Gene Information

Name : guaA (slr0213)
Accession : NP_442140.1
Strain : Synechocystis sp. PCC 6803
Genome accession: NC_000911
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2504415 - 2506043 bp
Length : 1629 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGACTACCCAAATCCCCGTTCCCCCCGTTGTAAGCGACCAGGCTCTGCCGGACCGCATATCCGATCGCCTCAAGGGGCA
GATCATCGTTATTTTAGACTTTGGCTCCCAGTATTCGGAACTAATTGCCCGACGCATCCGGGAAACTGAAGTTTATTCCG
AAGTTTTGTCCTACCGCACCACGGCGCAACAGTTGCGGGAAATTAAGCCCAAAGGCATTATCCTTTCCGGTGGCCCCAAT
TCCGTTTACGACCAGGGGGCTCCCGAGTGTGACCCAGAAATTTTTCAGTTAGGCGTTCCTGTGTTGGGAGTCTGCTATGG
CATGCAACTGATGGTTAAACAGTTGGGCGGCCGGGTGGAGCGGGCCAAGCGGGGGGAATATGGCAAAGCGAGTCTGCACA
TCGACGACCCCACTGATTTGCTCACCAATGTAGAAAACGACAGTACCATGTGGATGAGCCATGGGGATTCCTGTGTGGAT
CTGCCGACGGGCTTTGAAATCCTCGCCCACACGGACAATACTCCCTGTGCAGCGATCGCCGATCATCAAAAGGCTTTGTT
TGGGGTACAGTTTCACCCGGAAGTGGTGCATTCTGTGGGGGGCATTGCCCTCATCCGCAACTTTGTCTATCACATTTGCC
ACTGTGAACCCACTTGGACCACCGCCGCTTTCATTGAAGAATCCATTCGGGAAGTCCGTTCCCAAGTAGGTGATCGCCGA
GTTTTATTAGCCCTTTCCGGTGGGGTAGACTCATCCACTTTGGCTTTTCTGCTCCATCGGGCGATCGGGGATAACCTCAC
CTGTATGTTCATTGACCAAGGTTTCATGCGTAAAGGGGAGCCGGAAAGGTTAGTGGAACTATTTGATCACCAGTTTCATA
TCCCGGTCCAATACGTCAACGCCCGCGACCGTTTCCTCAAGCAACTGGAAGGAGTAACGGACCCAGAGGAAAAACGTCGG
CTGATTGGGCACGAATTTATCCAGGTATTTGAAGAAGAGTCCAACCGTCTTGGGCCCTTTGATTACTTGGCCCAGGGAAC
CCTTTATCCCGACGTAATCGAATCGGCTGATAGTAACGTGGACCCGAAAACCGGCGAACGGGTGGCGGTAAAAATTAAAA
GTCACCACAACGTCGGAGGTTTACCCAAAAATCTCCGCTTTAAACTGGTGGAACCCCTCCGCAAACTATTCAAAGACGAA
GTAAGAAAATTAGGTCGCTCCATTGGTTTACCAGAAGAAATTGTCCGTCGTCATCCTTTCCCTGGCCCTGGCCTAGCCAT
TCGTATCATTGGCGAAGTTACCTCAGAGCGGCTTAATATTTTGCGGGATGCGGACTTCATTGTGCGGGACGAAATTTCCA
AACGGGGTATTTACCATGACTATTGGCAAGCTTTTGCTGTACTGTTACCCATCCGCAGCGTGGGGGTAATGGGGGACAAA
CGCACCTATGCTCACCCCGTTGTTCTACGCTTTATCACCAGTGAAGACGGTATGACCGCCGATTGGGCCCGGGTTCCCTA
CGATATTCTCGAAGCCATTTCCAACCGCATTGTCAACGAAGTTAAGGGGGTTAACCGGGTAGTTTATGACATCACGTCCA
AGCCCCCTGGCACTATCGAGTGGGAATGA

Protein sequence :
MTTQIPVPPVVSDQALPDRISDRLKGQIIVILDFGSQYSELIARRIRETEVYSEVLSYRTTAQQLREIKPKGIILSGGPN
SVYDQGAPECDPEIFQLGVPVLGVCYGMQLMVKQLGGRVERAKRGEYGKASLHIDDPTDLLTNVENDSTMWMSHGDSCVD
LPTGFEILAHTDNTPCAAIADHQKALFGVQFHPEVVHSVGGIALIRNFVYHICHCEPTWTTAAFIEESIREVRSQVGDRR
VLLALSGGVDSSTLAFLLHRAIGDNLTCMFIDQGFMRKGEPERLVELFDHQFHIPVQYVNARDRFLKQLEGVTDPEEKRR
LIGHEFIQVFEEESNRLGPFDYLAQGTLYPDVIESADSNVDPKTGERVAVKIKSHHNVGGLPKNLRFKLVEPLRKLFKDE
VRKLGRSIGLPEEIVRRHPFPGPGLAIRIIGEVTSERLNILRDADFIVRDEISKRGIYHDYWQAFAVLLPIRSVGVMGDK
RTYAHPVVLRFITSEDGMTADWARVPYDILEAISNRIVNEVKGVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-145 55
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-145 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-145 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-129 51