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Name : thyA (MPN320) Accession : NP_110008.2 Strain : Mycoplasma pneumoniae M129 Genome accession: NC_000912 Putative virulence/resistance : Unknown Product : thymidylate synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0207 EC number : 2.1.1.45 Position : 380664 - 381527 bp Length : 864 bp Strand : + Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived DNA sequence : ATGCAGCAGTATCTAGATTTAGCCCGTTATGTTTTAGAGCACGGAAAATACCGTCCAAATCGCACTGATACTGCTGGCAT TGGTGTCTTTGGTTACCAGATGCACTTTGATATTTCAAAACACTTTCCGCTCTTGACTACGAAGAAGGTGCACTGAAAGT CGATTGTGCACGAACTTTTGTGGTTCATTAAGGGTGACACCAATATTAAGTACCTAGTCGACAATAAGGTCAACATTTGG AATGAATGACCTTACGAAAGCTTTAAAAAGTCACCTCACTTTAACGGTGAGAGTCAAAAGGAGTTCATTGAACGGATTCG ACAAGACGCGAAGTTTGCCCAACAGTTTGGTAACCTCGGACCCGTTTATGGAAAGCAATGGCGTGACTTTAACGGAGTCG ATCAATTGAAAAAGGTAATTGCGCAAATTAAGGTAAATCCGTTTTCGCGGCGCTTAATTGTGTCTAGTTGAAATCCCAAT GAGGTGGATCAAATGTTGCTCCCGCCTTGTCATTCACTGTACCAGTTTTACGTACAGGACGGGCAGTTGAGCTGCCAGTT GTACCAGCGCAGTGGTGATATTTTTCTAGGTATCCCCTTCAACATTGCGTCCTACTCTCTTCTGGTGTACTTAGTTGCTA AGGAAACTAACCTAAAACCAGGGAGCTTTGTCCACACCATTGGCGATGCCCACATTTACGAAAATCACTTGGAACAAATT AAGTTGCAATTAACACGTCAACCCAAACCATTGCCCAAGGTAGTTTTAAAGAGTGATAAATCAATTTTTGATTATCAATT CGATGATATTGAACTGGTGGATTACGACCACCACCCTACAATTAAAGGAGAGGTAGCAGTTTAA Protein sequence : MQQYLDLARYVLEHGKYRPNRTDTAGIGVFGYQMHFDISKHFPLLTTKKVHWKSIVHELLWFIKGDTNIKYLVDNKVNIW NEWPYESFKKSPHFNGESQKEFIERIRQDAKFAQQFGNLGPVYGKQWRDFNGVDQLKKVIAQIKVNPFSRRLIVSSWNPN EVDQMLLPPCHSLYQFYVQDGQLSCQLYQRSGDIFLGIPFNIASYSLLVYLVAKETNLKPGSFVHTIGDAHIYENHLEQI KLQLTRQPKPLPKVVLKSDKSIFDYQFDDIELVDYDHHPTIKGEVAV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| thyA | YP_189147.1 | thymidylate synthase | Not tested | ¥ÕSP¥â | Protein | 1e-76 | 53 |
| thyA | YP_001800914.1 | thymidylate synthase | Not tested | Not named | Protein | 3e-62 | 48 |
