 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATAGATATAAACCTCATTAGGGAAAAACCCGATTACGTGAAGGAAAGACTCGCAACGAGGGATAAAGAACTCGTTTC
CTTAGTTGACAAAGTTCTTGAACTTGACAAAAGGAGAAGGGAAATAATAAAAAGACTTGAAGCCTTAAGGAGTGAGAGGA
ATAAACTGAGCAAGGAAATAGGAAAACTAAAGAGGGAAGGCAAGGACACCACGGAAATACAAAACAGAGTAAAGGAATTG
AAAGAGGAAATAGACAGACTTGAGGAAGAGTTAAGGAAAGTGGAAGAGGAGTTAAAGAACACGCTCCTCTGGATACCTAA
CCTCCCCCACCCGAGTGTTCCAGTGGGAGAGGACGAAAAGGACAACGTGGAAGTAAGGAGATGGGGAGAGCCGAGGAAGT
TTGATTTTGAACCAAAACCTCACTGGGAAATAGGGGAAAGATTGGGAATTCTCGACTTCAAGAGGGGTGCAAAGCTCTCT
GGAAGCAGGTTTACCGTAATAGCCGGCTGGGGTGCGAGATTAGAAAGGGCGCTTATAAACTTTATGCTGGACCTCCACAC
CAAAAAGGGCTACAAGGAAATATGTCCTCCCCATTTGGTAAAGCCGGAAATCTTAATAGGAACTGGACAGCTACCGAAGT
TTGAAGAGGACCTCTACAAGTGTGAAAGGGATAACCTCTACCTGATACCCACCGCGGAAGTTCCCCTGACAAACCTCTAC
AGAGAAGAGATACTCAAGGAAGAGAACCTTCCCATATATCTCACTGCGTACACGCCCTGTTACAGAAGGGAAGCGGGAGC
ATACGGAAAAGACATAAGGGGGATAATAAGACAGCACCAGTTTGACAAAGTAGAACTTGTGAAGATAGTCCACCCGGACA
CTTCTTACGATGAGCTTGAGAAACTTGTAAAAGACGCTGAAGAAGTTCTCCAGCTTCTCGGACTTCCATACAGGGTGGTG
GAACTCTGCACGGGTGACCTCGGTTTTTCCGCCGCAAAGACCTACGACATAGAAGTGTGGTTTCCCTCTCAAAACAAGTA
CAGGGAAATCTCCTCCTGCTCCAACTGCGAGGACTTTCAAGCGAGGAGGATGAACACGCGCTTTAAGGACTCAAAAACTG
GTAAAAATAGGTTCGTACACACTCTGAACGGCTCCGGACTTGCGGTGGGAAGGACTCTGGCGGCTATATTGGAAAACTAC
CAACAGGAAGACGGTAGCGTAGTAGTTCCGGAAGTTCTCAGAGATTACGTGGGAACGGACGTGATTAGACCCGAGTAA

Protein sequence :
MIDINLIREKPDYVKERLATRDKELVSLVDKVLELDKRRREIIKRLEALRSERNKLSKEIGKLKREGKDTTEIQNRVKEL
KEEIDRLEEELRKVEEELKNTLLWIPNLPHPSVPVGEDEKDNVEVRRWGEPRKFDFEPKPHWEIGERLGILDFKRGAKLS
GSRFTVIAGWGARLERALINFMLDLHTKKGYKEICPPHLVKPEILIGTGQLPKFEEDLYKCERDNLYLIPTAEVPLTNLY
REEILKEENLPIYLTAYTPCYRREAGAYGKDIRGIIRQHQFDKVELVKIVHPDTSYDELEKLVKDAEEVLQLLGLPYRVV
ELCTGDLGFSAAKTYDIEVWFPSQNKYREISSCSNCEDFQARRMNTRFKDSKTGKNRFVHTLNGSGLAVGRTLAAILENY
QQEDGSVVVPEVLRDYVGTDVIRPE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 6e-109 56