Gene Information

Name : serS (MPN005)
Accession : NP_109693.1
Strain : Mycoplasma pneumoniae M129
Genome accession: NC_000912
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 7312 - 8574 bp
Length : 1263 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTGGATCGAAACAAATTACGCAATAACCTTGACTTCTTTAAAAAGAAGTTAGTTGAACGGGGTGTAAGTGAAAGCCA
GTTCGAGGCGTACGTGCAAGCTGATAAAGCAATGCGCAAACTGTTGCACCAAATTGAACTGGCCAACCAAAAGCAAACCC
TGTTAGCGCAACAGGTTGCCAAGAAGAAGGGTGATCCGAAGTTATTAAAGGAATCCAAGGAGTTAAAGCAAAAACTAGAA
CAGCTCAACATCGCTTTTAAGGAAGCGGAAACCTTAAGCCAAGAGTTACTGTTAAACCTCCCTAACATTGCTGATGAATC
AGTACCAGTTGGACGGGATGAAACTGCTAACTTAGAACTGCTCAAAGAAGGGCGTAAACCGGTGTTTGACTTTACTCCCT
TACCCCACTGGGAGTTGTGTGAACGCTTACAGTTAGTTGCCTTTGATAAGGCCACTAAGCTAACGGGTGCACGGTTTGTC
GCTTACACTGATAAAGCAGCGAAACTGCTCCGCGCCATTGCTAGCTTAATGATTGACCTCAACAAAAACAAATACCAGGA
GTGAAACGTGCCGGTCATTGTGAACGAGACTAGTCTTACTGGTACGGGTCAGCTACCCAAATTTAAGGATGATGTCTTTA
AGTTAGAAAACACGCGTTACTACCTCTCCCCGACCCTAGAGGTGCAACTAGCCAACCTCCATGCCAACGAAATCTTCACG
GAGGGTGAACTCCCCAAATACTATACCGCTACTGGGGTGAACTTTCGCCAGGAAGCGGGCAGTGCTGGTAAACAAACTAA
GGGTACGATTCGCCTACACCAGTTCCAAAAGGTAGAACTAGTGAAGTTTTGTAAACCAAGTGAAGCGATTCACGAACTGG
AAGAAATGACCCGGGACGCTGAGCAAATTTTGTTAGAACTCAAAATTCCCTTTCGCCGTTTGTTACTCTGTAGCGGTGAC
ATGGGTTTTAGTGCCCAGAAAACCTATGACTTGGAAGTGTGGATGGCGGGTTGCAATGAGTACCGCGAAGTTTCGTCCTG
TTCTTCTTGTGGTGACTTTCAAGCACGCAGAGCAATGATCCGCTATAAGGACTTAACCACAGGCAAGAATACCTATGTGG
CTACCTTAAACGGCACCGCTTTAGCGATTGACCGCATCTTTGCAGCCATCTTGGAACACTACCAAACGAAGGCAGGGGAA
GTAATGATTCCCCAAGCCTTGTTGAAATACTTAGACTTTGACAAAATTACCAAACCAAAATAA

Protein sequence :
MLDRNKLRNNLDFFKKKLVERGVSESQFEAYVQADKAMRKLLHQIELANQKQTLLAQQVAKKKGDPKLLKESKELKQKLE
QLNIAFKEAETLSQELLLNLPNIADESVPVGRDETANLELLKEGRKPVFDFTPLPHWELCERLQLVAFDKATKLTGARFV
AYTDKAAKLLRAIASLMIDLNKNKYQEWNVPVIVNETSLTGTGQLPKFKDDVFKLENTRYYLSPTLEVQLANLHANEIFT
EGELPKYYTATGVNFRQEAGSAGKQTKGTIRLHQFQKVELVKFCKPSEAIHELEEMTRDAEQILLELKIPFRRLLLCSGD
MGFSAQKTYDLEVWMAGCNEYREVSSCSSCGDFQARRAMIRYKDLTTGKNTYVATLNGTALAIDRIFAAILEHYQTKAGE
VMIPQALLKYLDFDKITKPK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 4e-81 45