Gene Information

Name : MTH1576 (MTH1576)
Accession : NP_276688.1
Strain : Methanothermobacter thermautotrophicus Delta H
Genome accession: NC_000916
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 1443295 - 1444569 bp
Length : 1275 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
GTGACTCAGATGGAAGAAGCAAGAAAGGGCAATATAACCCCTGAGATGGAGGAGGTTGCCCGGAAAGAAAACCTGGACAT
TCAGATGCTTATTAGGGGTATTGCAAACGGTCGAATTGTGATACCCTCCAATATTAATCGGGAATCATCACCCTGCGGCA
TAGGGGAAAATCTTTCAACAAAGATCAATGCAAATATCGGTTCATCCTCAAAAATGGAGGACATTGAACTGGAGGTTGAT
AAGGCACTTGCAGCTGTCGAATACGGTGCAGATGCTGTCATGGACCTCAGCACAGGCCCCATGCTGAGGGATGTCAGGAA
AGCGGTCCTGGAGGCTGTTGACGTTCCTGTGGGCACGGTACCCATCTACGAGGCCGGTGTCGAGGCCTTCATGTCAGATG
GAGCCGTGGTGGACATGGATGAGGATGACATGTTCAGGGCCATAGAGAACCAGGCCCGGGATGGGGTTGACTTCATGACC
GTGCACTCAGGAATCACCCTGGAAACCGTTGAAAGGGCTCAGAGATCAGGGAGGATAATGGGAATAGTTAGCCGGGGAGG
AGCATTCCTTGCAGCCTGGATAATGCAGAATCAGGAGGAGAATCCTCTCTACAGCAACTATGAGTACCTCCTTGAAGTGG
CCTACGAGTATGATGTCACACTCAGCCTCGGGGATGGCCTCAGGCCGGGGTGCCTGGCAGACGCTTCTGATATACCCCAG
ATCAGTGAGCTCCTCACACTTGCAGAACTCGTTGAGAGGGCACGTGATGCAGATGTTCAGTGCATGGTTGAGGGGCCCGG
TCACATGCCCCTTGACCAGATAGCCGCCAACATGAAGATACAGAAGGAGGTCTGCGACGGCGCACCCTTCTATGTCCTTG
GACCCATAGTCACAGACATGGCACCGGGTTATGACCATATAAGCGCAGCCATAGGCGGGGCCGTCGCTGCAATGAACGGG
GCGGACTTCCTCTGTTACGTCACACCGGCAGAGCACCTGGCGATACCGGGGGTTCAGGATGTTATTGAGGGTGTCATTGC
ATCAAGGATAGCTGCCCAGGCTGCAGACGCCGCCAGAAAATTACCGGGCGCATGGGATTCTGAACTTGAGATGGCTGATG
CAAGAAGGTCCTTTGACTGGGATAAACAGTTCAAACTGGCCTTTGACTCAAAAAAACCATATGAATACAGGATGCAGTGC
CCAATTGAGGATTCAGAGATGTGCTCAATGTGTGGCGAATACTGCGCCCTCAGGATACTGCGTGAAGACAGATGA

Protein sequence :
MTQMEEARKGNITPEMEEVARKENLDIQMLIRGIANGRIVIPSNINRESSPCGIGENLSTKINANIGSSSKMEDIELEVD
KALAAVEYGADAVMDLSTGPMLRDVRKAVLEAVDVPVGTVPIYEAGVEAFMSDGAVVDMDEDDMFRAIENQARDGVDFMT
VHSGITLETVERAQRSGRIMGIVSRGGAFLAAWIMQNQEENPLYSNYEYLLEVAYEYDVTLSLGDGLRPGCLADASDIPQ
ISELLTLAELVERARDADVQCMVEGPGHMPLDQIAANMKIQKEVCDGAPFYVLGPIVTDMAPGYDHISAAIGGAVAAMNG
ADFLCYVTPAEHLAIPGVQDVIEGVIASRIAAQAADAARKLPGAWDSELEMADARRSFDWDKQFKLAFDSKKPYEYRMQC
PIEDSEMCSMCGEYCALRILREDR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 5e-71 43
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 5e-71 43