Gene Information

Name : smpB (aq_287)
Accession : NP_213200.1
Strain : Aquifex aeolicus VF5
Genome accession: NC_000918
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 186900 - 187373 bp
Length : 474 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGGCAAAAGCGACAAAATTATCCCTATAGCTGAAAACAAGGAAGCAAAAGCCAAGTACGACATACTTGAGACCTACGA
AGCGGGAATAGTCTTGAAAGGTTCCGAGGTAAAATCCCTGAGGGAAAAGGGAACCGTTTCCTTTAAGGATAGTTTCGTAA
GGATAGAAAACGGAGAGGCGTGGCTCTACAACCTCTACATAGCCCCGTATAAACACGCGACTATAGAAAACCACGATCCA
TTAAGAAAGAGAAAGCTCCTTCTTCACAAAAGGGAGATAATGAGGCTCTACGGAAAAGTTCAGGAAAAGGGCTACACTAT
AATTCCCTTAAAGCTCTATTGGAAGAACAACAAAGTGAAGGTTCTGATAGCCCTTGCAAAGGGTAAGAAGCTCTACGACA
GGAGGAGAGAACTCAAAGAAAAAGCTATGAAGAGGGAACTCGAAAGAGAGTTTAAAGGTAAAATACACCTCTGA

Protein sequence :
MGKSDKIIPIAENKEAKAKYDILETYEAGIVLKGSEVKSLREKGTVSFKDSFVRIENGEAWLYNLYIAPYKHATIENHDP
LRKRKLLLHKREIMRLYGKVQEKGYTIIPLKLYWKNNKVKVLIALAKGKKLYDRRRELKEKAMKRELEREFKGKIHL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 4e-27 54
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 1e-22 48
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 2e-16 43