Gene Information

Name : tktA (HI1023)
Accession : NP_439183.1
Strain : Haemophilus influenzae Rd KW20
Genome accession: NC_000907
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1087262 - 1089259 bp
Length : 1998 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGGCAACTCGTAGACAATTAGCCAATGCAATTCGTGTCTTAGCAATGGATTCTGTACAAAAAGCGAAATCTGGTCACCC
TGGTGCACCAATGGGGATGGCGGATATTGCTGAAGTATTATGGCGCGACTTTTTAAAACACAATCCAACCAATCCTAAAT
GGGCTGATCGAGATCGTTTTGTACTTTCTAACGGCCATGGTTCTATGTTGATTTATAGTCTTTTACATTTAACTGGCTAT
GATCTTTCTATCGAAGATTTAAAACAATTCCGTCAATTACATTCTAAAACCCCAGGTCACCCAGAATATGGTTATGCCCC
TGGTGTTGAAACCACGACTGGCCCGTTAGGTCAAGGTATCACTAATGCGGTGGGTATGGCAATTGCTGAGAAAACCTTAG
CTGGACAATTTAACCGTGAAGGCCATGAAATTGTCGATCACCACACTTATGTGTTCTTAGGCGATGGTTGTTTAATGGAA
GGGATTTCTCACGAGGCTTGCTCTTTAGCAGGAACCTTAGGTCTGGGTAAATTAATCGCATTCTACGATGACAACAATAT
TTCCATTGATGGTCATGTTGATGGCTGGTTCAGTGATGACACTGCCGAGCGTTTTGAAGCTTATGGCTGGCAAGTAATCC
GTAATGTAGATGGTCACGATGCAGAGCAAATTCGTGCTGCTACCATTCTTGCTCAAGCAGAAAAAGGAAAACCAACGTTA
ATTATTTGTAAAACCATCATCGGCTTTGGTTCACCAAATAAATCAGGTTCTCATGATTCCCATGGCGCACCATTAGGCGA
TGAAGAAATCGATTTAACCCGTAAAGCACTTGGTTGGGAATATGCGCCATTTGAAATTCCAGCTGAATACTATGCTGAAT
GGTCGGCAAAAGAGAAAGGTGCTGCAGCAGAAAAATCTTGGGAAGAAAAATTTGCCGCTTATGCAAAAGCCTATCCTGAA
TTAGCAGCAGAATTTAAACGTCGTGTTTCTGGCGAATTACCAACAAACTGGGCGGCAGAATCTAAAGCGTTCATCGAAAA
ATTACAAGCAAATCCAGCGAGTATTGCAAGCCGTAAAGCATCACAAAATGCTATCGAAGCTTATGCGCACGTATTACCTG
AATTCTTAGGTGGCTCTGCAGACTTAGCAAGCTCTAACTTAACGTTATGGAGTGGTTCTAAACCAATTCGTGCCCACGAA
AACGTAGGTGGTAACTACATTAACTACGGCGTTCGTGAATTTGGTATGTCTGCCATTATGAACGGTATTGCTTTACACGG
CGGTTTCATTCCTTACGGCGCAACCTTCTTAATGTTCTACGAATATGCTCACAATGCGGTGCGTATGGCAGCATTAATGA
AACAACGCACATTATTCGTTTATACCCACGATTCCATTGGTTTAGGCGAAGATGGGCCTACACACCAACCAGTAGAACAA
ACGGCTTCACTACGCTTAATTCCAAACCTTGAAACATGGCGTCCATGTGACCAAGTTGAATCAGCCATCGCATGGCAACA
AGCGGTTGAACGTCAAGATGGCCCAAGTGCGTTGATCTTTACCCGTCAAAACTTAGCCCAAATGGACCGCACTTCTGCAC
AATTAGATGCGGTTAAACGTGGTGCTTATGTGTTAAAAGACTGTGATGGCACACCTGAGTTAATCTTCATTGCGACAGGT
TCTGAAGTGGAATTAGCAGTGCAAGCAGCCGAAGCATTAAGTGCTGAAGGTAAAAAAGTACGCGTTGTTTCTATGCCAAG
TACTAACCGTTTCGATAAACAAGATGCAGCGTACCGTGAAAGTGTATTACCTGCAGCGGTAACCAAACGTGTTGCGATTG
AAGCGGGTATTGCTGACTTCTGGTATAAATACGTTGGATTCAATGGTCGTGTTATCGGTATGAATAGCTTTGGCGAATCC
GCACCAGCAGATCAATTATTCAAACTCTTTGGTTTCACTGTTGAAAACGTGGTAGCAAAAGCGAAAGAAATTCTTTAA

Protein sequence :
MATRRQLANAIRVLAMDSVQKAKSGHPGAPMGMADIAEVLWRDFLKHNPTNPKWADRDRFVLSNGHGSMLIYSLLHLTGY
DLSIEDLKQFRQLHSKTPGHPEYGYAPGVETTTGPLGQGITNAVGMAIAEKTLAGQFNREGHEIVDHHTYVFLGDGCLME
GISHEACSLAGTLGLGKLIAFYDDNNISIDGHVDGWFSDDTAERFEAYGWQVIRNVDGHDAEQIRAATILAQAEKGKPTL
IICKTIIGFGSPNKSGSHDSHGAPLGDEEIDLTRKALGWEYAPFEIPAEYYAEWSAKEKGAAAEKSWEEKFAAYAKAYPE
LAAEFKRRVSGELPTNWAAESKAFIEKLQANPASIASRKASQNAIEAYAHVLPEFLGGSADLASSNLTLWSGSKPIRAHE
NVGGNYINYGVREFGMSAIMNGIALHGGFIPYGATFLMFYEYAHNAVRMAALMKQRTLFVYTHDSIGLGEDGPTHQPVEQ
TASLRLIPNLETWRPCDQVESAIAWQQAVERQDGPSALIFTRQNLAQMDRTSAQLDAVKRGAYVLKDCDGTPELIFIATG
SEVELAVQAAEALSAEGKKVRVVSMPSTNRFDKQDAAYRESVLPAAVTKRVAIEAGIADFWYKYVGFNGRVIGMNSFGES
APADQLFKLFGFTVENVVAKAKEIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 77
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 69