Gene Information

Name : hemC (aq_263)
Accession : NP_213181.1
Strain : Aquifex aeolicus VF5
Genome accession: NC_000918
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 168918 - 169889 bp
Length : 972 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
GTGTACCCCGTTTGGGGTACCGAGGGTTCGAATCCCTCCCCTTCCGCCATTCCCGCTATGAAAATCAGGATTGGAACTAG
GAAGAGTAAACTCGCCCTGTGGCAGGCGAATTACGTAAAAGATTTCTTAGAAAAACACTGGGGTGTTGAAGTAGAACTCG
TAAAGATAACAACAACGGGAGACAAAATTACCGATGTTCCCCTTGCAAAAATAGGAGGAAAAGGACTTTTTGTTAAGGAG
ATAGAAAAAGCGTTGCTCGAGGGTAGTATAGACCTTGCGGTCCACTCCTTGAAGGACGTCCCTATGGTTATACCCAAAGG
TCTGAAACTCGGAGCTATAACAAAGAGGGAAAACCCCTACGACGTTTTAATATCGCGAAGCGGAAAGAAACTTTATGAAC
TTCCCTCGGGTTCTGTTATAGGTACTTCTTCTCTAAGGAGACAGGTTCAGATAAAGAAAAGGAGAAGGGATTTAAAGGTA
GAAGTCCTAAGGGGAAACGTGGACACTAGAATGAGGAAACTGAAGGAAGGACTCTACGACGCAGTAATCCTAGCATACGC
AGGTGTAAAGAGGATGGGTTACGAAAGTGAGATAACGGAAGTGCTTGAAGACTTCATCCCTGCGGTAGGACAGGGCTCTC
TCGCAATAGAAATCAGAGAAGGAGATAAAAGGATAGAGGAGTTAATAAAACCTCTAAACAACGAGGAGAGTTTTCTCTGC
GCAATTGCGGAAAGGACGTTCTTAAGGAGGCTTGAGGGAGGATGTCAGGTTCCCGTGGGAGCCTTTGCTAAGATAGAAAA
CGGAACTCTTAAGATGAAAGCCTTTATATCTGACATTGAGGCTGAAAGGTATATAGAAGGGTATAGAGAAGGAAATCCCG
AGGAGGCAGAAAAACTGGGACTTTCACTTGCAGAAGAACTCTTGAAAAAAGGCGGGGAGGAAATATTGAAGGAAATATAC
TCTTCCCAATGA

Protein sequence :
MYPVWGTEGSNPSPSAIPAMKIRIGTRKSKLALWQANYVKDFLEKHWGVEVELVKITTTGDKITDVPLAKIGGKGLFVKE
IEKALLEGSIDLAVHSLKDVPMVIPKGLKLGAITKRENPYDVLISRSGKKLYELPSGSVIGTSSLRRQVQIKKRRRDLKV
EVLRGNVDTRMRKLKEGLYDAVILAYAGVKRMGYESEITEVLEDFIPAVGQGSLAIEIREGDKRIEELIKPLNNEESFLC
AIAERTFLRRLEGGCQVPVGAFAKIENGTLKMKAFISDIEAERYIEGYREGNPEEAEKLGLSLAEELLKKGGEEILKEIY
SSQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-59 50
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-59 50