Gene Information

Name : HI0145 (HI0145)
Accession : NP_438314.1
Strain : Haemophilus influenzae Rd KW20
Genome accession: NC_000907
Putative virulence/resistance : Virulence
Product : N-acetylmannosamine-6-phosphate 2-epimerase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG3010
EC number : 5.1.3.9
Position : 160522 - 161208 bp
Length : 687 bp
Strand : -
Note : Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate

DNA sequence : 
ATGTCTAAATTATCTTATCAAGAAGTGCTTTCTCAAATTCAATATGGTCTTATTTCTTCTTGCCAACCTGTCGATGATGG
CCCAATGGATAAACCTGAAATCGTTTCTGCTATGGCTCAGGCTTCAGTTATGGGCGGACGTTCTGGCTTACGTATTGAGG
GTGTTGATAACCTTAAAGCAACCCGTCCTTTTGTGAATGTCCCGATTATCGGAATTGTAAAACGTGATTTGCCTGATAGT
CCCGTGCGTATTACGCCGTTTTTACAAGATATTGAAGATCTAGCCAATGCTGGCGCGGATATTATTGCAGTAGATGGCAC
GAGCCGTCCACGTCCTGTGGATATTGAAAGTGCGGTGAAAAAAATCCACGAAATGGGCTGTTTGGCAATGGCAGATTGTT
CTAATTTAGAAGAAGGCTTGTATTGTAAAGCGCTTGGTTTTGATATTGTCGGCAGTACGATGTCAGGTTATACAGGTGGC
GCAGTGCCAGAAGAACCAGATTATCAATTAGTGAAAGATTTAAAATCAGCGGGTTGTTTTGTGATGGCTGAGGGGCGTTA
TAACACACCAGAATTGGCAAAAGTGGCAATTGAAATTGGTGCAGATTGCGTGACTGTAGGTTCAGCCTTAACTCGTCTTG
AACATATTGTGAGTTGGTTTGCTAATTCAGTGAAATCTGCAAGATAG

Protein sequence : 
MSKLSYQEVLSQIQYGLISSCQPVDDGPMDKPEIVSAMAQASVMGGRSGLRIEGVDNLKATRPFVNVPIIGIVKRDLPDS
PVRITPFLQDIEDLANAGADIIAVDGTSRPRPVDIESAVKKIHEMGCLAMADCSNLEEGLYCKALGFDIVGSTMSGYTGG
AVPEEPDYQLVKDLKSAGCFVMAEGRYNTPELAKVAIEIGADCVTVGSALTRLEHIVSWFANSVKSAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC1781 NP_231416.1 N-acetylmannosamine-6-phosphate 2-epimerase Not tested VPI-2 Protein 2e-52 57
nanE ACA01846.1 N-acetylmannosamine-6-phosphate epimerase Not tested VPI-2 Protein 3e-52 57
VC0395_A1378 YP_001217321.1 N-acetylmannosamine-6-phosphate 2-epimerase Not tested VPI-2 Protein 3e-52 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HI0145 NP_438314.1 N-acetylmannosamine-6-phosphate 2-epimerase VFG1114 Protein 6e-53 57