Gene Information

Name : metB (HI0086)
Accession : NP_438259.1
Strain : Haemophilus influenzae Rd KW20
Genome accession: NC_000907
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 90190 - 91335 bp
Length : 1146 bp
Strand : -
Note : catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity

DNA sequence :
GTGCGGTCAATTTTTTCATTATTTTTAGAGGATGTTATGACACAACAATATGCTATCGATACTTTATTAGCTCAAGCAGG
CAATCGCAGTGATGAGCGTACGGGCGCGGTTTCTGCACCAATTTTTCTTTCTACGGCTTATGGTCATTGTGGTATCGGTG
AAAGTACGGGATTTGATTACACACGTACCAAAAATCCAACTCGCACAGTATTAGAAGAAACGATAGCTAAATTAGAGAAT
GGAGATCGTGGTTTTGCGTTTTCTTCTGGTATGGCTGCAATTCAAGTTTTGATGACGCTTTTTACCGCCCCAGATGAATG
GATTGTTTCTAGCGATGTGTATGGTGGTACTTATCGATTATTAGATTTTTCTTATAAAAATAACAATAGTGTAAAACCTG
TTTATGTTAATACAGCATCTGCTTCAGCAATTGAGGCTGCCATTAACCCAAATACGAAAGCGATTTTTATTGAAACCCCA
TCGAATCCTTTAATGGAAGAATGTGATGTGGTTGAAATTGCAAAACTTGCGAAAAAACATAACTTAATGTTGATCGTGGA
TAATACGTTTTTAACGCCTGTGCTTTCTCGTCCATTAGATTTAGGTGCGGATGTGGTAATTCACAGCGGAACTAAATATA
TTGCTGGGCATAATGATGCACTTGTTGGTTTAATTGTTGCGAAAGGGCAAGAACTTTGTGATCGCATTGCTTATATTCAA
AATGGTGCAGGGGCGGTGCTTTCTCCTTTTGATTCTTGGCTGACTATTCGTGGTATGAAGACCCTTTCTTTGCGTATGAA
ACGCCATCAAGAAAATGCACAAGCTATTGCGGAATTTTTAAAAGCTCAACCACAAGTGGAATCGGTGCTTTATCCGAATA
AAGGTGGGATGTTGTCTTTCCGTTTGCAAGATGAAGCTTGGGTTAATACATTTTTAAAATCCATCAAATTGATTACTTTT
GCAGAAAGTCTAGGCGGCACAGAAAGTTTTATTACTTATCCTGCCACTCAAACTCATATGGATATTCCAGAATCCGAGCG
TGTAGCTCGTGGGATTACTAATACCTTGTTGCGTTTTTCAGTCGGTATTGAAGATGTAGAAGATATTAAAGCGGACTTAT
TACAAGCTTTTGCAAACTTAAAATAA

Protein sequence :
MRSIFSLFLEDVMTQQYAIDTLLAQAGNRSDERTGAVSAPIFLSTAYGHCGIGESTGFDYTRTKNPTRTVLEETIAKLEN
GDRGFAFSSGMAAIQVLMTLFTAPDEWIVSSDVYGGTYRLLDFSYKNNNSVKPVYVNTASASAIEAAINPNTKAIFIETP
SNPLMEECDVVEIAKLAKKHNLMLIVDNTFLTPVLSRPLDLGADVVIHSGTKYIAGHNDALVGLIVAKGQELCDRIAYIQ
NGAGAVLSPFDSWLTIRGMKTLSLRMKRHQENAQAIAEFLKAQPQVESVLYPNKGGMLSFRLQDEAWVNTFLKSIKLITF
AESLGGTESFITYPATQTHMDIPESERVARGITNTLLRFSVGIEDVEDIKADLLQAFANLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-68 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-69 43