Gene Information

Name : kdsB (HI0058)
Accession : NP_438231.1
Strain : Haemophilus influenzae Rd KW20
Genome accession: NC_000907
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 59486 - 60250 bp
Length : 765 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGTCATTTACCGTGATTATCCCCGCTCGTTTTGCATCAAGTCGTTTGCCAGGAAAACCTCTTGCTGATATTAAAGGTAA
GCCAATGATTCAACATGTATTTGAGAAAGCACTGCAGTCTGGGGCGAGCCGAGTGATTATTGCCACCGATAATGAAAATG
TGGCTGATGTTGCCAAAAGTTTTGGTGCTGAAGTCTGTATGACTTCGGTTAATCATAATTCTGGTACAGAACGTTTAGCA
GAAGTTGTAGAAAAATTAGCTATTCCTGACAATGAAATCATTGTCAATATTCAAGGCGATGAGCCTTTGATTCCTCCCGT
TATCGTGCGACAAGTGGCAGATAATTTAGCAAAATTTAATGTCAATATGGCAAGCCTTGCGGTAAAAATTCACGATGCTG
AGGAATTATTTAATCCAAATGCAGTGAAAGTATTAACAGATAAAGATGGCTATGTGCTGTATTTTTCCCGTTCGGTTATT
CCTTATGATCGTGATCAGTTTATGAATTTGCAGGATGTTCAGAAAGTACAGCTTTCTGACGCTTACTTACGTCATATTGG
CATTTACGCATATCGTGCGGGTTTCATAAAACAATATGTGCAATGGGCACCGACTCAACTTGAAAATCTAGAAAAACTTG
AGCAGCTTCGTGTGTTATATAACGGCGAACGTATTCACGTAGAACTTGCGAAAGAAGTGCCTGCAGTGGGGGTGGATACC
GCCGAAGATTTGGAAAAAGTGCGGGCAATTTTAGCGGCGAATTAA

Protein sequence : 
MSFTVIIPARFASSRLPGKPLADIKGKPMIQHVFEKALQSGASRVIIATDNENVADVAKSFGAEVCMTSVNHNSGTERLA
EVVEKLAIPDNEIIVNIQGDEPLIPPVIVRQVADNLAKFNVNMASLAVKIHDAEELFNPNAVKVLTDKDGYVLYFSRSVI
PYDRDQFMNLQDVQKVQLSDAYLRHIGIYAYRAGFIKQYVQWAPTQLENLEKLEQLRVLYNGERIHVELAKEVPAVGVDT
AEDLEKVRAILAAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-39 44
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 3e-39 44
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 1e-39 44