Gene Information

Name : HP1480 (HP1480)
Accession : NP_208271.1
Strain : Helicobacter pylori 26695
Genome accession: NC_000915
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1554200 - 1555447 bp
Length : 1248 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATTGATAGAAAACTTTTATTGCAAGATTTTGACAAGGTGGCTCTTTCTTTAAAAAAGCGTAATAATGCGATGGATGA
TGAATTAGAGCGTTTGCGCGAAGTCATCACGCATTATAAAAAGCGACTCATTGAATTAGAAGGCTTGCAAGCCTTTCAAA
ACAAGGTTTCTAAAGAATTTGGTATTAAGATGGCTCAAAAAGTGGATACAAGCGATCTCAAAAAAGAGCTAGAAAACAAT
AAAATCAAATTGAATGAGCTTTCCAAAAGCGTGGGCGAATTGGAGCAACAAATTGATTTGAAGCTTTCCATAATCCCCAA
TCTAGTGGATGAAAAAACCCCTTTAGGCACGAATGAAGAAGACAACATAGAAATTAAAAAAATCTTAACCCCAAGGGTTT
TCACTTTCAAACCCAAAGAGCATTTTGAACTCGCTCAACAAAACGGCTGGATTGATTTTGAAAGCGGCGTGAAACTCGCC
AAAAGCCGTTTTTCGGTCATCAGGGGTTTTGGGGCTAAAATTTATCGCGCGCTCATTCATTTAATGCTGGATTTTAATGA
AAAAAATGGCTTTGAAATCATCTACACGCCGGCGTTAGTGAATGAAAAAATGCTTTTTGGGACCGGGCAATTACCCAAAT
TCAAAGAAGATGTTTTCAAAATAGAAAATGAAAATTTGTATCTGATCCCCACCGCTGAAGTAACGCTCACTAATCTCTAC
AACGACACGATCATTAGCGTTGAAAACCTCCCCATTAAAATGACCGCGCACACGCCTTGTTTCAGGAGCGAAGCAGGGAG
CGCGGGCAAGGACACAAGGGGGATGATAAGACAGCACCAATTTGATAAAGTAGAATTAGTGGCTATCACGCACCCTAAAG
AAAGCGATGTTATGCAAGAGCATATGCTAGAGAGCGCGAGCGAAATTTTAAAGGCTTTGGAATTGCCGCACCGGTTTGTG
CAATTGTGCAGTGGGGATTTAGGTTTTAGCGCAAGCAACACGATAGATATTGAAGTGTGGCTGCCCGGGCAAAATTGCTA
CAGAGAAATCAGCTCGGTGTCCAACACGAGGGATTTTCAAGCCAGGCGCGCCAAAATCCGCTTCAAAGAAAATCAAAAAA
ACCAATTAGCGCACACCTTAAACGGCTCTTCTTTGGCGGTAGGCAGGACGATGGTCGCTTTAATGGAAAACCACCAGCAA
GCGGATGGGAGCATCCACATTCCTAAGGCATTAGAAAAATACCTTTAA

Protein sequence :
MIDRKLLLQDFDKVALSLKKRNNAMDDELERLREVITHYKKRLIELEGLQAFQNKVSKEFGIKMAQKVDTSDLKKELENN
KIKLNELSKSVGELEQQIDLKLSIIPNLVDEKTPLGTNEEDNIEIKKILTPRVFTFKPKEHFELAQQNGWIDFESGVKLA
KSRFSVIRGFGAKIYRALIHLMLDFNEKNGFEIIYTPALVNEKMLFGTGQLPKFKEDVFKIENENLYLIPTAEVTLTNLY
NDTIISVENLPIKMTAHTPCFRSEAGSAGKDTRGMIRQHQFDKVELVAITHPKESDVMQEHMLESASEILKALELPHRFV
QLCSGDLGFSASNTIDIEVWLPGQNCYREISSVSNTRDFQARRAKIRFKENQKNQLAHTLNGSSLAVGRTMVALMENHQQ
ADGSIHIPKALEKYL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-77 46