Gene Information

Name : metC (APE_1226)
Accession : NP_147803.1
Strain : Aeropyrum pernix K1
Genome accession: NC_000854
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 774777 - 775931 bp
Length : 1155 bp
Strand : +
Note : -

DNA sequence :
GTGAGGGGCTTCACCACCAAGGCCGTCCACGCGGGGGAGGACCCCCGGGAGACCCTCCACGGCGACGTCGTCCACCCTAT
ACACCTCTCCGTCACGTATTGGAAGAGGAGTGTGGCTGAGGCCGAGGAGGGCTACGTGTACTCGAGGACCTCCAACCCCA
CCAGGGACGCCCTTGAGAAGAAGCTGGCCGCCCTCGAGAACGCCAGGTACGCCCTGGCCTTCTCCTCCGGCCTGGCGGCC
GAGGCCACCGTCATACTCGCCCTGCTGAGGGAGGGAGACCATATAGTGGCGTTCGACGACCTCTACGGCGGCACCAAGAG
GCTCTTCCAGAGGGTGATGGCCCGGTTCGGGATTAAGGTCACCTACGTGGACGCCCGCGACCCCGGGAACATCGAGAAGG
CCCTGACACCCGCCACCAGGATGATATGGCTCGAGACCCCCACCAACCCGCTGCTGAAGCTGACCGACATCAGGGCCGCG
GCGGAGATAGCGTCCCGGGCGGGGGCTTACCTGGTGGTAGACAACACCTTCGCCACCCCATACTTCCAGAGGCCCCTGGA
GCTGGGGGCGGATATAGTGGTGCACAGCGCCACTAAATACCTCTCAGGCCACTCAGACCTCCTCGCGGGGGCCGTGATGG
TCAACAGCAGCGAGGTCTACGAGAAGCTCAAGTACCACCAGAACGCCGTCGGCGCCGTCCCACCACCCCTCGACTCCTAC
CTCCTCATGAGATCCCTCAAAACCCTAGCCCTCAGGATGGAGTGGCACCAGCACAACGCCATGAAGATAGCCGAACACCT
AGAGAGCCACCCGAAGGTGGACCGGGTAATCTACCCCGGCCTCTCAACACACCCCCAGCACAGCCTGGCGAAGAGGCAGA
TGACAGGCTACAGCGGCATGCTCTCCTTCGAGCTCAAGGGGGGCGCCGGGGCGGCGGTCAGGTTCGTAGAGAGCCTCAGG
ATCATAGCCCTCGCCGAGAGCCTAGGAGGGGTAGAATCCCTAGTGGAGATACCCTCGCTCATGACACACGCCTCAATACC
TAGGGAGGAGAGGCTCAAGAAAGGGATAACAGACGGCCTAGTAAGACTCTCAGTAGGCATAGAGGACCTCGAAGACCTCA
TAGAAGACATAGAACAAGCCCTCAAGAAAACATAG

Protein sequence :
MRGFTTKAVHAGEDPRETLHGDVVHPIHLSVTYWKRSVAEAEEGYVYSRTSNPTRDALEKKLAALENARYALAFSSGLAA
EATVILALLREGDHIVAFDDLYGGTKRLFQRVMARFGIKVTYVDARDPGNIEKALTPATRMIWLETPTNPLLKLTDIRAA
AEIASRAGAYLVVDNTFATPYFQRPLELGADIVVHSATKYLSGHSDLLAGAVMVNSSEVYEKLKYHQNAVGAVPPPLDSY
LLMRSLKTLALRMEWHQHNAMKIAEHLESHPKVDRVIYPGLSTHPQHSLAKRQMTGYSGMLSFELKGGAGAAVRFVESLR
IIALAESLGGVESLVEIPSLMTHASIPREERLKKGITDGLVRLSVGIEDLEDLIEDIEQALKKT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-72 48
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-70 47
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 7e-54 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metC NP_147803.1 cystathionine gamma-synthase BAC0207 Protein 1e-62 46