Gene Information

Name : HI0286 (HI0286)
Accession : NP_438453.1
Strain : Haemophilus influenzae Rd KW20
Genome accession: NC_000907
Putative virulence/resistance : Unknown
Product : aminotransferase AlaT
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0436
EC number : 2.6.1.2
Position : 319804 - 321018 bp
Length : 1215 bp
Strand : +
Note : broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor

DNA sequence :
ATGCGATTATTCCCAAAATCCGACAAATTAGAACACGTATGTTATGACATTCGCGGACCTGTGCATAAAGAAGCACTACG
CTTAGAAGAAGAAGGCAATAAAATTTTAAAACTTAATATCGGCAATCCCGCACCTTTCGGCTTTGAAGCACCAGATGAAA
TTTTGGTGGACGTATTGCGTAATTTGCCGTCAGCTCAAGGCTACTGCGATTCAAAAGGATTATATTCTGCTCGTAAAGCC
ATTGTTCAATATTACCAATCAAAAGGGATTCTCGGCGCGACCGTCAATGATGTGTATATTGGTAACGGCGTATCTGAGCT
TATCACAATGGCAATGCAAGCATTGCTCAATGATGGCGATGAAGTGCTTGTGCCGATGCCTGATTATCCGCTTTGGACTG
CTGCGGTAACCCTTTCTGGCGGTAAAGCAGTGCATTATCTCTGTGATGAAGACGCAAATTGGTTTCCCACTATTGATGAT
ATTAAAGCAAAGGTGAATGCGAAAACTAAAGCGATTGTCATCATCAACCCGAACAACCCAACGGGTGCTGTGTATAGCAA
AGAATTATTACAAGAAATTGTGGAAATCGCGCGTCAAAATAATTTAATTATCTTCGCTGACGAAATCTACGACAAAATTT
TATATGATGGCGCGGTGCATCATCACATTGCCGCACTTGCTCCTGATTTATTAACCGTTACATTGAATGGGTTATCAAAA
GCTTATCGAGTTGCAGGCTTCCGCCAAGGCTGGATGATTTTGAACGGCCCAAAACATAATGCGAAAGGTTATATTGAAGG
CTTGGATATGCTGGCATCAATGCGTTTATGTGCCAACGTACCAATGCAACATGCAATTCAAACCGCACTTGGTGGCTATC
AAAGTATTAATGAATTTATTTTACCAGGCGGTCGATTACTTGAGCAACGAAACAAAGCCTATGATCTCATCACTCAAATT
CCAGGCATTACTTGCGTGAAACCAATGGGGGCGATGTATATGTTCCCGAAAATTGATGTGAAAAAATTCAATATTCACAG
TGATGAAAAAATGGTGCTGGATTTACTCCGCCAAGAAAAAGTACTACTTGTGCACGGTAAAGGATTTAATTGGCATTCAC
CAGATCACTTCCGTATTGTTACTCTTCCTTATGTGAATCAGCTTGAAGAAGCCATTACAAAATTAGCAAGATTTTTGTCG
GATTACCGTCAATAA

Protein sequence :
MRLFPKSDKLEHVCYDIRGPVHKEALRLEEEGNKILKLNIGNPAPFGFEAPDEILVDVLRNLPSAQGYCDSKGLYSARKA
IVQYYQSKGILGATVNDVYIGNGVSELITMAMQALLNDGDEVLVPMPDYPLWTAAVTLSGGKAVHYLCDEDANWFPTIDD
IKAKVNAKTKAIVIINPNNPTGAVYSKELLQEIVEIARQNNLIIFADEIYDKILYDGAVHHHIAALAPDLLTVTLNGLSK
AYRVAGFRQGWMILNGPKHNAKGYIEGLDMLASMRLCANVPMQHAIQTALGGYQSINEFILPGGRLLEQRNKAYDLITQI
PGITCVKPMGAMYMFPKIDVKKFNIHSDEKMVLDLLRQEKVLLVHGKGFNWHSPDHFRIVTLPYVNQLEEAITKLARFLS
DYRQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aspC YP_005684271.1 Aminotransferase AlaT Not tested PiCp 7 Protein 5e-130 64
aspC YP_003784329.1 aspartate aminotransferase Not tested PiCp 7 Protein 5e-130 64
aspC YP_005686363.1 Aminotransferase AlaT Not tested PiCp 7 Protein 5e-130 64
aspC YP_005682179.1 Aminotransferase AlaT Not tested PiCp 7 Protein 5e-130 64