Gene Information

Name : TM0208 (TM0208)
Accession : NP_228023.1
Strain : Thermotoga maritima MSB8
Genome accession: NC_000853
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 223226 - 224626 bp
Length : 1401 bp
Strand : -
Note : similar to GB:AL009126 percent identity: 64.53; identified by sequence similarity

DNA sequence :
GTGCGAAGTACAAAGATCGTATGTACGGTCGGACCAAGAACAGACAGCTATGAAATGATAGAAAAGATGATAGACCTTGG
AGTGAACGTCTTCAGAATAAACACCTCACATGGTGACTGGAACGAGCAGGAACAGAAAATACTCAAAATAAAAGATCTGA
GAGAGAAAAAGAAAAAACCCGTAGCCATTCTGATCGATCTTGCGGGGCCGAAGATCAGAACCGGATACCTCGAAAAAGAG
TTTGTGGAATTAAAAGAAGGCCAGATCTTCACTCTCACCACAAAGGAAATACTTGGAAACGAACACATAGTCTCGGTGAA
TCTCAGCTCTCTTCCAAAGGACGTGAAGAAAGGAGACACCATTCTGCTGAGCGATGGAGAGATAGTGCTTGAGGTAATTG
AAACAACCGATACAGAAGTGAAAACAGTGGTGAAAGTCGGTGGAAAGATCACACACAGGAGAGGTGTGAACGTACCGACG
GCCGATCTTTCGGTGGAATCCATAACGGACAGAGACAGAGAATTCATAAAACTCGGAACGTTGCATGACGTTGAATTTTT
CGCTCTTTCTTTTGTGAGAAAGCCAGAGGACGTGCTCAAGGCAAAAGAAGAGATCAGAAAACACGGAAAGGAAATACCTG
TAATCTCCAAAATAGAAACGAAAAAGGCTCTGGAGCGTCTCGAGGAGATAATAAAGGTGAGCGATGGAATCATGGTCGCA
CGCGGTGACCTGGGAGTGGAGATACCCATAGAAGAAGTCCCCATCGTTCAGAAAGAAATCATCAAACTCTCCAAGTACTA
CTCCAAACCAGTCATAGTCGCAACTCAGATACTCGAATCGATGATAGAAAATCCGTTCCCCACGAGGGCAGAGGTCACCG
ACATAGCCAACGCCATCTTCGATGGAGCGGACGCCCTGCTCCTCACAGCGGAAACAGCGGTTGGAAAACATCCCCTGGAA
GCCATAAAGGTGCTGAGTAAAGTAGCAAAAGAAGCCGAAAAAAAACTGGAATTTTTCAGAACGATAGAATACGATACCAG
CGACATATCTGAGGCTATATCACACGCCTGCTGGCAGCTCTCTGAATCTCTGAACGCGAAGCTGATCATCACACCTACCA
TATCCGGGAGTACCGCTGTTCGTGTTTCAAAGTACAACGTTTCTCAACCCATTGTGGCCCTGACACCAGAAGAGAAAACC
TACTACAGACTTTCTCTCGTGAGGAAGGTGATACCCGTTCTCGCTGAAAAATGTTCCCAGGAATTAGAGTTTATCGAAAA
AGGGCTGAAGAAAGTAGAAGAAATGGGTTTGGCAGAAAAAGGGGATCTGGTGGTTCTCACTTCCGGCGTTCCAGGAAAGG
TGGGAACGACAAACACCATAAGGGTGTTGAAGGTGGATTGA

Protein sequence :
MRSTKIVCTVGPRTDSYEMIEKMIDLGVNVFRINTSHGDWNEQEQKILKIKDLREKKKKPVAILIDLAGPKIRTGYLEKE
FVELKEGQIFTLTTKEILGNEHIVSVNLSSLPKDVKKGDTILLSDGEIVLEVIETTDTEVKTVVKVGGKITHRRGVNVPT
ADLSVESITDRDREFIKLGTLHDVEFFALSFVRKPEDVLKAKEEIRKHGKEIPVISKIETKKALERLEEIIKVSDGIMVA
RGDLGVEIPIEEVPIVQKEIIKLSKYYSKPVIVATQILESMIENPFPTRAEVTDIANAIFDGADALLLTAETAVGKHPLE
AIKVLSKVAKEAEKKLEFFRTIEYDTSDISEAISHACWQLSESLNAKLIITPTISGSTAVRVSKYNVSQPIVALTPEEKT
YYRLSLVRKVIPVLAEKCSQELEFIEKGLKKVEEMGLAEKGDLVVLTSGVPGKVGTTNTIRVLKVD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-68 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-68 42
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-68 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-68 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TM0208 NP_228023.1 pyruvate kinase VFG0479 Protein 1e-68 42