Gene Information

Name : HP0512 (HP0512)
Accession : NP_207309.1
Strain : Helicobacter pylori 26695
Genome accession: NC_000915
Putative virulence/resistance : Virulence
Product : glutamine synthetase (glnA)
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0174
EC number : -
Position : 538237 - 539682 bp
Length : 1446 bp
Strand : -
Note : similar to GB:X05173 SP:P06711 GB:J01618 GB:M13746 GB:V00282 percent identity: 49.24; identified by sequence similarity

DNA sequence :
ATGATAGTAAGAACTCAAAATAGTGAAAGCAAGATCAAAGAATTTTTTGAATTTTGCAAAGAAAATGAAGTGGAATTTGT
GGATTTTAGATTCAGCGATATTAAAGGCACTTGGAATCACATCGCTTATTCTTTTGGGGCTTTAACGCATGGCATGCTTA
AAGAGGGGATTCCTTTTGATGCGAGTTGTTTTAAAGGCTGGCAAGGCATTGAACACTCCGATATGATTTTAACCCCCGAC
TTGGTGCGTTATTTCATTGACCCTTTTAGCGCGGATGTGAGCGTGGTCGTGTTTTGCGATGTGTATGATGTGTATAAAAA
CCAGCCTTATGAGAAATGCCCTAGAAGTATCGCTAAAAAAGCCTTACAACATTTAAAAGATTCAGGTTTGGGCGATGTGG
CTTATTTTGGCGCGGAGAATGAATTTTTTATCTTTGATTCCATTAAAATTAAAGACGCTTCCAATTCCCAATACTACGAA
GTGGATAGCGAAGAGGGCGAATGGAATAGGGATAGAAGCTTTGAAAACGGCGTCAATTTTGGGCATAGACCGGGCAAACA
AGGGGGTTATATGCCTGTGCCGCCAACGGATACGATGATGGATATTCGCACAGAAATTGTGAAAGTCTTAAACCAAGTGG
GGCTAGAAACTTTTGTCGTCCATCATGAAGTCGCGCAAGCGCAAGGCGAAGTGGGCGTGAAATTTGGGGATTTAGTGGAA
GCGGCTGATAATGTCCAAAAACTCAAATATGTGGTTAAAATGGTCGCTCATTTAAACGGGAAAACCGCCACTTTCATGCC
AAAACCTTTATACGGGGATAACGGGAGCGGGATGCACACCCATGTGAGCGTTTGGAAAAACAACGAAAACCTTTTTAGCG
GCGAAACTTACAAGGGCTTGAGCGAGTTTGCCTTGCATTTTTTAGGGGGCGTGTTGCGCCACGCTAGAGGATTGGCCGCT
TTCACTAACGCTTCCACTAATTCTTACAAACGCCTAATTCCGGGATATGAAGCCCCATCCATTTTAACTTATTCGGCTAA
TAACAGGAGCGCGAGCGTGCGTATCCCTTATGGGATTTCTAAAAATAGTGCTAGGTTTGAATTCAGATTCCCGGACAGCT
CATCAAACCCCTACTTGGCTTTTGCAGCGATTTTAATGGCAGGCATGGATGGCGTTAAAAATAAGATTGATCCCGGCGAG
GCGATGGATATTAACCTTTTCAAATTGACTTTAGATGAAATTAGGGAAAAAGGTATCAAACAAATGCCCCACACTTTAAG
GAGATCGTTAGAAGAAATGCTAGCCGATAAGCAGTATTTAAAAGAAAGTCAGGTCTTTAGCGAAGAATTTATTCAAGCCT
ATCAGTCTCTTAAATTCAACGCTGAAGTGTTCCCATGGGAGAGCAAGCCCCATCCTTTTGAATTTATCACCACTTATTCA
TGCTAA

Protein sequence :
MIVRTQNSESKIKEFFEFCKENEVEFVDFRFSDIKGTWNHIAYSFGALTHGMLKEGIPFDASCFKGWQGIEHSDMILTPD
LVRYFIDPFSADVSVVVFCDVYDVYKNQPYEKCPRSIAKKALQHLKDSGLGDVAYFGAENEFFIFDSIKIKDASNSQYYE
VDSEEGEWNRDRSFENGVNFGHRPGKQGGYMPVPPTDTMMDIRTEIVKVLNQVGLETFVVHHEVAQAQGEVGVKFGDLVE
AADNVQKLKYVVKMVAHLNGKTATFMPKPLYGDNGSGMHTHVSVWKNNENLFSGETYKGLSEFALHFLGGVLRHARGLAA
FTNASTNSYKRLIPGYEAPSILTYSANNRSASVRIPYGISKNSARFEFRFPDSSSNPYLAFAAILMAGMDGVKNKIDPGE
AMDINLFKLTLDEIREKGIKQMPHTLRRSLEEMLADKQYLKESQVFSEEFIQAYQSLKFNAEVFPWESKPHPFEFITTYS
C

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 0.0 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HP0512 NP_207309.1 glutamine synthetase (glnA) VFG1399 Protein 4e-88 44