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Name : lysS (HI1211) Accession : NP_439367.1 Strain : Haemophilus influenzae Rd KW20 Genome accession: NC_000907 Putative virulence/resistance : Virulence Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 1277530 - 1279038 bp Length : 1509 bp Strand : - Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA DNA sequence : ATGTCAGAACAAGAAGTTAAAGAATTAGATCTCAATGGCGAAATGCTCGTCCGTCGTGAAAAATTAGCCGCATTACGTGC AAAAGGTAATGCCTTTCCAAATAAGTTTCGTCGTGATGCTCTCGCACAAGATTTGCACAATCAATATGATGCAGAAGACG GGGAAATCTTAAAAGAAAAAGGCATTGAAGTACAAGTTGCTGGTCGTATTATGACTCGCCGTGCAATGGGTAAAGCAACT TTTATCACTATTCAAGATATGAGCGGTAAAATCCAACTTTATGTTGCACGCGATAATTTGCCTGAAGGTGTTTATAAAGA TGACGTTGGTACTTGGGATTTAGGTGATATCGTTGGCATTAAAGGCACTTTATTTAAAACAAAAACTGATGAACTCACCG TTAAAACTACGGAAGTTCAACTTTTAACCAAAGCACTTCGCCCATTACCAGACAAATTCCATGGTTTAACCGACCAAGAA GTTCGTTATCGCCAACGTTATTTAGATTTAATTTCTAACGAAGAATCTCGCCGCACTTTTATTATTCGTTCTAAAGTTGT CGCGGGTATTCGTGAATATTTCATTTCTAAAGGCTTTATGGAAGTGGAAACGCCAATGTTACAAGTGATTCCAGGCGGTG CATCTGCGCGTCCTTTCGTGACTCATCACAATGCATTAGATGTGGATATGTATTTACGTATCGCACCTGAACTTTATTTA AAACGCTTAGTCGTTGGTGGGTTTGAACGAGTATTTGAATTAAACCGTAACTTCCGTAATGAAGGGGTTTCTGTTCGTCA TAATCCAGAATTTACTATGCTTGAATACTATCAAGCATATGCGGACTACCATGATTTAATGGATAACACCGAAGAACTTC TTCGTAAATTAGCGATTGATATTCTTGGTACAACCATTGTGAAATACGGTGATTTAGAATTTGACTTCGGCAAACCATTT GAGCGTATTACATTACATGATGCAACCATTAAATATGGTGCAGATAAAGGTATCGTAAAAGAAGATCTTTATGACTTCGA TCGTGCAAAAGCAACTGCTGAACGCTTAGGTATTGAAGTACAAAAATCTTGGGGTTTAGGCAGCATTGTCAATGCAATCT TTGAAGAAGTGGCTGAACATCACTTAATTCAACCAACCTTTCTTAATGGCTCACCTGCGGAAATTTCGCCACTTGCACGT CGTAATGATGAAAACCCTGAAGTGACTGACCGTTTTGAATTATTCATCGGCGGACGTGAAATTGGTAACGGTTTCTCAGA ATTAAATGACGCGGAAGATCAAAATGAACGCTTTGATGCACAAGTGGCTGCGAAAGAAGCGGGCGATGATGAAGCGATGT TTAAAGATGAAGACTTTGTTGTTGCACTAGAACACGGCTTACCACCAACAGCTGGGGAAGGTTTAGGTATCGACCGTCTA GCGATGCTTTATGCAAATGCACCGTCAATTCGTGATGTTATCTTATTCCCTGCAATGCGTCAGAAATAA Protein sequence : MSEQEVKELDLNGEMLVRREKLAALRAKGNAFPNKFRRDALAQDLHNQYDAEDGEILKEKGIEVQVAGRIMTRRAMGKAT FITIQDMSGKIQLYVARDNLPEGVYKDDVGTWDLGDIVGIKGTLFKTKTDELTVKTTEVQLLTKALRPLPDKFHGLTDQE VRYRQRYLDLISNEESRRTFIIRSKVVAGIREYFISKGFMEVETPMLQVIPGGASARPFVTHHNALDVDMYLRIAPELYL KRLVVGGFERVFELNRNFRNEGVSVRHNPEFTMLEYYQAYADYHDLMDNTEELLRKLAIDILGTTIVKYGDLEFDFGKPF ERITLHDATIKYGADKGIVKEDLYDFDRAKATAERLGIEVQKSWGLGSIVNAIFEEVAEHHLIQPTFLNGSPAEISPLAR RNDENPEVTDRFELFIGGREIGNGFSELNDAEDQNERFDAQVAAKEAGDDEAMFKDEDFVVALEHGLPPTAGEGLGIDRL AMLYANAPSIRDVILFPAMRQK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD66193.1 | putative lysil-tRNA synthetase LysU | Not tested | PAI III 536 | Protein | 2e-152 | 64 |
| lysS | YP_005163386.1 | lysyl-tRNA synthetase | Not tested | Not named | Protein | 4e-89 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| lysS | NP_439367.1 | lysyl-tRNA synthetase | VFG1668 | Protein | 1e-152 | 64 |
