Gene Information

Name : nrdF (MPN322)
Accession : NP_110010.1
Strain : Mycoplasma pneumoniae M129
Genome accession: NC_000912
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 382018 - 383037 bp
Length : 1020 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGGCTAACACAAAAAAATACTTTTTAGAATCAGTTTCTCCCTTAGAATATGCACAAAAAAAGTTTCAGGGCAACTTGCG
CTCGGTTAACTGAAACCTAGTGGATGATGAGAAGGATCTGGAAGTGTGAAACCGGATCACGCAAAACTTCTGGTTACCAG
AAAAGATTCCGGTATCCAATGACATTCCATCATGAAAGCAGCTGTCTAAGGAATGGCAGGATTTAATTACCAAAACCTTT
ACGGGGTTAACATTACTTGACACCATCCAAGCTACCATTGGTGACATTAAGCAAATTGACTATGCTTTAACAGATCACGA
GCAGGTAATTTACGCCAACTTTGCCTTTATGGTGGGGGTACACGCGCGCTCTTATGGCACCATCTTTTCCACTCTGTGTA
CTTCAGAACAAATTACTGAAGCACATGAATGGGTGGTGAAAACCGAAAGCTTGCAAAAGCGCGCTAAGGCTTTAATTCCC
TATTACACCGGGAAAGACCCATTAAAGTCTAAGGTAGCAGCCGCTTTAATGCCCGGGTTCTTACTGTATGGTGGGTTTTA
TTTACCGTTTTACCTCTCCTCGCGTAAACAGCTACCCAACACTTCGGACATTATTCGCTTAATTTTGCGCGATAAGGTAA
TCCATAACTATTACAGTGGGTATAAGTTCCAGCGTAAAGTGGAAAAGATGTCCAAGGAAAAACAGGCTGAGATGAAACGG
TTTGTCTTTGATTTAATGTACGAACTGATTGAGTTGGAAAAGGCATACCTCAAGGAACTGTATGAAGGGTTTGGGATTGT
AGAAGATGCCATTAAATTCAGTATTTATAACGCTGGTAAGTTTTTGCAAAACTTAGGGTATGACTCACCGTTTACAGAAG
AAGAAACGCGGATTAAACCAGAAATTTTTGCCCAATTGTCAGCCAGAGCCGATGAAAACCACGATTTCTTTTCTGGTAAT
GGTTCGTCATATGTGATGGGAATTAGTGAAGAGACCGAAGATAAGGATTGAGACTTTTAA

Protein sequence :
MANTKKYFLESVSPLEYAQKKFQGNLRSVNWNLVDDEKDLEVWNRITQNFWLPEKIPVSNDIPSWKQLSKEWQDLITKTF
TGLTLLDTIQATIGDIKQIDYALTDHEQVIYANFAFMVGVHARSYGTIFSTLCTSEQITEAHEWVVKTESLQKRAKALIP
YYTGKDPLKSKVAAALMPGFLLYGGFYLPFYLSSRKQLPNTSDIIRLILRDKVIHNYYSGYKFQRKVEKMSKEKQAEMKR
FVFDLMYELIELEKAYLKELYEGFGIVEDAIKFSIYNAGKFLQNLGYDSPFTEEETRIKPEIFAQLSARADENHDFFSGN
GSSYVMGISEETEDKDWDF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 3e-64 51