Gene Information

Name : HP1088 (HP1088)
Accession : NP_207879.1
Strain : Helicobacter pylori 26695
Genome accession: NC_000915
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1146594 - 1148519 bp
Length : 1926 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGCGATTGAGTAACGCTGACTTAGAACGATTAAAAAGCATGGCGAATGCACTTCGCTTTTTGTGTGCGGACATGATAGA
TAAGGCTAATAGCGGGCATCCGGGCGTGTGCTTGGGATTAGCTGATGTGATGGTGGTTTTAAGCTTGCACCTAAACCTAA
ACCCCACTAACCCTAAATGGCTCAATAGGGATAGGCTGGTTTTTAGCGGAGGGCATGCGAGCGCGTTAGCGTATAGTTTG
TTGCATTTGTGGGGCTTTGATTTGAGTTTAGAAGATTTAAAGCGTTTCAGGCAATTACACTCTAAAACCCCAGGACACCC
CGAATTGCACCACACCGAAGGCATTGAGATCACCACAGGTCCTTTGGGGCAAGGTTTTGCTAACGCTGTGGGCTTTAGCA
TGGCGAGCCAATACGCTCAAAACCTTTTGGATAAAGAAGCCATTTCTCATAAAGTCTATTGCTTGTGTGGGGATGGGGAT
TTGCAAGAAGGCATTAGTTATGAGAGCGCTTCTTTAGCCGGGCACCTTCGCCTTGATAACCTCATTGTGATTTACGACAG
CAACCAGATCAGCATTGAAGGCGCTATCAATATTAGTTTTAGCGAACAGGTTAAAACGCGGTTTGTGGCGCAAAATTGGG
AAGTGCTAGAATGCGATGGGCATGACTATCAAGCGATTCATAACGCTTTAGAAGAAGCCAAAAAATCCACCAAACCCACG
CTTTTAATCGCTCATACGATTATTGGTAAGGGGGCTGTTGGCTTAGAGGGGAGTGAAAAAACGCATGGCTCGCCTTTAAA
TAAAGAAGTGTTAAAACAATCCAAAGAAAACGCTCAAATCAATCCTAACGAAAGCTTTATCATTAGCCCAAAAAACAAAA
TGCATTTTGAAGAAGTGAAAGTTAGGGGCGTTAGTTTAGAAGCCTTATGGGAAAAATCCTTAAGCCCTAAAATAAAAGAA
AAGATCCATGCGTTAAAGGATTTTGATTTTAGCGCCATCCATTACCCCACCTTTAAAAAAGGCGAATCTCTAGCCACGAG
AGTGAGTAACGGCATGATTTTAAACGCTATCGCTAAAGAATGCGAGGGCTTTTTAGGGGGGAGCGCGGATCTAGCCCCCT
CTAACAACACGCAGTTAAAACACTCTGGCGATTTCCCTTTAGGGCAAAACTTGCATTTTGGGATCAGAGAGCATGCCATG
GGGGCTATCACTAACGCTTTAGCGGCGTATGGCTTGTTTGTGCCTTTTTGCGCGACCTTTTTTGTGTTTAGCGATTACTT
GATGCCCAGCATTCGTTTGAGCGCTTTAATGAAACTGAAAGCCCTTTTTATCTTCACGCATGACAGCATTGGCGTGGGTG
AAGATGGAGCGACGCACCAGCCCATAGAGCAATTGAACCATTTACGCGCTTTGCCCAATTTCTATGCTTTCAGACCCAGC
GACGCTTTTGAAAATACGGCTTGCATGCAAATAGCGTTAAGTTTGAACGCTCCTAGTGGGCTTATTTTATCACGCCAGAA
TTTACCCGTGCTTGATGAGGTTTCTAAAGAGCGGGTTTTAAAAGGGGCGTATGTTAAACACCATTCTAAAGATCCCATTA
TCACGCTTGTTGCGAGCGGGAGCGAAGTGTCTTTGGCTTTAGAGAGCGCTAAAATTTTAGAGCGAGAAAATATCCAAACG
CAAGTCATCAGCGCGCCATGCTTTGACTTGTTGATAGAGCAAGATGAAAGCTATCTTAAAGAACTTTTTAAGGGTAAAGT
CTTAGTCATTGAAGCGAGCCGCGCGATAGAGTGGTATCGTTTTGCGGATAAAATCATTGGCATGGATTCTTTTGGGAGCT
CAGCAAAGGGCGATAAACTCTTTGAAAAATTTGGCTTTAGCGTTGAAAACATTACCGCTCAAGCGAAAAGATTACTCAAC
GCATGA

Protein sequence :
MRLSNADLERLKSMANALRFLCADMIDKANSGHPGVCLGLADVMVVLSLHLNLNPTNPKWLNRDRLVFSGGHASALAYSL
LHLWGFDLSLEDLKRFRQLHSKTPGHPELHHTEGIEITTGPLGQGFANAVGFSMASQYAQNLLDKEAISHKVYCLCGDGD
LQEGISYESASLAGHLRLDNLIVIYDSNQISIEGAINISFSEQVKTRFVAQNWEVLECDGHDYQAIHNALEEAKKSTKPT
LLIAHTIIGKGAVGLEGSEKTHGSPLNKEVLKQSKENAQINPNESFIISPKNKMHFEEVKVRGVSLEALWEKSLSPKIKE
KIHALKDFDFSAIHYPTFKKGESLATRVSNGMILNAIAKECEGFLGGSADLAPSNNTQLKHSGDFPLGQNLHFGIREHAM
GAITNALAAYGLFVPFCATFFVFSDYLMPSIRLSALMKLKALFIFTHDSIGVGEDGATHQPIEQLNHLRALPNFYAFRPS
DAFENTACMQIALSLNAPSGLILSRQNLPVLDEVSKERVLKGAYVKHHSKDPIITLVASGSEVSLALESAKILERENIQT
QVISAPCFDLLIEQDESYLKELFKGKVLVIEASRAIEWYRFADKIIGMDSFGSSAKGDKLFEKFGFSVENITAQAKRLLN
A

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 1e-98 42
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 1e-87 41