Gene Information

Name : hemC (HP0237)
Accession : NP_207035.1
Strain : Helicobacter pylori 26695
Genome accession: NC_000915
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 246629 - 247549 bp
Length : 921 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
GTGGGAAATTTAGTGATTGGCTCTAGGGGGAGCGAATTAGCCTTATGGCAAGCGAATCACATTAAAGAACGCCTGAAAAA
AGAATGCTTGATAGAAAGCGAAATTCAAATCGTTAAGACTAAGGGCGATAAAATCTTAGACACCCCTTTAAATAAGATCG
GCGGTAAGGGGCTATTCACTAAGGAATTAGAAGAATTGCTTTTAAAGGGCGCAATTGATTTGGCGGTGCATTCTTTAAAA
GACGTGCCGGTCGTGTTTGAAAAGGGGTTAGACTTGGCATGCATCACCAAAAGGGCTGATGTGAGGGACACTTTTTTAAG
CGTGAAATTCCCTGATTTGATGAGTTTGCCTAAAGGGGCAAAGGTTGGCACGACTTCTTTAAGGCGCTCTATGCAGATCA
AATTAAAGCGCCAGGATTTGGACACAGAAAGCTTGAGAGGGAATGTCCAAACCCGTTTGAAAAAGCTTGAATGCGGAGAA
TTTGACGCTATCATTTTAGCTGAAGCCGGGTTGTGCCGCCTAGAAATTCAAGGAGCGAAATACCGCAAGGCTTTTAGCGT
AGAAGAAATGATTCCTAGCATGGGTCAGGGGGCTTTAGGGGTAGAAATGCTCAAAAACCACAAGCATTTTGCCACGCTTC
AAAAACTCAACGACGAGAAAAGCGCGTTTTGCTGCCGTTTAGAAAGGGAGTTTATCAAGGGGCTTAATGGAGGGTGTCAG
ATCCCTATAGGCGTGCATGCGAGTTTAATGGGCGATAGGGTTAAAATCCAGGCGGTTTTAGGCTTGCCTAACGGGAAAGA
AGTCATTACTAAAGAAAAACAAGGGGATAAAACTAAAGCGTTTGATTTAGTTCAAGAGCTTTTAGAAGAATTTTTGCAAA
GCGGGGCTAAAGAGATTTTAGAAAAGGCGCAGTTGTTTTAA

Protein sequence : 
MGNLVIGSRGSELALWQANHIKERLKKECLIESEIQIVKTKGDKILDTPLNKIGGKGLFTKELEELLLKGAIDLAVHSLK
DVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGAKVGTTSLRRSMQIKLKRQDLDTESLRGNVQTRLKKLECGE
FDAIILAEAGLCRLEIQGAKYRKAFSVEEMIPSMGQGALGVEMLKNHKHFATLQKLNDEKSAFCCRLEREFIKGLNGGCQ
IPIGVHASLMGDRVKIQAVLGLPNGKEVITKEKQGDKTKAFDLVQELLEEFLQSGAKEILEKAQLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-44 46
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-44 46