Gene Information

Name : nrdF (MG_229)
Accession : NP_072895.1
Strain : Mycoplasma genitalium G37
Genome accession: NC_000908
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 275141 - 276163 bp
Length : 1023 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGGCAGCTAACAATAAAAAGTACTTTTTAGAATCATTTTCCCCACTTGGGTATGTAAAGAATAATTTTCAGGGCAACTT
ACGTTCTGTAAACTGGAATTTGGTTGATGATGAGAAGGATTTGGAAGTGTGAAACAGGATTGTTCAGAACTTTTGGTTAC
CTGAAAAGATCCCTGTATCCAATGACATCCCCTCATGAAAGAAACTCTCAAAGGATTGACAGGATCTGATCACTAAGACC
TTTACTGGTTTAACACTACTTGATACTATCCAAGCTACCATTGGTGACATCTGTCAAATTGATCATGCTCTAACTGATCA
TGAGCAGGTTATTTATGCAAACTTTGCTTTTATGGTAGGGGTACATGCCCGTTCCTATGGAACGATCTTCTCAACTTTAT
GTACATCAGAACAGATTAACGCTGCTCATGAGTGGGTTGTAAACACTGAAAGTCTCCAGAAAAGAGCAAAGGCATTAATC
CCTTACTATACGGGCAATGACCCGTTAAAATCAAAGGTAGCAGCAGCTTTAATGCCTGGGTTTTTACTGTATGGTGGGTT
TTATTTGCCTTTTTACTTGTCATCAAGAAAACAACTACCAAATACATCTGATATTATCCGCTTAATCCTTCGTGATAAAG
TGATCCATAACTATTACAGTGGTTATAAATACCAACGTAAACTAGAAAAACTCCCTTTAGCAAAACAAAAGGAGATGAAA
GCATTTGTTTTTGAACTAATGTATCGGTTAATTGAACTTGAAAAGGACTATTTAAAAGAGCTTTATGAAGGGTTTGGAAT
TGTTGATGATGCCATTAAGTTCAGTGTTTACAATGCTGGTAAGTTTTTACAGAACTTAGGTTATGACTCCCCGTTTACTG
CAGCAGAAACCAGGATTAAACCAGAGATTTTTGCCCAACTATCAGCACGTGCTGATGAAAACCATGACTTTTTCTCAGGA
AACGGTTCGTCGTATGTGATGGGAGTTAGTGAAGAGACAAATGATGATGATTGGAACTTTTAA

Protein sequence :
MAANNKKYFLESFSPLGYVKNNFQGNLRSVNWNLVDDEKDLEVWNRIVQNFWLPEKIPVSNDIPSWKKLSKDWQDLITKT
FTGLTLLDTIQATIGDICQIDHALTDHEQVIYANFAFMVGVHARSYGTIFSTLCTSEQINAAHEWVVNTESLQKRAKALI
PYYTGNDPLKSKVAAALMPGFLLYGGFYLPFYLSSRKQLPNTSDIIRLILRDKVIHNYYSGYKYQRKLEKLPLAKQKEMK
AFVFELMYRLIELEKDYLKELYEGFGIVDDAIKFSVYNAGKFLQNLGYDSPFTAAETRIKPEIFAQLSARADENHDFFSG
NGSSYVMGVSEETNDDDWNF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 2e-65 51