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Name : leuS (MPN384) Accession : NP_110072.1 Strain : Mycoplasma pneumoniae M129 Genome accession: NC_000912 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 460381 - 462762 bp Length : 2382 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGTATAACCACAACTTACTGGAAGAGAAATGGTTGCAATTGTGAAAAACGAAGCAAGTTAACCGTTTTTTTGATGATAA AACTAAGCCCAAATACTATATCTTGGACATGTTCCCTTATCCTTCAGCGGCTGGTTTACACCTGGGACATGTGCGCGCTT ACACCATTACCGATGTTTTGAGTCGTTATCATAAAGCGAAGGGTTTTAATGTGATTCACCCGATTGGCTTTGATGCTTTT GGGTTACCAGCAGAACAATACGCGATTGCCTCCAATAAGCATCCTGGTGACTGAACTGACAAAAACATTACTAATTTCAT TGAGCAGTTAACGGCCTTTGGCTTTGATTATGACTACCAGCTGTCTTTAAAGACAACTGATCCACGCTATTACCAGTACA CACAGTGGATCTTTGGTCAGTTATTTGAAGCCGGTTTGGCTGAAGTGAAGGAGATTGATGTCAACTGGTGTGCTGAATTG GGCACCGTTTTAGCCAACGAAGAGGTGTTGATTGACAGTAATGGTAATGCGGTGAGTGAGCGTGGCGAGTTCCCGGTAAC CAAGCGAAAAATGAAGCAATGGGTGTTGAAAATAACTGCTTTTGCTGAAAGTTTACTCAATGGTTTGGCTGAGCTGGATT GACATCAATCTATTAAGGAAATGCAAACCAACTGGATTGGTAAAAGTGAAGGGGTAGAGGTAACGTTTGACATAGAAAAC TCCAAGGAAACGATTACCATTTTTACCACTAAGGTGCAAACTATTTTTGGTGTAACCTTTTTAGCGCTTTCCAATAGCCA TCCCTTAGTAAAAGAGGTAGCTAAAACCAACCCCAAGATAGCACAGTTTCTCCAAAAACAAGCACAGAAAACCACCACTG TAAAGCAACCTGAGACGCTCCATGACGGGGTTGATTTAAAACTTAAAGCAATTAATCCAGCAACTAATACTGCCATTCCG TTGTATGTAGCTAACTATGTAGTGGAAGGTTATGGTACGGATGCTGTGATGGGTGTGCCAGCGCATAACGAAAACGATAA CTTCTTCGCGCGGAAGCAAAAGCTACCGATTATTACCGTCATTGATAAACAGGAACGCTTGCAACACTCCGGGCAGTTTA GCGGGCTCAACTCCCAAACTGCTAACACCCAAATTACGCAAATGTTAGTCGAGCGTCAAAAAGCTAAAAAAACAACGGTG TACAAACTCCGTGACTGGATTTTTAGCCGTCAACGTTACTGGGGTGAACCTTTTCCGATTTTGTTTGACGAAAACAACCA ACCCCATTTAGTTAAAGAGCTCCCCGTTACCCTACCAGCTTTGGCTAACTATCAACCTGATGGTTCGACTAACCCACCAT TGTGACGAAACCAGGAGTGGGCTAAGGTGAAACAAGGCAATCAAACTTTTACTCGGGAAACGAGCACTATGCCCCAGTGG GCTGGTTCTTGTTGGTATTACTTGGGTTATTTGATGTTAATTAATAACGAAAACTTTTGGCCAATTGACTCCAGGGAAGC GAAAGATCTTTTTGAGCGTTACCTACCAGTGGATCTGTATGTGGGTGGTGCCGAACATGCCGTGTTGCACCTCTTGTACG CGCGCTTTTGGCACCAATTCTTGTACCAAAAGGGAATAGTCACCACTAAAGAGCCCTTTAAAAAGTTAATTAACCAGGGC ATGGTATTGGGACCAGATGGCAAAAAGATGTCCAAATCCAAGGGCAACACAATCAACCCTACGCCACTAATTGATTCTCA TGGTGCTGATGCCTTGCGACTTTACTTGATGTTTATGGGGCCGATTAGCGCGGCGTTGACCTGATTGGATGATGGGTTAA ACGGAATGCGGCGTTGACTTGATCGGGTGCACAATTTCTTTCACAAGGAAAACATTATTAAAGAAACGGTAGATCAAGAA ACTGTTTATGGTTATAACCTCTTTTTAAAGCGTAGTTTCGAGCACTTAGAGAAACAAGAACTCAATTTGGTAATTAGCCA AATGATGATCTTTTTAAACCTGCTTTACAAAACAAAACAATTAACCCTGGCTTATGCAAAGGGCTTTTTGACGGTGTTAT CGTTTTTTGCACCTTATTTAGCGGAAGAATTAAACGCTAAACTAGGGATGGAGCCGTTTATTGTTCATGCTCAACTACCA AATGTTGATAACAGCGTACTTGAAACCGATAAGGTTAAAATTATTCTTTCGGTCAACGGTCGCTTCAAAGGTACCAAGGA ATTTGCTAAAGGGGTTGATGAACAGACTGTCTTAAAAGCCTTTAAGACAGATCCGGAATTCCAAGCGTTGTTCGACCAAC CCTTAGCGCGTGTTGTTTTTGTCCCTAATCGTATTATTAATGTTCTTTTAAAATCCGAATAG Protein sequence : MYNHNLLEEKWLQLWKTKQVNRFFDDKTKPKYYILDMFPYPSAAGLHLGHVRAYTITDVLSRYHKAKGFNVIHPIGFDAF GLPAEQYAIASNKHPGDWTDKNITNFIEQLTAFGFDYDYQLSLKTTDPRYYQYTQWIFGQLFEAGLAEVKEIDVNWCAEL GTVLANEEVLIDSNGNAVSERGEFPVTKRKMKQWVLKITAFAESLLNGLAELDWHQSIKEMQTNWIGKSEGVEVTFDIEN SKETITIFTTKVQTIFGVTFLALSNSHPLVKEVAKTNPKIAQFLQKQAQKTTTVKQPETLHDGVDLKLKAINPATNTAIP LYVANYVVEGYGTDAVMGVPAHNENDNFFARKQKLPIITVIDKQERLQHSGQFSGLNSQTANTQITQMLVERQKAKKTTV YKLRDWIFSRQRYWGEPFPILFDENNQPHLVKELPVTLPALANYQPDGSTNPPLWRNQEWAKVKQGNQTFTRETSTMPQW AGSCWYYLGYLMLINNENFWPIDSREAKDLFERYLPVDLYVGGAEHAVLHLLYARFWHQFLYQKGIVTTKEPFKKLINQG MVLGPDGKKMSKSKGNTINPTPLIDSHGADALRLYLMFMGPISAALTWLDDGLNGMRRWLDRVHNFFHKENIIKETVDQE TVYGYNLFLKRSFEHLEKQELNLVISQMMIFLNLLYKTKQLTLAYAKGFLTVLSFFAPYLAEELNAKLGMEPFIVHAQLP NVDNSVLETDKVKIILSVNGRFKGTKEFAKGVDEQTVLKAFKTDPEFQALFDQPLARVVFVPNRIINVLLKSE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 1e-150 | 41 |
