Gene Information

Name : pepA (b4260)
Accession : NP_418681.1
Strain : Escherichia coli K12
Genome accession: NC_000913
Putative virulence/resistance : Unknown
Product : multifunctional aminopeptidase A: a cyteinylglycinase, transcription regulator and site-specific recombination factor
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0260
EC number : 3.4.11.1
Position : 4484440 - 4485951 bp
Length : 1512 bp
Strand : -
Note : aminopeptidase A/I

DNA sequence :
ATGGAGTTTAGTGTAAAAAGCGGTAGCCCGGAGAAACAGCGGAGTGCCTGCATCGTCGTGGGCGTCTTCGAACCACGTCG
CCTTTCTCCGATTGCAGAACAGCTCGATAAAATCAGCGATGGGTACATCAGCGCCCTGCTACGTCGGGGCGAACTGGAAG
GAAAACCGGGGCAGACATTGTTGCTGCACCATGTTCCGAATGTACTTTCCGAGCGAATTCTCCTTATTGGTTGCGGCAAA
GAACGTGAGCTGGATGAGCGTCAGTACAAGCAGGTTATTCAGAAAACCATTAATACGCTGAATGATACTGGCTCAATGGA
AGCGGTCTGCTTTCTGACTGAGCTGCACGTTAAAGGCCGTAACAACTACTGGAAAGTGCGTCAGGCTGTCGAGACGGCAA
AAGAGACGCTCTACAGTTTCGATCAGCTGAAAACGAACAAGAGCGAACCGCGTCGTCCGCTGCGTAAGATGGTGTTCAAC
GTGCCGACCCGCCGTGAACTGACCAGCGGTGAGCGCGCGATCCAGCACGGTCTGGCGATTGCCGCCGGGATTAAAGCAGC
AAAAGATCTCGGCAATATGCCGCCGAATATCTGTAACGCCGCTTACCTCGCTTCACAAGCGCGCCAGCTGGCTGACAGCT
ACAGCAAGAATGTCATCACCCGCGTTATCGGCGAACAGCAGATGAAAGAGCTGGGGATGCATTCCTATCTGGCGGTCGGT
CAGGGTTCGCAAAACGAATCGCTGATGTCGGTGATTGAGTACAAAGGCAACGCGTCGGAAGATGCACGCCCAATCGTGCT
GGTGGGTAAAGGTTTAACCTTCGACTCCGGCGGTATCTCGATCAAGCCTTCAGAAGGCATGGATGAGATGAAGTACGATA
TGTGCGGTGCGGCAGCGGTTTACGGCGTGATGCGGATGGTCGCGGAGCTACAACTGCCGATTAACGTTATCGGCGTGTTG
GCAGGCTGCGAAAACATGCCTGGCGGACGAGCCTATCGTCCGGGCGATGTGTTAACCACCATGTCCGGTCAAACCGTTGA
AGTGCTGAACACCGACGCTGAAGGCCGCCTGGTACTGTGCGACGTGTTAACTTACGTTGAGCGTTTTGAGCCGGAAGCGG
TGATTGACGTGGCGACGCTGACCGGTGCCTGCGTGATCGCGCTGGGTCATCATATTACTGGTCTGATGGCGAACCATAAT
CCGCTGGCCCATGAACTGATTGCCGCGTCTGAACAATCCGGTGACCGCGCATGGCGCTTACCGCTGGGTGACGAGTATCA
GGAACAACTGGAGTCCAATTTTGCCGATATGGCGAACATTGGCGGTCGTCCTGGTGGGGCGATTACCGCAGGTTGCTTCC
TGTCACGCTTTACCCGTAAGTACAACTGGGCGCACCTGGATATCGCCGGTACCGCCTGGCGTTCTGGTAAAGCAAAAGGC
GCCACCGGTCGTCCGGTAGCGTTGCTGGCACAGTTCCTGTTAAACCGCGCTGGGTTTAACGGCGAAGAGTAA

Protein sequence :
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGK
ERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFN
VPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVG
QGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVL
AGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHN
PLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKG
ATGRPVALLAQFLLNRAGFNGEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00295 YP_008207760.1 Leucyl aminopeptidase Not tested AbaR25 Protein 2e-90 55
BJAB0868_00299 YP_008211625.1 Leucyl aminopeptidase Not tested AbaR26 Protein 2e-90 55