Gene Information

Name : serS (HI0110)
Accession : NP_438284.1
Strain : Haemophilus influenzae Rd KW20
Genome accession: NC_000907
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 117827 - 119116 bp
Length : 1290 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATCGATCCAAATTTACTCCGTAATAATTTAGCAGAAGTCGCAGAAAAATTAAAAGTAAAACGCAACTTTATGCTTGA
TACGGAAAAACTCACCGCGTTAGAAGATCAGCGCAAAAACTTACAAGTCACTACCGAAAACTTACAAGCGGAACGTAATG
CTCGTTCCAAAGCCATTGGTGCTGCTAAAGCGCGTGGTGAAGATATCGCACCATTATTGGCAGAAATGGATGATATGGGC
AATCAATTGACTGAAGCAAAAGCACAATTAGATGCGGTACTTGCAGAAATCAATCAAATTGCATTAAGTATTCCAAATCT
ACCCGCAGACGAAGTGCCATTAGGCAAAGATGACACAGAAAATAAAGAAATCTTACGTTGGGGTACACCGCGTACATTTG
ATTTTGAAGTGAAAGATCATATCACTTTGGGTGAAGAAGCAAATGGCTTAGATTTTGCTGCTGGGGCTAAATTAGCTGGT
GCACGTTTTGCCGTAATGAAAGGTCAAATCGCTAAAATGCACCGTGCATTGGCACAATTCATGTTAGATCTTCATACGGA
ACAACACGGCTATTTAGAAACCTATGTGCCTTATTTAGTAAATCACGCCACACTTTATGGAACAGGGCAATTACCAAAAT
TCGGGGAAGATTTATTCCATACTTTAGCCTTAGAAGGCGAACAACCTTACGCATTAATTCCAACTGCAGAAGTGCCCGTC
ACTAATTTAGTGCGTGACGTGATTATTGATGAAGCAGAATTACCAATAAAAATGACCGCACATACGCCATGTTTCCGTTC
TGAAGCAGGTTCTTACGGTCGTGATACTCGTGGTTTAATTCGTATGCACCAATTTGATAAAGTAGAAATGGTACAAATCG
TTGATCCAGATAAATCAATGGAAGCACTTGAAGAATTAACAGGTCATGCGGAAAAAGTATTGCAATTATTAAATTTACCA
TACCGTAAAGTTTTACTTTGCACAGGCGATATGGGCTTTGGTTCTTGCAAAACTTACGATTTAGAAGTTTGGGTGCCTGC
ACAAAATACTTATCGAGAAATTTCTTCTTGCTCAAATATGTGGGATTTCCAAGCTCGCCGTATGCAAGCACGTTGTAAAG
CAAAAGGCGATAAGAAAACTCGCTTAGTGCACACATTAAATGGTTCAGGCTTAGCGGTTGGTCGTACTTTAGTGGCTGTA
CTTGAAAACTATCAAAATGCCGATGGTTCAATTACCGTGCCAGAAGAGCTACGTCCATATATGGGCGGATTAGACGTTAT
CGGAAAATAA

Protein sequence :
MIDPNLLRNNLAEVAEKLKVKRNFMLDTEKLTALEDQRKNLQVTTENLQAERNARSKAIGAAKARGEDIAPLLAEMDDMG
NQLTEAKAQLDAVLAEINQIALSIPNLPADEVPLGKDDTENKEILRWGTPRTFDFEVKDHITLGEEANGLDFAAGAKLAG
ARFAVMKGQIAKMHRALAQFMLDLHTEQHGYLETYVPYLVNHATLYGTGQLPKFGEDLFHTLALEGEQPYALIPTAEVPV
TNLVRDVIIDEAELPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVDPDKSMEALEELTGHAEKVLQLLNLP
YRKVLLCTGDMGFGSCKTYDLEVWVPAQNTYREISSCSNMWDFQARRMQARCKAKGDKKTRLVHTLNGSGLAVGRTLVAV
LENYQNADGSITVPEELRPYMGGLDVIGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 7e-98 53