Gene Information

Name : pepA (HI1705)
Accession : NP_439847.1
Strain : Haemophilus influenzae Rd KW20
Genome accession: NC_000907
Putative virulence/resistance : Unknown
Product : leucyl aminopeptidase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0260
EC number : 3.4.11.1
Position : 1776575 - 1778050 bp
Length : 1476 bp
Strand : +
Note : catalyzes the removal of N-terminal amino acids preferably leucine from various peptides

DNA sequence :
ATGAAATATCAAGCAAAAAATACCGCACTTTCTCAAGCCACTGATTGCATTGTTTTAGGCGTCTATGAAAATAATAAATT
TTCAAAAAGTTTTAATGAAATCGATCAATTAACCCAAGGTTATTTAAACGATTTAGTCAAATCAGGTGAGCTCACTGGCA
AATTAGCCCAAACCGTTTTACTTCGTGATCTTCAAGGTTTATCTGCTAAACGCCTATTAATCGTTGGCTGTGGCAAAAAA
GGAGAACTCACAGAGCGTCAATATAAACAAATCATCCAAGCTGTATTAAAGACACTAAAAGAAACCAACACGCGTGAAGT
CATTTCTTATTTAACTGAAATTGAATTAAAAGATCGCGATCTTTATTGGAATATCCGCTTTGCCATTGAAACGATTGAAC
ACACCAATTATCAATTTGATCATTTCAAATCTCAAAAAGCAGAAACCTCTGTTTTAGAATCTTTCATCTTCAATACGGAT
TGTGCTCAAGCACAACAAGCTATTTCTCACGCCAATGCCATTAGCTCAGGCATAAAAGCAGCACGCGACATCGCAAATAT
GCCACCAAATATTTGTAATCCAGCTTATCTTGCTGAGCAAGCAAAAAATTTAGCAGAAAATTCTACCGCACTTTCATTGA
AAGTTGTGGATGAAGAAGAAATGGCAAAACTTGGAATGAACGCTTATCTTGCCGTCTCAAAAGGCTCTGAAAACCGTGCT
TATATGTCTGTTTTAACATTCAATAATGCGCCAGATAAAAACGCCAAACCCATTGTACTTGTAGGCAAGGGATTAACCTT
TGATGCAGGCGGTATTTCACTTAAACCCGCCGCAGATATGGATGAAATGAAATATGATATGTGCGGTGCAGCCTCTGTCT
TCGGCACAATGAAAACCATTGCACAGTTGAACTTGCCATTAAACGTTATTGGTGTTTTAGCAGGTTGTGAAAATCTGCCA
GATGGCAATGCTTATCGCCCAGGCGATATTCTTACCACTATGAATGGTTTAACCGTAGAAGTTCTTAATACTGATGCAGA
AGGTCGATTAGTGCTTTGTGATACCCTTACTTATGTTGAGCGTTTTGAACCTGAGCTTGTTATTGATGTTGCAACCTTGA
CTGGTGCTTGTGTGGTTGCACTAGGGCAACACAATAGCGGCTTAGTTTCTACAGATAACAATCTTGCCAATGCACTACTC
CAAGCCGCAACAGAAACCACTGACAAAGCGTGGCGTTTACCATTAAGCGAAGAATATCAAGAGCAACTTAAATCGCCTTT
CGCCGACCTTGCCAACATTGGTGGTCGCTGGGGGGGCGCAATTACAGCGGGTGCATTTTTGTCTAATTTCACGAAAAAAT
ATCGCTGGGCACATTTAGACATCGCTGGTACAGCTTGGTTACAAGGTGCAAATAAAGGTGCAACAGGTCGCCCTGTTTCG
CTATTAACCCAATTTTTGATTAATCAGGTTAAATAA

Protein sequence :
MKYQAKNTALSQATDCIVLGVYENNKFSKSFNEIDQLTQGYLNDLVKSGELTGKLAQTVLLRDLQGLSAKRLLIVGCGKK
GELTERQYKQIIQAVLKTLKETNTREVISYLTEIELKDRDLYWNIRFAIETIEHTNYQFDHFKSQKAETSVLESFIFNTD
CAQAQQAISHANAISSGIKAARDIANMPPNICNPAYLAEQAKNLAENSTALSLKVVDEEEMAKLGMNAYLAVSKGSENRA
YMSVLTFNNAPDKNAKPIVLVGKGLTFDAGGISLKPAADMDEMKYDMCGAASVFGTMKTIAQLNLPLNVIGVLAGCENLP
DGNAYRPGDILTTMNGLTVEVLNTDAEGRLVLCDTLTYVERFEPELVIDVATLTGACVVALGQHNSGLVSTDNNLANALL
QAATETTDKAWRLPLSEEYQEQLKSPFADLANIGGRWGGAITAGAFLSNFTKKYRWAHLDIAGTAWLQGANKGATGRPVS
LLTQFLINQVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00295 YP_008207760.1 Leucyl aminopeptidase Not tested AbaR25 Protein 1e-90 49
BJAB0868_00299 YP_008211625.1 Leucyl aminopeptidase Not tested AbaR26 Protein 1e-90 49