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Name : topB (HI0444) Accession : NP_438605.1 Strain : Haemophilus influenzae Rd KW20 Genome accession: NC_000907 Putative virulence/resistance : Unknown Product : DNA topoisomerase III Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0550 EC number : - Position : 465334 - 467289 bp Length : 1956 bp Strand : + Note : decatenates replicating daughter chromosomes DNA sequence : ATGCGTTTATTTATCGCCGAAAAACCAAGCTTAGCTCGCGCTATTGCTGATGTGCTCCCGAAACCCCATCAACGTGGGGA TGGTTTTATTAAATGCGGCGATAATGATGTGGTAACTTGGTGTGTAGGGCATTTGCTCGAGCAAGCAGAACCCGATGCCT ATGATCCTAAATTCAAACAATGGCGTTTAGAACATCTCCCTATCATTCCTGAAAAATGGCAACTTTTACCGCGAAAAGAA GTAAAAAAACAACTTTCTGTGGTAGAAAAACTGATCCATCAAGCGGATACACTTGTTAATGCAGGAGACCCTGATAGAGA AGGACAATTACTTGTAGATGAAGTGTTCAGTTATGCCAATTTATCTGCCGAAAAACGCGATAAAATTTTACGCTGTTTGA TTAGCGACCTAAATCCAAGTGCGGTAGAAAAAGCGGTTAAAAAATTACAACCCAACCGTAATTTTATTCCTCTTGCCACA TCCGCTCTCGCACGAGCTCGCGCCGATTGGCTTTATGGCATTAATATGACCAGAGCTTATACCATTCGAGGTAGACAAAC TGGCTATGATGGCGTGCTTTCTGTTGGACGAGTGCAAACCCCTGTGCTAGGTTTAATTGTACGTCGAGATTTAGAAATTG AGCATTTCCAGCCCAAAGACTTCTTTGAAGTACAGGCTTGGGTTAATCCAGAGAGCAAAGAAGAAAAAACTCCAGAAAAA TCAACCGCACTTTTCAGTGCCTTATGGCAACCTAGCAAAGCTTGCGAGGATTACCAAGATGATGACGGCAGGGTGCTCTC TAAAGGATTAGCAGAAAAAGTTGTAAAACGTATTACAAATCAACCTGCAGAAGTCACCGAATACAAAGACGTTCGTGAAA AAGAAACGGCGCCCTTGCCTTATTCACTTTCTGCGTTACAAATTGATGCAGCAAAGCGATTTGGTATGTCCGCTCAAGCC GTATTAGATACGTGCCAACGCCTATATGAAACTCATCGTTTGATTACTTATCCGCGTTCTGATTGTCGCTATTTGCCCGA AGAACATTTTGCCGAACGCCATAATGTATTAAATGCAATTTCAACCCATTGTGAAGCTTATCAAGTCTTACCAAATGTTA TTTTAACTGAACAGAGAAATCGCTGTTGGAATGATAAAAAAGTAGAGGCTCACCATGCAATCATTCCTACTGCCAAAAAT CGTCCAGTAAATCTAACACAAGAAGAACGTAATATTTACAGCCTTATCGCTCGCCAATATTTAATGCAATTTTGCCCTGA CGCAGAATATCGTAAAAGTAAAATCACATTAAATATCGCTGGCGGTACTTTTATAGCTCAAGCACGAAATTTACAAACGG CTGGGTGGAAAGAATTGTTAGGCAAAGAAGACGACACAGAAAATCAAGAACCCTTATTACCAATAGTAAAGAAAGGACAA ATTTTGCATTGTGAACGCGGAGAAGTGATGAGTAAAAAAACTCAGCCACCAAAGCCCTTCACTGATGCAACCTTGCTTTC AGCAATGACGGGCATTGCGCGATTTGTGCAGGATAAAGAACTCAAAAAAATTCTGCGAGAAACCGATGGATTGGGTACAG AGGCTACTCGCGCTGGCATCATTGAATTACTTTTTAAACGCGGTTTTTTAACTAAAAAAGGGCGAAATATTCATAGCACA GAAACAGGAAGAATTTTAATTCAGGCATTACCAAATATTGCCACCCAACCAGATATGACGGCTCATTGGGAATCGCAACT CACAGACATTAGTCAAAAACAAGCAACCTATCAACAATTTATGCATAACTTGAATCAAATATTGCCTGATTTAGTCCGTT TTGTAGATCTTAATGCATTAAGACAATTAAGCCGCATTAAAATGATTAAATCCGATAGAGCGAAACCTAAAAGTGCGGTA AAAAAATCGAGTAAATCAAACGGTGAGACTGATTAA Protein sequence : MRLFIAEKPSLARAIADVLPKPHQRGDGFIKCGDNDVVTWCVGHLLEQAEPDAYDPKFKQWRLEHLPIIPEKWQLLPRKE VKKQLSVVEKLIHQADTLVNAGDPDREGQLLVDEVFSYANLSAEKRDKILRCLISDLNPSAVEKAVKKLQPNRNFIPLAT SALARARADWLYGINMTRAYTIRGRQTGYDGVLSVGRVQTPVLGLIVRRDLEIEHFQPKDFFEVQAWVNPESKEEKTPEK STALFSALWQPSKACEDYQDDDGRVLSKGLAEKVVKRITNQPAEVTEYKDVREKETAPLPYSLSALQIDAAKRFGMSAQA VLDTCQRLYETHRLITYPRSDCRYLPEEHFAERHNVLNAISTHCEAYQVLPNVILTEQRNRCWNDKKVEAHHAIIPTAKN RPVNLTQEERNIYSLIARQYLMQFCPDAEYRKSKITLNIAGGTFIAQARNLQTAGWKELLGKEDDTENQEPLLPIVKKGQ ILHCERGEVMSKKTQPPKPFTDATLLSAMTGIARFVQDKELKKILRETDGLGTEATRAGIIELLFKRGFLTKKGRNIHST ETGRILIQALPNIATQPDMTAHWESQLTDISQKQATYQQFMHNLNQILPDLVRFVDLNALRQLSRIKMIKSDRAKPKSAV KKSSKSNGETD |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| topB | NP_458624.1 | topoisomerase B | Not tested | SPI-7 | Protein | 2e-110 | 41 |
| topB | NP_807836.1 | DNA topoisomerase III | Not tested | SPI-7 | Protein | 2e-110 | 41 |
| topB | AAF14809.1 | topoisomerase B | Not tested | SPI-7 | Protein | 1e-110 | 41 |
| pph56 | CAI36097.1 | Topoisomerase IA | Not tested | PPHGI-1 | Protein | 8e-101 | 41 |
