Gene Information

Name : HP0522 (HP0522)
Accession : NP_207318.1
Strain : Helicobacter pylori 26695
Genome accession: NC_000915
Putative virulence/resistance : Virulence
Product : cag pathogenicity island protein (cag3)
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 548134 - 549579 bp
Length : 1446 bp
Strand : +
Note : similar to GP:1800159 percent identity: 98.13; identified by sequence similarity

DNA sequence : 
ATGTTTAGAAAACTAGCAACCGCTGTATCGCTCATAGGCTTACTAACCTCTAACACTCTTTATGCTAAAGAAATAAGTGA
AGCCGATAAGGTCATTAAGGCCACTAAAGAAACTAAAGAGACCAAGAAAGAAGCTAAACGACTCAAAAAAGAAGCTAAAC
AGCGCCAACAGATCCCTGATCATAAGAAACCTCAATATGTCTCTGTTGATGACACAAAAACTCAAGCGCTGTTTGATATA
TACGACACCTTGAATGTGAATGACAAAAGCTTTGGGGATTGGTTTGGTAATAGCGCTTTGAAAGACAAAACCTATCTCTA
CGCTATGGATCTATTGGATTACAACAACTATTTATCCATAGAAAACCCCATTATCAAAACAAGAGCAATGGGAACTTATG
CGGATTTGATTATCATCACAGGCTCATTAGAGCAAGTCAATGGGTATTACAACATTCTAAAAGCGCTCAACAAACGCAAC
GCTAAGTTTGTGTTAAAAATCAATGAGAACATGCCTTATGCCCAAGCGACTTTTTTAAGAGTGCCAAAAAGAAGCGATCC
TAATGCCCACACGCTTGATAAGGGAGCGTCAATTGATGAGAATAAGCTTTTTGAACAACAAAAGAAAATGTATTTCAATT
ACGCTAACGATGTGATCTGCAGACCCGATGATGAAGTGTGTTCGCCCCTAAGAGATGAGATGGTAGCTATGCCCACTAGC
GATAGCGTTACTCAAAAACCCAATATCATTGCTCCTTATAGCTTGTATAGACTAAAAGAGACAAATAACGCCAATGAGGC
CCAACCATCACCTTATGCCACTCAAACCGCTCCCGAAAACAGCAAAGAGAAGCTCATAGAAGAGCTAATCGCTAACTCCC
AACTCGTAGCCAATGAAGAAGAGAGGGAAAAGAAACTCTTAGCAGAAAAAGAAAAACAAGAGGCTGAATTGGCTAAATAT
AAGCTCAAAGACTTAGAAAATCAAAAGAAACTAAAAGCTTTAGAAGCAGAGTTGAAAAAGAAAAACGCTAAGAAACCTAG
AGTAGTGGAAGTGCCTGTTTCTCCTCAAACAAGTAATTCTGATGAAACAATGAGAGTTGTCAAAGAAAAAGAGAACTATA
ATGGGTTATTAGTGGATAAGGAGACCACGATCAAAAGAAGCTATGAGGGGACTTTGATCAGTGAAAATTCTTACAGCAAA
AAAACACCTCTCAACCCTAATGACTTGAGGAGCTTAGAAGAAGAAATTAAGAGCTACTATATCAAGTCTAATGGCTTGTG
TTATACTAATGGCATTAACCTCTATGTAAAAATCAAAAACGACCCCTATAAAGAGGGAATGCTGTGTGGTTATGAGAGCG
TTCAAAATCTGCTCTCACCTCTAAAGGACAAGCTCAAATACGACAAACAAAAGTTACAAAAAGCGTTACTGAAAGATTCA
AAGTAA

Protein sequence : 
MFRKLATAVSLIGLLTSNTLYAKEISEADKVIKATKETKETKKEAKRLKKEAKQRQQIPDHKKPQYVSVDDTKTQALFDI
YDTLNVNDKSFGDWFGNSALKDKTYLYAMDLLDYNNYLSIENPIIKTRAMGTYADLIIITGSLEQVNGYYNILKALNKRN
AKFVLKINENMPYAQATFLRVPKRSDPNAHTLDKGASIDENKLFEQQKKMYFNYANDVICRPDDEVCSPLRDEMVAMPTS
DSVTQKPNIIAPYSLYRLKETNNANEAQPSPYATQTAPENSKEKLIEELIANSQLVANEEEREKKLLAEKEKQEAELAKY
KLKDLENQKKLKALEAELKKKNAKKPRVVEVPVSPQTSNSDETMRVVKEKENYNGLLVDKETTIKRSYEGTLISENSYSK
KTPLNPNDLRSLEEEIKSYYIKSNGLCYTNGINLYVKIKNDPYKEGMLCGYESVQNLLSPLKDKLKYDKQKLQKALLKDS
K

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
HP0522 NP_207318.1 cag pathogenicity island protein (cag3) Virulence cag PAI Protein 3e-171 100
cag3 AAR03914.1 Cag3 Virulence cag PAI Protein 1e-169 99
cag-delta AAF80193.1 Cag-delta Virulence cag PAI Protein 4e-169 99
cag3 AAR03945.1 Cag3 Virulence cag PAI Protein 7e-169 99
HP0521 BAD13993.1 cag pathogenicity island protein Virulence cag PAI Protein 3e-167 99
HP0521 BAD13965.1 cag pathogenicity island protein Virulence cag PAI Protein 6e-167 99
cag3 AGC69793.1 cag pathogenicity island protein 3 Virulence cag PAI Protein 2e-169 98
cag3 AAR03854.1 Cag3 Virulence cag PAI Protein 9e-169 98
cag3 YP_003728744.1 cag pathogenicity island protein delta Virulence cag PAI Protein 3e-169 98
cag3 AAR03885.1 Cag3 Virulence cag PAI Protein 4e-166 98
HP0522 BAD13801.1 cag pathogenicity island protein Virulence cag PAI Protein 7e-168 97
HP0522 BAD13883.1 cag pathogenicity island protein Virulence cag PAI Protein 7e-168 97
HP0522 BAD14047.1 cag pathogenicity island protein Virulence cag PAI Protein 4e-168 97
HP0522 BAD13910.1 cag pathogenicity island protein Virulence cag PAI Protein 2e-166 97
HP0522 BAD14021.1 cag pathogenicity island protein Virulence cag PAI Protein 3e-168 97
HP0522 BAD13855.1 cag pathogenicity island protein Virulence cag PAI Protein 9e-167 97
cag3 YP_005775725.1 cag pathogenicity island protein Virulence cag PAI Protein 1e-166 97
cag3 YP_005777266.1 cag pathogenicity island protein Virulence cag PAI Protein 2e-167 97
HP0522 BAD13774.1 cag pathogenicity island protein Virulence cag PAI Protein 9e-169 97
cag3 YP_005774547.1 cag pathogenicity island protein Virulence cag PAI Protein 1e-167 97
HP0522 BAD13938.1 cag pathogenicity island protein Virulence cag PAI Protein 1e-167 97
cag3 YP_005779068.1 cag pathogenicity island protein Virulence cag PAI Protein 1e-168 97
HP0522 BAD13828.1 cag pathogenicity island protein Virulence cag PAI Protein 9e-168 97
orf8 NP_223189.1 cag island protein Virulence cag PAI Protein 1e-164 95

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HP0522 NP_207318.1 cag pathogenicity island protein (cag3) VFG0282 Protein 1e-171 100