Gene Information

Name : nrdE (MPN324)
Accession : NP_110012.1
Strain : Mycoplasma pneumoniae M129
Genome accession: NC_000912
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 383525 - 385690 bp
Length : 2166 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGTCAGTTAAAGAAAAGATTCCTGCTTTCAACACCCAAGAAGACTTAGAAAGCTATATTTCCTTAAATGCCTACACTAA
GGTGTACGGTGATTTTAAGATGGATTTACACGCTGTGGAGGCTTACATCCAAGAGCATGTCAAACCCAAAACAAAGGTGT
TTCACTCCACCAAGGAACGCTTAGACTTTCTAGTAAAGAATGATTATTACGATGAGAACATCATCAACATGTACAGCTTT
GAGCAGTTTGAGGAAATTACACGTAAGGCTTACGCTTACCGTTTTCGTTATGCTAACTTTATGGGGGCATTTAAGTTTTA
CAACGCTTATGCACTGAAAACCTTTGATGGGAAGTGGTATTTAGAAAACTATGAAGACCGCGTTGTCATGAACGTGCTCT
TTTTAGCCAATGGTAACTATAACAAGGCTTTAAAGTTACTCAAACAAATTATTACCAACCGCTTTCAACCAGCTACCCCA
ACTTTTTTAAATGCGGGACGAAAAAAACGTGGTGAGTTTGTGTCGTGTTACTTACTGCGCATAGAAGACAACATGGAATC
AATTGGTCGTGCCATTACCACTACCCTACAGCTCTCCAAGCGTGATGGTGGGGTGGCGTTATTGCTCACTAACATCCGCG
AATCGGGTGCGCCAATTAAAAAAATAGAAAACCAGTCATCAGGCATTATTCCAATTATGAAGCTGTTGGAAGACTCTTTT
TCTTACGCCAACCAATTAGGGCAAAGACAGGGAGCAGGAGCAGTGTATCTCCATGCCCACCACCCCGATGTCATGCAGTT
TTTAGACACAAAGCGCGAAAACGCTGATGAAAAGATCCGGATTAAGTCGCTGTCTTTGGGTCTAGTTATTCCCGACATTA
CCTTTACTTTAGCTAAAAACAATGAGGAGATGGCCTTGTTTAGTCCGTATGATGTGTATGAGGAGTATGGCAAACCCTTG
TCAGACATTTCAGTCACGGAAATGTATTACGAACTGTTAGCGAACCAACGCATTAAAAAGACCTTTATTAATGCGCGCAA
GTTCTTCCAAACAGTGGCGGAACTGCACTTTGAAAGCGGTTATCCTTACATCTTATTTGACGATACGGTTAACCGGCGCA
ACGCGCACCCCAACCGCATTGTCATGTCTAACCTCTGTAGTGAAATTGTCCAACCCTCCACTCCATCGGAGTTCCACCAC
GATTTGGCTTTTAAAAAGGTTGGTAATGACATTAGCTGTAACTTGGGTAGCTTAAACATTGCCAAAGCAATGGAAAGCGG
ACCGGAGTTCTCGGAGTTGGTTAAACTAGCGATCGAATCACTTGATTTAGTTTCAAGGGTAAGCAATTTAGAAACGGCTC
CATCGATCCAAAAGGGTAATTCCGAAAATCATGCTTTGGGATTAGGGGCAATGAACTTGCACGGTTTTTTAGCAACTAAC
CAAATTTATTACAACTCCCCTGAAGCAATCGACTTTACTAACATCTTTTTCTATACGGTAGCTTACCATGCCTTTAAAGC
ATCCAGTGAGCTAGCTTTAGAGAAGGGTAAGTTTAAAAACTTTGAAAACACCAAGTTTGCTGATGGGAGCTACTTTGATA
AATATATCAAAGTAGAACCAGACTTTTGAACACCCAAAACCGAGCGCGTTAAGGCGTTGTTTCAAAAGTACCAAGTGGAA
ATACCAACACGTGAAAACTGAAAGGAGTTAGCACTCAACATTCAGAAAAACGGTTTGGCCAATTCCCACTTACTGGCAAT
TGCTCCAACGGGTTCAATTTCCTATCTCTCCTCCTGTACTCCTTCACTCCAACCGGTAGTATCCCCGGTAGAAGTGCGCA
AGGAAGGTCGGTTGGGACGGATTTATGTACCGGCTTACCAACTCAATAAAGACAGTTACCCTTTTTATAAAGATGGTGCT
TACGAACTGGGTCCCGAACCAATTATTAACATAGCAGCAGCGGCACAACAACACGTCGATCAAGCGATTTCGCTCACCCT
ATTTATGACTGATAAGGCTACCACTCGTGACCTCAATAAAGCTTATATTTATGCTTTTAAAAAGGGTTGTTCTTCCATTT
ACTATGTCCGAGTGCGCCAGGAAGTACTAGAGGACAGTGAGGATCACACCATTCAAATGCAGCAGTGTGAGGCCTGTGTG
ATTTAA

Protein sequence :
MSVKEKIPAFNTQEDLESYISLNAYTKVYGDFKMDLHAVEAYIQEHVKPKTKVFHSTKERLDFLVKNDYYDENIINMYSF
EQFEEITRKAYAYRFRYANFMGAFKFYNAYALKTFDGKWYLENYEDRVVMNVLFLANGNYNKALKLLKQIITNRFQPATP
TFLNAGRKKRGEFVSCYLLRIEDNMESIGRAITTTLQLSKRDGGVALLLTNIRESGAPIKKIENQSSGIIPIMKLLEDSF
SYANQLGQRQGAGAVYLHAHHPDVMQFLDTKRENADEKIRIKSLSLGLVIPDITFTLAKNNEEMALFSPYDVYEEYGKPL
SDISVTEMYYELLANQRIKKTFINARKFFQTVAELHFESGYPYILFDDTVNRRNAHPNRIVMSNLCSEIVQPSTPSEFHH
DLAFKKVGNDISCNLGSLNIAKAMESGPEFSELVKLAIESLDLVSRVSNLETAPSIQKGNSENHALGLGAMNLHGFLATN
QIYYNSPEAIDFTNIFFYTVAYHAFKASSELALEKGKFKNFENTKFADGSYFDKYIKVEPDFWTPKTERVKALFQKYQVE
IPTRENWKELALNIQKNGLANSHLLAIAPTGSISYLSSCTPSLQPVVSPVEVRKEGRLGRIYVPAYQLNKDSYPFYKDGA
YELGPEPIINIAAAAQQHVDQAISLTLFMTDKATTRDLNKAYIYAFKKGCSSIYYVRVRQEVLEDSEDHTIQMQQCEACV
I

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 0.0 55