Gene Information

Name : TM0198 (TM0198)
Accession : NP_228013.1
Strain : Thermotoga maritima MSB8
Genome accession: NC_000853
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATPase subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 210687 - 213149 bp
Length : 2463 bp
Strand : +
Note : similar to PID:1001492 percent identity: 74.36; identified by sequence similarity

DNA sequence :
ATGTTTGATAAGTTCTCGGAGAAGACAGCTCAGATATTTGTAACAGCCCAGGAGGAGGCAAAAGAACTCGGGCATTCGTA
CGTCGGAACGGAGCACCTTCTGCTTGCAATTCTAAAAGTAGATAGAAGCCCGGCCGTCGAACTCCTGGAAGAAATGGGAG
CCTCGTACTCCAAGGTGAGATCCGAGATCATCTCCATGGTTGGCATGGGGATGAGAGGCTTTGTCCCTTCTCCTCAGATG
ACTCCAAGAGCCAAAAGAGTGACTGAACTCGCATACGAAGAGGCGAAGATTCTTGGAAGTGACAAGATAAACCCGGAGCA
TCTTCTCCTTGGTATTCTGAGAGAGGGAGAAGGGATTGCAATACACATTCTGAGGAAACTCGGAGTAGATATCGCTACTC
TGAGAAGAGAGATCATAGATATCTACTCCTACTCCTCGAACAAAAATCTGGAGTATGAGGAAGAGGAGGATTACACTTAC
AGAAGCGTGAAGCAACTTGAAGGCTTCGGTGTGAATCTCACAGAACTTGCAGCTAAGAAAGAACTCGACCCAGTTATTGG
AAGAGAAGAAGAAATAGAGAGAGTGATGCAGGTCCTCGTCAGAAGGAAGAAAAACAATCCTGTTCTCATAGGAGATCCTG
GAGTTGGAAAGACAGCGATAGTCGAAGGTCTGGCTCAGAGGATAGTCGCTGGAGATGTGCCCGAGATCTTGAAAAACAAG
GTGATCTTCTCTCTTGACGTGGCAGCGCTGGTTGCGGGAACCAAATACAGAGGTGAATTCGAAAAGAGGATGAAGAAGCT
CCTTCAGATCGTGACCAAGGATAAGAACATTATCCTCTTCATAGACGAGATACACACCATAGTTGGTGCTGGATCGGCTG
AGGGAGCAATCGATGCTGCGAACATTTTGAAGCCTGCTCTCGCACGTGGAGAGATAAGCTGTATAGGTGCCACCACACCG
GACGAATACAGAAGGTACATTGAAAAGGATGCGGCTCTGGAGAGAAGGTTTCAGAAGATATATGTGAAAGAACCAACTGA
GGAAGAAACGCTCGAAATATTGAAAGGTTTGAAGAGAAAATACGAAGCGCATCATAAAGTGATTTATACCGACAAGGCTC
TGGAGGCGGCCGTTTACCTTTCCAAGAGATACATAACCGATCACTATCTACCTGACAAGGCGATCGATGTGATAGACGAG
GCAGGTGCCAGAGCGAGATTGAAGGTGTTCGTGCTTCCTCCAGAACTGAAGGATATGAAGCTAGAACTGGAAAGAATAAG
AAGCGATAAGGAGCTCGCTGTTCTGAACCAGGATTACGAAAAGGCTGCACAACTGAAAGAAGAAGAGATGGAGCTGGAGG
CGGAATACAGAAAAAGGTACGCAGAGTGGAGAAGACGCGCAGAAACAGCTGTGGTAAAGGTGGATGTAGACGACGTGGCT
GAAGTGGTGTCTTCCTGGACGGGTGTTCCTCTCAGAAAGATCGAGGAAACAGAAGTCGAAAAGCTTCTCAATCTCGAAGA
GGCTCTCCACCAGAGAATCGTTGCTCAGGACGAAGCCATAAAAGCTGTAGCCAGGGCCATAAGAAGAGCAAGAAGCGGTT
TGAAGGATCCAAGAAGGCCGATAGGTGTGTTCCTGTTCCTCGGTCCAACGGGTGTTGGAAAGACAGAGCTTGCAAAGGCG
CTCGCAGAGTACCTGTTCGGGGATGAAAGGGCCCTCATCAGGTTCGACATGAGCGAATACATGGAGAGGTTCTCCGTTTC
GAGGCTCATAGGAGCACCTCCAGGATATGTGGGTTACGAAGAGGGAGGTACTCTCACGGAAAAAGTGAGAAGAAGACCGT
TCTCGGTGATCCTGTTCGACGAAATAGAGAAAGCACATCCGGACGTGTTCAACATACTGCTCCAGATAATGGACGATGGA
AGACTCACGGATTCCCAGGGACGTGAAGTTGATTTCAGGAACACGATCATCATCATGACCAGCAACATCGGAAGCTCTTA
CATCAACAAATCCAAGAGAACTCTTGGGTTTGTGGGTGACAACAACGAAGAGAAGGAATTCGAGAAAATAAAGGATCTCG
TTCTGGAAGAGGTGAAAAGAACGTTCAGACCTGAGTTCCTGAACAGGATCGATGAAACGATCATATTCCATCCGTTGAAG
AAGGAACACATCGAACAGATCATCGACATACTCTTGAGAGACCTCAGAAAGAGACTCTCGGAGAAGAACATGAAGCTTGT
ACTGACAAAGAGTGCAAAAGAGTTCCTGGTCGAAAAAGGATTCGATCCGGTGTACGGAGCAAGACCTCTGAAGAGGGCCA
TACAAAGATACGTGGAAGATCCTCTCTCTGAGGAGATCCTGAGAGGCAAGTTCAACGAAGGAGATACGATCGTCTGTAGG
GCTCGCAAAGATGCTCTTCGATTCACCAGAAAGGGTGAAAAGAAGGAGAAGGTGGTCCAGTGA

Protein sequence :
MFDKFSEKTAQIFVTAQEEAKELGHSYVGTEHLLLAILKVDRSPAVELLEEMGASYSKVRSEIISMVGMGMRGFVPSPQM
TPRAKRVTELAYEEAKILGSDKINPEHLLLGILREGEGIAIHILRKLGVDIATLRREIIDIYSYSSNKNLEYEEEEDYTY
RSVKQLEGFGVNLTELAAKKELDPVIGREEEIERVMQVLVRRKKNNPVLIGDPGVGKTAIVEGLAQRIVAGDVPEILKNK
VIFSLDVAALVAGTKYRGEFEKRMKKLLQIVTKDKNIILFIDEIHTIVGAGSAEGAIDAANILKPALARGEISCIGATTP
DEYRRYIEKDAALERRFQKIYVKEPTEEETLEILKGLKRKYEAHHKVIYTDKALEAAVYLSKRYITDHYLPDKAIDVIDE
AGARARLKVFVLPPELKDMKLELERIRSDKELAVLNQDYEKAAQLKEEEMELEAEYRKRYAEWRRRAETAVVKVDVDDVA
EVVSSWTGVPLRKIEETEVEKLLNLEEALHQRIVAQDEAIKAVARAIRRARSGLKDPRRPIGVFLFLGPTGVGKTELAKA
LAEYLFGDERALIRFDMSEYMERFSVSRLIGAPPGYVGYEEGGTLTEKVRRRPFSVILFDEIEKAHPDVFNILLQIMDDG
RLTDSQGREVDFRNTIIIMTSNIGSSYINKSKRTLGFVGDNNEEKEFEKIKDLVLEEVKRTFRPEFLNRIDETIIFHPLK
KEHIEQIIDILLRDLRKRLSEKNMKLVLTKSAKEFLVEKGFDPVYGARPLKRAIQRYVEDPLSEEILRGKFNEGDTIVCR
ARKDALRFTRKGEKKEKVVQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TM0198 NP_228013.1 ATP-dependent Clp protease, ATPase subunit VFG0079 Protein 0.0 55
TM0198 NP_228013.1 ATP-dependent Clp protease, ATPase subunit VFG0080 Protein 5e-137 53