Gene Information

Name : HP0524 (HP0524)
Accession : NP_207320.1
Strain : Helicobacter pylori 26695
Genome accession: NC_000915
Putative virulence/resistance : Virulence
Product : cag pathogenicity island protein (cag5)
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG3505
EC number : -
Position : 550217 - 552463 bp
Length : 2247 bp
Strand : -
Note : similar to GP:1800161 percent identity: 99.06; identified by sequence similarity

DNA sequence :
ATGGAAGACTTTTTGTATAACACCTTATATTTCATAGAGGATTATAAGTTGGTTGTTATTTTTAGTTTCATAGGGTTAAT
AGCGTTATTTTTTCTTTACAAATTCATAAAAGCTCAAAAAAAGGCTTTTAAAGATAAAGCTAACCAGCCTCAAAAGAAAA
AAAGCTTTAAAGAAATCATTATAGATGGGCTGAAAGAAAGGGTTAAAACCTTTGGCTTTTGGTTGCAAGCTATACTATTA
CTATCCTATTCTTTTATCACATCAGGATTATTTTTCTTGATTCTCTTAGGTAATTTTTATGATGATAATCGATCGCCTGA
GAGCGATGATGATCTTTTTGATATATGGATCTATGCGATACAAGATTTTCCTAATTACTATTTTAAAGCGCTTGGTTTTA
GTTCACTCAAGATTTATGGGTTCAATATATCCTTAGTCGTATATGGTTCTATTTTATGCTCTTATATCTTCATTACCTTT
TTTGTGTGGTTCTTAAAATACTTAACTCGGACTAGAGATATAGGAGCGAATAAAAAAGTTGATGATCTCTTTGGTAGCGC
GAGTTGGGAAACTGAAGAGAAAATGATCAAAGCCAAACTCATCACGCCCAACAATAAAAAACGCGCCTTTGACAAACGAG
AGGTGATTGTAGGCAGGCGTGGCTTGGGGGATTTTATCGCTTACGCAGGGCAGGCGTTCATTGGCTTGATTGCTCCTACT
AGAAGCGGTAAGGGGGTGGGTTTCATCATGCCCAATATGATCAATTATCCTCAAAATATCGTTGTGTTTGACCCTAAAGC
TGACACTATGGAGACTTGCGGAAAAATCAGAGAAAAACGCTTCAACCAAAAAGTGTTCATCTATGAACCTTTCTCCTTAA
AAACACACCGATTTAATCCTTTCGCTTATGTGGATTTTGGTAATGATGTGGTTTTGACCGAAGACATACTCTCTCAAATT
GACACACGCCTAAAAGGGCATGGCATGGTGGCTAGTGGAGGGGATTTTTCCACTCAAATCTTTGGATTAGCAAAGCTCGT
GTTCCCTGAAAGACCTAATGAAAAAGATCCTTTCTTTAGCAATCAAGCGCGAAATCTTTTTGTCATCAATTGCAATATTT
ACAGGGATCTCATGTGGACTAAAAAGGGGCTTGAGTTTGTCAAAAGAAAAAAAATCATCATGCCTGAAACACCCACGATG
TTTTTCATAGGTTCTATGGCAAGCGGGATCAACTTGATTGATGAAGACACAAACATGGAAAAAGTCGTGTCTTTAATGGA
ATTTTTTGGAGGTGAAGAAGATAAGAGTGGCGATAATCTAAGAGTGCTTAGTCCTGCCACTAGAAACATGTGGAATAGCT
TCAAGACAATGGGCGGCGCTAGAGAAACTTATAGCTCGGTTCAAGGGGTATACACTTCAGCCTTTGCGCCTTATAATAAC
GCAATGATTAGAAATTTCACGAGCGCCAATGATTTTGATTTCAGGCGTTTAAGGATCGATGAAGTGAGTATTGGTGTGAT
CGCTAATCCTAAAGAAAGCACTATTGTTGGACCGATATTAGAGCTGTTTTTCAATGTGATGATTTATAGCAATTTGATTC
TGCCAATCCATGATCCACAGTGCAAAAGAAGTTGCTTGATGCTCATGGACGAATTCACTTTATGTGGCTATTTAGAGACC
TTTGTTAAAGCGGTAGGGATTATGGCAGAATACAACATGCGCCCCGCTTTTGTGTTTCAAAGTAAGGCGCAACTAGAGAA
TGACCCCCCACTTGGTTATGGTAGGAATGGCGCTAAGACTATTTTAGACAACCTTTCTTTGAATATGTATTATGGGATTA
ACAACGATAACTACTATGAACATTTTGAAAAACTTTCTAAGGTATTAGGGAAATACACAAGGCAAGACGTGAGCCGAAGC
ATTGATGATAATACAGGTAAGACCAACACTTCTATCAGCAACAAAGAGCGGTTTTTGATGACCCCTGATGAATTGATGAC
TATGGGCGATGAGCTTATCATTCTAGAGAATACGCTCAAACCTATCAAGTGCCACAAGGCGCTTTACTATGATGATCCAT
TCTTCACCGATGAACTCATTAAGGTAAGTCCAAGCTTGAGCAAGAAATACAAATTGGGGAAAGTGCCTAATCAAGCAACT
TTCTATGATGATTTGCAAGCCGCTAAAACTAGAGGTGAATTGAGTTATGATAAATCTTTAGTGCCTGTGGGTTCAAGTGA
ACTGTGA

Protein sequence :
MEDFLYNTLYFIEDYKLVVIFSFIGLIALFFLYKFIKAQKKAFKDKANQPQKKKSFKEIIIDGLKERVKTFGFWLQAILL
LSYSFITSGLFFLILLGNFYDDNRSPESDDDLFDIWIYAIQDFPNYYFKALGFSSLKIYGFNISLVVYGSILCSYIFITF
FVWFLKYLTRTRDIGANKKVDDLFGSASWETEEKMIKAKLITPNNKKRAFDKREVIVGRRGLGDFIAYAGQAFIGLIAPT
RSGKGVGFIMPNMINYPQNIVVFDPKADTMETCGKIREKRFNQKVFIYEPFSLKTHRFNPFAYVDFGNDVVLTEDILSQI
DTRLKGHGMVASGGDFSTQIFGLAKLVFPERPNEKDPFFSNQARNLFVINCNIYRDLMWTKKGLEFVKRKKIIMPETPTM
FFIGSMASGINLIDEDTNMEKVVSLMEFFGGEEDKSGDNLRVLSPATRNMWNSFKTMGGARETYSSVQGVYTSAFAPYNN
AMIRNFTSANDFDFRRLRIDEVSIGVIANPKESTIVGPILELFFNVMIYSNLILPIHDPQCKRSCLMLMDEFTLCGYLET
FVKAVGIMAEYNMRPAFVFQSKAQLENDPPLGYGRNGAKTILDNLSLNMYYGINNDNYYEHFEKLSKVLGKYTRQDVSRS
IDDNTGKTNTSISNKERFLMTPDELMTMGDELIILENTLKPIKCHKALYYDDPFFTDELIKVSPSLSKKYKLGKVPNQAT
FYDDLQAAKTRGELSYDKSLVPVGSSEL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
HP0524 NP_207320.1 cag pathogenicity island protein (cag5) Virulence cag PAI Protein 0.0 100
cag5 AAR03858.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD13967.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD14023.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13803.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005774545.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03887.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD13776.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005779066.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13995.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13830.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
virD4 NP_223191.1 cag island protein, DNA transfer protein Virulence cag PAI Protein 0.0 99
cag5 AAR03916.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD13912.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_003728740.1 cag pathogenicity island protein beta Virulence cag PAI Protein 0.0 99
cag-beta AAF80195.1 Cag-beta Virulence cag PAI Protein 0.0 99
cag5 AAR03947.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD13885.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13857.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
cag5 YP_005775727.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
HP0524 BAD14049.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
cag5 YP_005777268.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
HP0524 BAD13940.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HP0524 NP_207320.1 cag pathogenicity island protein (cag5) VFG0284 Protein 0.0 100